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pro vyhledávání: '"Cam Ha T Tran"'
Autor:
Pratish Thakore, Michael G Alvarado, Sher Ali, Amreen Mughal, Paulo W Pires, Evan Yamasaki, Harry AT Pritchard, Brant E Isakson, Cam Ha T Tran, Scott Earley
Publikováno v:
eLife, Vol 10 (2021)
Cerebral blood flow is dynamically regulated by neurovascular coupling to meet the dynamic metabolic demands of the brain. We hypothesized that TRPA1 channels in capillary endothelial cells are stimulated by neuronal activity and instigate a propagat
Externí odkaz:
https://doaj.org/article/7b23c918a6444d5fb49cd757a865a485
Publikováno v:
Communications Biology, Vol 7, Iss 1, Pp 1-10 (2024)
Abstract Dynamic changes in astrocyte Ca2+ are recognized as contributors to functional hyperemia, a critical response to increased neuronal activity mediated by a process known as neurovascular coupling (NVC). Although the critical role of glutamate
Externí odkaz:
https://doaj.org/article/342be4e2bf8f43a3b590b9a405461449
Publikováno v:
PLoS ONE, Vol 9, Iss 10, p e110475 (2014)
Two-photon laser scanning microscopy has revolutionized the ability to delineate cellular and physiological function in acutely isolated tissue and in vivo. However, there exist barriers for many laboratories to acquire two-photon microscopes. Additi
Externí odkaz:
https://doaj.org/article/268f5e69b13546b68c59222cda984f1c
Publikováno v:
Frontiers in Physiology, Vol 11 (2020)
Astrocytic Ca2+ fluctuations associated with functional hyperemia have typically been measured from large cellular compartments such as the soma, the whole arbor and the endfoot. The most prominent Ca2+ event is a large magnitude, delayed signal that
Externí odkaz:
https://doaj.org/article/d38c214116ab498ab0c4e0d3a275836e
Publikováno v:
JCI Insight, Vol 5, Iss 19 (2020)
Seizures can result in a severe hypoperfusion/hypoxic attack that causes postictal memory and behavioral impairments. However, neither postictal changes to microvasculature nor Ca2+ changes in key cell types controlling blood perfusion have been visu
Externí odkaz:
https://doaj.org/article/1887ad402b024477bcbfdef289570e19
Autor:
Cam Ha T. Tran, G. Campbell Teskey
Publikováno v:
Neuroglia. 2:36-47
Neurovascular coupling is a key control mechanism in cerebral blood flow (CBF) regulation. Importantly, this process was demonstrated to be affected in several neurological disorders, including epilepsy. Neurovascular coupling (NVC) is the basis for
Autor:
Cam Ha T. Tran
Publikováno v:
Neurophotonics. 9
Autor:
Shaun L. Sandow, Cam Ha T. Tran, Anil Zechariah, Bjørn Olav Hald, Michelle Sun Mi Kim, Maria Sancho, Ursula I. Tuor, Donald G. Welsh, Grant R. Gordon, Sergio Fabris
Publikováno v:
Arterioscler Thromb Vasc Biol
Cerebral arterial networks match blood flow delivery with neural activity. Neurovascular response begins with a stimulus and a focal change in vessel diameter, which by themselves is inconsequential to blood flow magnitude, until they spread and alte
Autor:
Cam Ha T, Tran
Publikováno v:
Neurophotonics. 9(2)