Stable in vivo expression of glucose-6-phosphate dehydrogenase (G6PD) and rescue of G6PD deficiency in stem cells by gene transfer

Autor: Rovira Ana, De Angioletti Maria, Camacho-Vanegas Ola, Liu Delong, Rosti Vittorio, Gallardo Humilidad, Notaro Rosario, Sadelain Michel, Luzzatto Lucio (A.R., M.D.A. have contributed equally to this work)

Publikováno v: Blood 96 (2000): 4111–4117.
info:cnr-pdr/source/autori:Rovira Ana, De Angioletti Maria, Camacho-Vanegas Ola, Liu Delong, Rosti Vittorio, Gallardo Humilidad, Notaro Rosario, Sadelain Michel, Luzzatto Lucio (A.R. and M.D.A. have contributed equally to this work)/titolo:Stable in vivo expression of glucose-6-phosphate dehydrogenase (G6PD) and rescue of G6PD deficiency in stem cells by gene transfer/doi:/rivista:Blood/anno:2000/pagina_da:4111/pagina_a:4117/intervallo_pagine:4111–4117/volume:96

Many mutations of the housekeeping gene encoding glucose 6-phosphate dehydrogenase (hG6PD) cause G6PD deficiency in humans. Some underlie severe forms of chronic non-spherocytic hemolytic anemia (CNSHA) for which there is no definitive treatment. By

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=cnr_________::d5591e0a91299441cb3f1ec3ef4230b6
https://publications.cnr.it/doc/232135