Zobrazeno 1 - 10
of 40
pro vyhledávání: '"Calwing, Liao"'
Autor:
Charles-Etienne Castonguay, Calwing Liao, Anouar Khayachi, Yumin Liu, Miranda Medeiros, Gabrielle Houle, Jay P. Ross, Patrick A. Dion, Guy A. Rouleau
Publikováno v:
npj Genomic Medicine, Vol 7, Iss 1, Pp 1-13 (2022)
Abstract Essential tremor (ET) is one of the most common movement disorders, affecting nearly 5% of individuals over 65 years old. Despite this, few genetic risk loci for ET have been identified. Recent advances in pharmacogenomics have previously be
Externí odkaz:
https://doaj.org/article/a039ede0ce6a42c794df849f2ee72262
Autor:
Calwing Liao, Veikko Vuokila, Hélène Catoire, Fulya Akçimen, Jay P. Ross, Cynthia V. Bourassa, Patrick A. Dion, Inge A. Meijer, Guy A. Rouleau
Publikováno v:
Communications Biology, Vol 5, Iss 1, Pp 1-6 (2022)
Calwing Liao and Veikko Vuokila et al. report a transcriptome-wide association study (TWAS) of Tourette’s Syndrome. They find increased expression of FLT3 in the dorsolateral prefrontal cortex and the lymphoblastoid cell lines in patients with Tour
Externí odkaz:
https://doaj.org/article/c55de6f7799640e488bf9c601ff989c6
Autor:
Qin He, Célia Jantac Mam-Lam-Fook, Julie Chaignaud, Charlotte Danset-Alexandre, Anton Iftimovici, Johanna Gradels Hauguel, Gabrielle Houle, Calwing Liao, ICAAR study group, Patrick A. Dion, Guy A. Rouleau, Oussama Kebir, Marie-Odile Krebs, Boris Chaumette
Publikováno v:
Translational Psychiatry, Vol 11, Iss 1, Pp 1-9 (2021)
Abstract Cognitive impairment is a core feature of schizophrenia which precedes the onset of full psychotic symptoms, even in the ultra-high-risk stage (UHR). Polygenic risk scores (PRS) can be computed for many psychiatric disorders and phenotyping
Externí odkaz:
https://doaj.org/article/175a1bb7257548a3b8336d9bb1081eb3
Autor:
Calwing Liao, Alexandre D. Laporte, Dan Spiegelman, Fulya Akçimen, Ridha Joober, Patrick A. Dion, Guy A. Rouleau
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-7 (2019)
A recent GWAS reported 12 genetic loci for attention deficit/hyperactivity disorder (ADHD). Here, Liao et al. perform transcriptomic imputation using these data and 12 brain-relevant tissues from GTEx and CMC to identify 9 genes associated with ADHD
Externí odkaz:
https://doaj.org/article/98989c48e5614c72b3a29f0f4c4ddced
Autor:
Calwing Liao, Faezeh Sarayloo, Veikko Vuokila, Daniel Rochefort, Fulya Akçimen, Simone Diamond, Gabrielle Houle, Alexandre D. Laporte, Dan Spiegelman, Qin He, Hélène Catoire, Patrick A. Dion, Guy A. Rouleau
Publikováno v:
Frontiers in Genetics, Vol 11 (2020)
Objective: Essential tremor (ET) is a common movement disorder that has a high heritability. A number of genetic studies have associated different genes and loci with ET, but few have investigated the biology of any of these genes. STK32B was signifi
Externí odkaz:
https://doaj.org/article/1b7dca9c79064eee9686d420cea20d75
Autor:
Fulya Akçimen, Jay P. Ross, Cynthia V. Bourassa, Calwing Liao, Daniel Rochefort, Maria Thereza Drumond Gama, Marie-Josée Dicaire, Orlando G. Barsottini, Bernard Brais, José Luiz Pedroso, Patrick A. Dion, Guy A. Rouleau
Publikováno v:
Frontiers in Genetics, Vol 10 (2019)
A biallelic pentanucleotide expansion in the RFC1 gene has been reported to be a common cause of late-onset ataxia. In the general population, four different repeat conformations are observed: wild type sequence AAAAG (11 repeats) and longer expansio
Externí odkaz:
https://doaj.org/article/3196f93a42ed4362ba5f64f66a72f8a3
Autor:
Calwing Liao, Mariana Moyses-Oliveira, Celine E.F. De Esch, Riya Bhavsar, Xander Nuttle, Aiqun Li, Alex Yu, Nicholas D. Burt, Serkan Erdin, Jack M. Fu, Minghui Wang, Theodore Morley, Lide Han, Patrick A. Dion, Guy A. Rouleau, Bin Zhang, Kristen J. Brennand, Michael E. Talkowski, Douglas M. Ruderfer
Publikováno v:
Cell Genom
Autism spectrum disorder (ASD) is a heritable neurodevelopmental disorder characterized by deficits in social interactions and communication. Protein-altering variants in many genes have been shown to contribute to ASD; however, understanding the con
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d0728edf9449fbcded495c4be38ace09
https://europepmc.org/articles/PMC10112287/
https://europepmc.org/articles/PMC10112287/
Autor:
Jay P. Ross, Fulya Akçimen, Calwing Liao, Karina Kwan, Daniel E. Phillips, Zoe Schmilovich, Dan Spiegelman, Angela Genge, Nicolas Dupré, Patrick A. Dion, Sali M.K. Farhan, Guy A. Rouleau
The genetic etiology of ALS includes few rare, large-effect variants and potentially many common, small-effect variants per case. The genetic risk liability for ALS might require a threshold comprised of a certain amount of variants. Here, we tested
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7e5e9c089515d4c08200a6ffa41b3e2a
https://doi.org/10.1101/2022.08.11.22278628
https://doi.org/10.1101/2022.08.11.22278628
Autor:
Austen J. Milnerwood, Boris Chaumette, Patrick A. Dion, Anouar Khayachi, Guy A. Rouleau, Ariel R. Ase, Philippe Séguéla, Calwing Liao, Martin Alda, Anusha Kamesh, Lenka Schorova, Naila Kuhlmann
Publikováno v:
Journal of Psychiatry and Neuroscience
Journal of Psychiatry and Neuroscience, Canadian Medical Association, 2021, 46 (3), pp.E402-E414. ⟨10.1503/jpn.200185⟩
Journal of Psychiatry & Neuroscience : JPN
Journal of Psychiatry and Neuroscience, Canadian Medical Association, 2021, 46 (3), pp.E402-E414. ⟨10.1503/jpn.200185⟩
Journal of Psychiatry & Neuroscience : JPN
International audience; Background: Bipolar disorder is characterized by cyclical alternation between mania and depression, often comorbid with psychosis and suicide. Compared with other medications, the mood stabilizer lithium is the most effective
Autor:
Jay P. Ross, Fulya Akcimen, Calwing Liao, Dan Spiegelman, Ben Weisburd, Nicolas Dupré, Patrick A. Dion, Guy A. Rouleau, Sali M. K. Farhan
Lowered expression of STMN2 is associated with TDP-43 pathology in amyotrophic lateral sclerosis (ALS). Recently, the number of dinucleotide CA repeats in an intron of the STMN2 gene was reported to be associated with increased risk for ALS. Here, we
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e2dd993fbcbf659b85bbf39db7aa0bed
https://doi.org/10.1101/2022.04.30.22273566
https://doi.org/10.1101/2022.04.30.22273566