Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Calvin G. Ludwig"'
Publikováno v:
International Journal of Molecular Sciences, Vol 20, Iss 2, p 442 (2019)
Arf GTPase-activating proteins (Arf GAPs) control the activity of ADP-ribosylation factors (Arfs) by inducing GTP hydrolysis and participate in a diverse array of cellular functions both through mechanisms that are dependent on and independent of the
Externí odkaz:
https://doaj.org/article/299da6b13f15465ab33b83ddbe4e5238
Autor:
Megan L. Insco, Brian J. Abraham, Sara J. Dubbury, Ines H. Kaltheuner, Sofia Dust, Constance Wu, Kevin Y. Chen, David Liu, Stanislav Bellaousov, Anna M. Cox, Benjamin J. E. Martin, Tongwu Zhang, Calvin G. Ludwig, Tania Fabo, Rodsy Modhurima, Dakarai E. Esgdaille, Telmo Henriques, Kevin M. Brown, Stephen J. Chanock, Matthias Geyer, Karen Adelman, Phillip A. Sharp, Richard A. Young, Paul L. Boutz, Leonard I. Zon
Publikováno v:
Science
RNA surveillance pathways detect and degrade defective transcripts to ensure RNA fidelity. We found that disrupted nuclear RNA surveillance is oncogenic. Cyclin-dependent kinase 13 ( CDK13 ) is mutated in melanoma, and patient-mutated CDK13 accelerat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::56a0b2b1bcb20159e50e884d8f56a8dd
https://doi.org/10.1126/science.abn7625
https://doi.org/10.1126/science.abn7625
Publikováno v:
World Neurosurgery. 159:e8-e22
Background Radiomics is a powerful tool for automatic extraction of morphologic features, but when applied to cerebral aneurysms is inferior to established descriptors in classifying rupture status. We sought a strategy to recover neck orientation an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::59fdd6057d9480639ad9b110d1f9877d
https://doi.org/10.1016/j.wneu.2021.11.038
https://doi.org/10.1016/j.wneu.2021.11.038
Publikováno v:
Journal of NeuroInterventional Surgery. 13:755-761
BackgroundMorphological differences between ruptured and unruptured cerebral aneurysms represent a focus of neuroimaging researchfor understanding the mechanisms of aneurysmal rupture. We evaluated the performance of Radiomics derived morphological f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a4dea64a66d95c2d661a7b500790b556
https://doi.org/10.1136/neurintsurg-2020-016808
https://doi.org/10.1136/neurintsurg-2020-016808
Autor:
Calvin G. Ludwig, Penny Liu, Michael J. Yang, James Kryzanski, T. Jayde Nail, Ron I. Riesenburger, Jeffrey M Breton
Publikováno v:
Journal of neurosurgery. Spine. 36(4)
OBJECTIVE Spinal anesthesia (SA) is an alternative to general anesthesia (GA) for lumbar spine surgery, including complex instrumented fusion, although there are relatively few outcome data available. The authors discuss their experience using SA in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::23280862328f4a575eac12e921bcea05
https://pubmed.ncbi.nlm.nih.gov/34740182
https://pubmed.ncbi.nlm.nih.gov/34740182
Autor:
Phillip A. Sharp, Chen Ky, Fabo T, Boutz Pl, Sofia Dust, Calvin G Ludwig, Karen Adelman, Matthias Geyer, Dianbo Liu, Brian J. Abraham, Stanislav Bellaousov, Carl Wu, Insco Ml, Leonard I. Zon, Telmo Henriques, Sara J. Dubbury, Richard A. Young
Transcriptional Cyclin Dependent Kinases modulate RNA Polymerase II function to impact gene expression. Here, we show that CDK13 is mutated in 4% of patient melanomas and mutation or downregulation is associated with poor overall survival. Mutant CDK
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::595dcc3f8fc50c7616838d3a4340c0fe
Publikováno v:
International Journal of Molecular Sciences
International Journal of Molecular Sciences, Vol 20, Iss 2, p 442 (2019)
International Journal of Molecular Sciences, Vol 20, Iss 2, p 442 (2019)
Arf•GTPase-activating proteins (Arf•GAPs) control the activity of ADP-ribosylation factors (Arfs) by inducing GTP hydrolysis and participate in a diverse array of cellular functions both through mechanisms that are dependent on and independent of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::671943d0b8b8a41cd7c9ed6138aa5ffc
https://pubmed.ncbi.nlm.nih.gov/30669557
https://pubmed.ncbi.nlm.nih.gov/30669557