Výsledky vyhledávání - "Calvin R.K. Blaschke"

Analysis of N-linked Glycan Alterations in Tissue and Serum Reveals Promising Biomarkers for Intrahepatic Cholangiocarcinoma

Autor: Shaaron Ochoa-Rios, Calvin R.K. Blaschke, Mengjun Wang, Kendell D. Peterson, Andrew DelaCourt, Stéphane Elie Grauzam, David Lewin, Peggi Angel, Lewis R. Roberts, Richard Drake, Anand S. Mehta

Publikováno v: Cancer Research Communications. 3:383-394

There is an urgent need for the identification of reliable prognostic biomarkers for patients with intrahepatic cholangiocarcinoma (iCCA) and alterations in N-glycosylation have demonstrated an immense potential to be used as diagnostic strategies fo

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::e9c0a29666ffdeac98fe61d9ec5f63f8
https://doi.org/10.1158/2767-9764.crc-22-0422

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Supplementary Figure SF4 from Analysis of N-linked Glycan Alterations in Tissue and Serum Reveals Promising Biomarkers for Intrahepatic Cholangiocarcinoma

Autor: Anand S. Mehta, Richard Drake, Lewis R. Roberts, Peggi Angel, David Lewin, Stéphane Elie Grauzam, Andrew DelaCourt, Kendell D. Peterson, Mengjun Wang, Calvin R.K. Blaschke, Shaaron Ochoa-Rios

A. Scatterplots and correlations between N-glycans of interest (1339, 1257, 2158) and clinical information available (ALT, AST, ALK, and AFP). B. Multivariate model-Multiple logistic regression in CCA and PSC serum samples (n=40). Model 1: three N-gl

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::695982313324f41d3439f7bb59629bf7
https://doi.org/10.1158/2767-9764.22546717

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Supplementary Figure SF3 from Analysis of N-linked Glycan Alterations in Tissue and Serum Reveals Promising Biomarkers for Intrahepatic Cholangiocarcinoma

Autor: Anand S. Mehta, Richard Drake, Lewis R. Roberts, Peggi Angel, David Lewin, Stéphane Elie Grauzam, Andrew DelaCourt, Kendell D. Peterson, Mengjun Wang, Calvin R.K. Blaschke, Shaaron Ochoa-Rios

A. Relative contribution of each serum-glycan (left) and TMA-glycan (right) in the first and second principal components. The size and color of the circle represent a higher contribution of the glycan to the respective Dim. (Dimension). B. Three N-gl

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2a25c87150f941581dd6190086fc2776
https://doi.org/10.1158/2767-9764.22546720.v1

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Supplementary Figure SF2 from Analysis of N-linked Glycan Alterations in Tissue and Serum Reveals Promising Biomarkers for Intrahepatic Cholangiocarcinoma

Autor: Anand S. Mehta, Richard Drake, Lewis R. Roberts, Peggi Angel, David Lewin, Stéphane Elie Grauzam, Andrew DelaCourt, Kendell D. Peterson, Mengjun Wang, Calvin R.K. Blaschke, Shaaron Ochoa-Rios

Patient demographics for A. TMA 1 and B. TMA 2. C. Patient demographics for serum cohort. ALT (Alanine transaminase), AST (aspartate aminotransferase), AFP (Alpha-fetoprotein), and ALP (Alkaline phosphatase). Other liver diseases include nonalcoholic

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6dd3c35ae5936a61f8568212a94f5697
https://doi.org/10.1158/2767-9764.22546723.v1

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Data from Analysis of N-linked Glycan Alterations in Tissue and Serum Reveals Promising Biomarkers for Intrahepatic Cholangiocarcinoma

Autor: Anand S. Mehta, Richard Drake, Lewis R. Roberts, Peggi Angel, David Lewin, Stéphane Elie Grauzam, Andrew DelaCourt, Kendell D. Peterson, Mengjun Wang, Calvin R.K. Blaschke, Shaaron Ochoa-Rios

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1bacd7bdafc1ccde6b69be06e3d7f342
https://doi.org/10.1158/2767-9764.c.6551233.v1

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Supplementary Table ST2 from Analysis of N-linked Glycan Alterations in Tissue and Serum Reveals Promising Biomarkers for Intrahepatic Cholangiocarcinoma

Autor: Anand S. Mehta, Richard Drake, Lewis R. Roberts, Peggi Angel, David Lewin, Stéphane Elie Grauzam, Andrew DelaCourt, Kendell D. Peterson, Mengjun Wang, Calvin R.K. Blaschke, Shaaron Ochoa-Rios

Lists individual N-glycans, ALT (Alanine transaminase), AST (aspartate aminotransferase), ALK (Alkaline phosphatase), and AFP (Alpha-fetoprotein) of analysis to differentiate patients with iCCA from PSC. 1Possible biomarkers 2n: number of total patie

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6fbd7dfa4dc789a14fb232d6b97ff804
https://doi.org/10.1158/2767-9764.22546708.v1

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Supplementary Figure SF1 from Analysis of N-linked Glycan Alterations in Tissue and Serum Reveals Promising Biomarkers for Intrahepatic Cholangiocarcinoma

Autor: Anand S. Mehta, Richard Drake, Lewis R. Roberts, Peggi Angel, David Lewin, Stéphane Elie Grauzam, Andrew DelaCourt, Kendell D. Peterson, Mengjun Wang, Calvin R.K. Blaschke, Shaaron Ochoa-Rios

Hematoxylin & Eosin (H&E) staining of A. Intrahepatic Cholangiocarcinoma (iCCA) tissue, 10x (right) and 40x (left) magnification images from respective areas of the tissue, and B. Hepatocellular Carcinoma (HCC) tissue, 10x magnification images from r

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2d89a8473a2cf648b0ecb04bbdb90c34
https://doi.org/10.1158/2767-9764.22546726.v1

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Supplementary Figure SF5 from Analysis of N-linked Glycan Alterations in Tissue and Serum Reveals Promising Biomarkers for Intrahepatic Cholangiocarcinoma

Autor: Anand S. Mehta, Richard Drake, Lewis R. Roberts, Peggi Angel, David Lewin, Stéphane Elie Grauzam, Andrew DelaCourt, Kendell D. Peterson, Mengjun Wang, Calvin R.K. Blaschke, Shaaron Ochoa-Rios

Relative intensity quantification of all N-glycans identified in serum (left row) and tissue (right row) analysis. Red font labeling for N-glycans follows the same trend between serum and tissue.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0e57cabfdfed502c16e984b8b430a188
https://doi.org/10.1158/2767-9764.22546714

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