Výsledky vyhledávání - "Calvin Neace"

Akademický článek

Trichomonosis, a common curable STI, and prostate carcinogenesis--a proposed molecular mechanism.

Autor: Siobhan Sutcliffe, Calvin Neace, Nancy S Magnuson, Raymond Reeves, J F Alderete

Publikováno v: PLoS Pathogens, Vol 8, Iss 8, p e1002801 (2012)

Externí odkaz: https://doaj.org/article/b7dc114cadc04823855a4805805ab3e5

Elimination of tucatinib, a small molecule kinase inhibitor of HER2, is primarily governed by CYP2C8 enantioselective oxidation of gem-dimethyl

Autor: Hao Sun, Kristen A. Cardinal, Larry Wienkers, Alice Chin, Vineet Kumar, Calvin Neace, Clark Henderson, Christopher J. Endres, Ariel Topletz-Erickson, Kelly Regal, Alex Vo, Stephen C. Alley, Anthony J. Lee

Publikováno v: Cancer chemotherapy and pharmacology. 89(6)

Tucatinib, a small molecule for the treatment of metastatic HER2-positive breast cancer, was extensively metabolized in humans to multiple oxidative metabolites. To fully understand the elimination and biotransformation pathways of tucatinib, we inve

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b18ec46a252316d2348fe244993f0977
https://pubmed.ncbi.nlm.nih.gov/35435471

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