Zobrazeno 1 - 10
of 430
pro vyhledávání: '"Calum Macaulay"'
Autor:
Ali Silver, Cheryl Ho, Qian Ye, Jianjun Zhang, Ian Janzen, Jessica Li, Montgomery Martin, Lang Wu, Ying Wang, Stephen Lam, Calum MacAulay, Barbara Melosky, Ren Yuan
Publikováno v:
Current Oncology, Vol 30, Iss 6, Pp 5546-5559 (2023)
Health Canada approved pembrolizumab in the first-line setting for advanced non-small-cell lung cancer with PD-L1 ≥ 50% and no EGFR/ALK aberration. The keynote 024 trial showed 55% of such patients progress with pembrolizumab monotherapy. We propos
Externí odkaz:
https://doaj.org/article/d7ca249cc3e24802aba0ecf2c083cf39
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 11, Iss Suppl 1 (2023)
Externí odkaz:
https://doaj.org/article/9d0019073ec3431da9e11116c999c095
Fiber-Based Polarization Diversity Detection for Polarization-Sensitive Optical Coherence Tomography
Autor:
Hamid Pahlevaninezhad, Anthony M. D. Lee, Lucas Cahill, Stephen Lam, Calum MacAulay, Pierre Lane
Publikováno v:
Photonics, Vol 1, Iss 4, Pp 283-295 (2014)
We present a new fiber-based polarization diversity detection (PDD) scheme for polarization sensitive optical coherence tomography (PSOCT). This implementation uses a new custom miniaturized polarization-maintaining fiber coupler with single mode (SM
Externí odkaz:
https://doaj.org/article/0c6b2a87ce88450dae51d5a5b7bad881
Autor:
Gerald Li, Martial Guillaud, Jean LeRiche, Annette McWilliams, Adi Gazdar, Stephen Lam, Calum MacAulay
Publikováno v:
Analytical Cellular Pathology, Vol 35, Iss 3, Pp 187-201 (2012)
Background: Despite the benefits of early lung cancer detection, no effective strategy for early screening and treatment exists, partly due to a lack of effective surrogate biomarkers. Our novel sputum biomarker, the Combined Score (CS), uses automat
Externí odkaz:
https://doaj.org/article/f7cb1ea7df3a41d9abc66f73160fb2f9
Autor:
Julie M. Kneller, Thomas Ehlen, Jasenka P. Matisic, Dianne Miller, Dirk Van Niekerk, Wan L. Lam, Marco Marra, Rebecca Richards-Kortum, Michelle Follen, Calum MacAulay, Steven J.M. Jones
Publikováno v:
Biomarker Insights, Vol 2, Pp 447-461 (2007)
Sixteen longSAGE libraries from four different clinical stages of cervical intraepithelial neoplasia have enabled us to identify novel cell-surface biomarkers indicative of CIN stage. By comparing gene expression profiles of cervical tissue at early
Externí odkaz:
https://doaj.org/article/5881b76893ab402d9f5f6c6f6cfc8a65
Publikováno v:
Cellular Oncology, Vol 26, Iss 3, Pp 101-117 (2004)
Aims: Optical technologies have shown some promise for improving the care of cervical neoplasia. We are currently evaluating fluorescence and reflectance spectroscopy and quantitative cyto‐histopathology for cervical neoplasia screening and diagnos
Externí odkaz:
https://doaj.org/article/c71fc01848c9474fa2476165920c71c9
Autor:
Martial Guillaud, Dennis Cox, Anais Malpica, Gregg Staerkel, Jasenka Matisic, Dirk Van Niekirk, Karen Adler‐Storthz, Neal Poulin, Michele Follen, Calum MacAulay
Publikováno v:
Cellular Oncology, Vol 26, Iss 1-2, Pp 31-43 (2004)
Objectives: As part a Program Project to evaluate emerging optical technologies for cervical neoplasia, our group is performing quantitative histopathological analysis of biopsies from 1800 patients. Several methodological issues have arisen with res
Externí odkaz:
https://doaj.org/article/e7c498c79b9a40ed9c05f59e2b1af593
Publikováno v:
Cellular Oncology, Vol 26, Iss 5-6, Pp 319-327 (2004)
A novel optical computed‐tomographic microscope has been developed allowing quantitative three‐dimensional (3D) imaging and analysis of fixed pathological material. Rather than a conventional two‐dimensional (2D) image, the instrument produces
Externí odkaz:
https://doaj.org/article/658700e76b33424ea9ae55467977672f
Publikováno v:
Analytical Cellular Pathology, Vol 25, Iss 2, Pp 95-102 (2003)
Malignancy associated changes (MAC) can be defined as subtle morphological and physiologic changes that are found in ostensibly normal cells of patients harboring malignant disease. It has been postulated that MAC have a potential to become a useful
Externí odkaz:
https://doaj.org/article/852c990e7fc148668968b44d9b175857
Autor:
Richard Swartz, Loyd West, Iouri Boiko, Anais Malpica, Calum MacAulay, Anita Carraro, Martial Guillaud, Dennis Cox, Michele Follen
Publikováno v:
Analytical Cellular Pathology, Vol 25, Iss 4, Pp 193-200 (2003)
This is a methodological study exploring the use of quantitative histopathology applied to the cervix to discriminate between normal and cancerous (consisting of adenocarcinoma and adenocarcinoma in situ) tissue samples. The goal is classifying tissu
Externí odkaz:
https://doaj.org/article/abcdb7c9f7584543acbec84fed2ec7d6