Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Camelia Baleanu-Gogonea"'
Publikováno v:
STAR Protocols, Vol 3, Iss 1, Pp 101201- (2022)
Summary: Despite recent advances in structural determination of individual proteins, elucidating the 3-dimensional architecture of large, multiprotein complexes remains challenging, partly because of issues related to structural integrity during puri
Externí odkaz:
https://doaj.org/article/aa2806575f90470e9df12c05fa037a16
Autor:
George D. Dalton, Seh-Hoon Oh, Linda Tang, Stephanie Zhang, Amanda L. Brown, Venkateshwari Varadharajan, Camelia Baleanu-Gogonea, Valentin Gogonea, Preeti Pathak, J. Mark Brown, Anna Mae Diehl
Publikováno v:
iScience, Vol 24, Iss 9, Pp 103089- (2021)
Summary: Cellular cholesterol is regulated by at least two transcriptional mechanisms involving sterol-regulatory-element-binding proteins (SREBPs) and liver X receptors (LXRs). Although SREBP and LXR pathways are the predominant mechanisms that sens
Externí odkaz:
https://doaj.org/article/bb55d9b8b9d44c2c84e49520c90d1dcf
Autor:
Kommireddy Vasu, Iyappan Ramachandiran, Fulvia Terenzi, Debjit Khan, Arnab China, Krishnendu Khan, Aayushi Chechi, Camelia Baleanu-Gogonea, Valentin Gogonea, Paul L. Fox
Publikováno v:
iScience, Vol 24, Iss 3, Pp 102215- (2021)
Summary: Aminoacyl-tRNA synthetases (AARS) participate in decoding the genome by catalyzing conjugation of amino acids to their cognate tRNAs. During evolution, biochemical and environmental conditions markedly influenced the sequence and structure o
Externí odkaz:
https://doaj.org/article/db856183178943ba8ce357e8fdc93e98
Autor:
Rakhee Banerjee, Rachel C. Hohe, Shijie Cao, Bryan M. Jung, Anthony J. Horak, Iyappan Ramachandiran, William J. Massey, Venkateshwari Varadharajan, Natalie I. Zajczenko, Amy C. Burrows, Sumita Dutta, Maryam Goudarzi, Kala Mahen, Abigail Carter, Robert N. Helsley, Scott M. Gordon, Richard E. Morton, Christopher Strauch, Belinda Willard, Camelia Baleanu Gogonea, Valentin Gogonea, Matteo Pedrelli, Paolo Parini, J. Mark Brown
Publikováno v:
Frontiers in Physiology, Vol 15 (2024)
Introduction:The Aster-C protein (encoded by the Gramd1c gene) is an endoplasmic reticulum (ER) resident protein that has been reported to transport cholesterol from the plasma membrane to the ER. Although there is a clear role for the closely-relate
Externí odkaz:
https://doaj.org/article/a67ae9a7639840f1997cab8381632bbb
Publikováno v:
Nucleic Acids Research
In mammalian cells, eight cytoplasmic aminoacyl-tRNA synthetases (AARS), and three non-synthetase proteins, reside in a large multi-tRNA synthetase complex (MSC). AARSs have critical roles in interpretation of the genetic code during protein synthesi
Autor:
Lei Cai, Stanley L. Hazen, Ibrahim Choucair, Ryan E. Temel, Naseer Sangwan, Jennifer A. Buffa, Amanda L. Brown, Robert N. Helsley, Camelia Baleanu Gogonea, J. Mark Brown, Jose C. Garcia-Garcia, Ina Nemet, Zeneng Wang, Preeti Pathak, Valentin Gogonea
Publikováno v:
Am J Physiol Heart Circ Physiol
The gut microbe-derived metabolite trimethylamine-N-oxide (TMAO) has recently been linked to cardiovascular disease (CVD) pathogenesis, prompting the development of therapeutic strategies to reduce TMAO. Previous work has shown that experimental alte
Autor:
Krishnendu Khan, Briana Long, Camelia Baleanu-Gogonea, Valentin Gogonea, Gauravi M. Deshpande, Kommireddy Vasu, Paul L. Fox
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 119(7)
Significance Multiprotein complexes in mammalian cells are thought to form by interactions between domains of mature, fully folded proteins. However, in some cases interprotein interaction is obstructed by “buried” or inaccessible binding domains
Autor:
Valentin Gogonea, George D. Dalton, Amanda L. Brown, Anna Mae Diehl, Seh-Hoon Oh, Stephanie Zhang, Preeti Pathak, Camelia Baleanu-Gogonea, Linda Tang, Venkateshwari Varadharajan, J. Mark Brown
Publikováno v:
iScience, Vol 24, Iss 9, Pp 103089-(2021)
Summary: Cellular cholesterol is regulated by at least two transcriptional mechanisms involving sterol-regulatory-element-binding proteins (SREBPs) and liver X receptors (LXRs). Although SREBP and LXR pathways are the predominant mechanisms that sens
Autor:
Iyappan Ramachandiran, Krishnendu Khan, Fulvia Terenzi, Camelia Baleanu-Gogonea, Arnab China, Aayushi Chechi, Kommireddy Vasu, Paul L. Fox, Valentin Gogonea, Debjit Khan
Publikováno v:
iScience, Vol 24, Iss 3, Pp 102215-(2021)
iScience
iScience
Summary Aminoacyl-tRNA synthetases (AARS) participate in decoding the genome by catalyzing conjugation of amino acids to their cognate tRNAs. During evolution, biochemical and environmental conditions markedly influenced the sequence and structure of
Autor:
Paul L. Fox, Stanley L. Hazen, Camelia Baleanu-Gogonea, Jennifer A. Buffa, Joseph A. DiDonato, Ying Huang, Anthony J. DiDonato, Zhiping Wu, Valentin Gogonea, Matthew A. Wagner, Leah B. Hazen, Xiaodong Gu, John S. Parks, Ryan A. Mehl
Publikováno v:
The Journal of biological chemistry. 291(12)
The interaction of lecithin-cholesterol acyltransferase (LCAT) with apolipoprotein A-I (apoA-I) plays a critical role in high-density lipoprotein (HDL) maturation. We previously identified a highly solvent-exposed apoA-I loop domain (Leu(159)-Leu(170