Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Cam T Ha"'
Publikováno v:
PLoS ONE, Vol 10, Iss 3, p e0122258 (2015)
We reported that microRNA-30c (miR-30c) plays a key role in radiation-induced human cell damage through an apoptotic pathway. Herein we further evaluated radiation-induced miR-30 expression and mechanisms of delta-tocotrienol (DT3), a radiation count
Externí odkaz:
https://doaj.org/article/7993b844ba9043078716cd0015b4878d
Autor:
Cam T Ha, Xiang-Hong Li, Dadin Fu, Maria Moroni, Carolyn Fisher, Robert Arnott, Venkataraman Srinivasan, Mang Xiao
Publikováno v:
PLoS ONE, Vol 9, Iss 10, p e109249 (2014)
We aim to develop a rapid, easy-to-use, inexpensive and accurate radiation dose-assessment assay that tests easily obtained samples (e.g., blood) to triage and track radiological casualties, and to evaluate the radioprotective and therapeutic effects
Externí odkaz:
https://doaj.org/article/5793a1e06ef24591a20f9f66070ec666
Publikováno v:
PLoS ONE, Vol 7, Iss 11, p e48700 (2012)
We recently demonstrated that a novel cell stress response gene REDD1 protects human fetal osteoblast cell line (hFOB) cells from γ-radiation-induced premature senescence. Here we show that levels of endogenous REDD1 are very low in human hematopoie
Externí odkaz:
https://doaj.org/article/ecd1a902bda446ba8bd19c6edfbc8c37
Publikováno v:
PLoS ONE, Vol 7, Iss 5, p e36604 (2012)
Radiotherapy is commonly used for cancer treatment. However, it often results in side effects due to radiation damage in normal tissue, such as bone marrow (BM) failure. Adult hematopoietic stem and progenitor cells (HSPC) reside in BM next to the en
Externí odkaz:
https://doaj.org/article/8641505b1aae4fc196953c6fb82b03dd
Publikováno v:
Radiation Research. 185:375-383
We have previously reported that circulating interleukin-18 (IL-18) can be used as a radiation biomarker in mice, minipigs and nonhuman primates. In this study, we further determined the serum levels of IL-18 binding protein (IL-18BP), a natural endo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7f25a8d665cb3907ae74899e105272a7
https://doi.org/10.1667/rr14238.1
https://doi.org/10.1667/rr14238.1
Publikováno v:
Apoptosis
We previously reported that microRNA-30 (miR-30) expression was initiated by radiation-induced proinflammatory factor IL-1β and NFkB activation in mouse and human hematopoietic cells. However, the downstream effectors of miR-30 and its specific role
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0000f895d87afc8bada68bac2a6f6c63
https://doi.org/10.1007/s10495-016-1238-1
https://doi.org/10.1007/s10495-016-1238-1
Autor:
Dadin Fu, Mang Xiao, Thomas B. Elliott, Vilmar Villa, Cam T. Ha, Mark H. Whitnall, Michael R. Landauer, Sanchita P. Ghosh, Xiang Hong Li, David L. Bolduc
Publikováno v:
Radiation Research. 180:649-657
We recently demonstrated that natural delta-tocotrienol (DT3) significantly enhanced survival in total-body irradiated (TBI) mice, and protected mouse bone marrow cells from radiation-induced damage through Erk activation-associated mTOR survival pat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a16ac8baf5bcd12e363115b81dfed606
https://doi.org/10.1667/rr13398.1
https://doi.org/10.1667/rr13398.1
Publikováno v:
Placenta
In primates and rodents, trophoblast cells synthesize and secrete into the maternal circulation a family of proteins known as pregnancy specific glycoproteins (PSG). The current study was undertaken to characterize the receptor for two members of the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d77ea99bb8c22049b7826c06d0363a18
Autor:
Julie A. Wu, Süleyman Ergün, Ster Irmak, Cam T. Ha, Felipe A. Lisboa, James Warren, Gabriela S. Dveksler, Anne M. Dizon
Publikováno v:
Biology of Reproduction
Previous studies suggest that human pregnancy specific beta-1-glycoproteins (PSGs) play immunomodulatory roles during pregnancy; however, other possible functions of PSGs have yet to be explored. We have observed that PSGs induce transforming growth
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3383a10daf6bdceca124c3e785beef7d
Publikováno v:
Biology of Reproduction. 79:1054-1061
Haemochorial placentation is a unique physiological process in which the fetal trophoblast cells remodel the maternal decidual spiral arteries to establish the fetoplacental blood supply. Pregnancy-specific glycoproteins (PSGs) are members of the car
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::10caaa62549e7149f2db787951bebb81
https://doi.org/10.1095/biolreprod.108.070268
https://doi.org/10.1095/biolreprod.108.070268