Zobrazeno 1 - 10
of 52
pro vyhledávání: '"Calpurnia Jayakumar"'
Publikováno v:
Mediators of Inflammation, Vol 2014 (2014)
Acute kidney injury (AKI) is a common problem in the hospital setting and intensive care unit. Despite improved understanding, there are no effective therapies available to treat AKI. A large body of evidence strongly suggests that ischemia reperfusi
Externí odkaz:
https://doaj.org/article/24a5fa3e1dc3433895c5c2834b5a0237
Autor:
Lidia Lewandowska, Joanna Matuszkiewicz-Rowińska, Calpurnia Jayakumar, Urszula Oldakowska-Jedynak, Stephen Looney, Michalina Galas, Małgorzata Dutkiewicz, Marek Krawczyk, Ganesan Ramesh
Publikováno v:
PLoS ONE, Vol 9, Iss 10, p e107898 (2014)
Acute kidney injury (AKI) is a serious complication after liver transplantation. Currently there are no validated biomarkers available for early diagnosis of AKI. The current study was carried out to determine the usefulness of the recently identifie
Externí odkaz:
https://doaj.org/article/64246427250742e5ab1e164b1a8aae52
Semaphorin 3A is a new early diagnostic biomarker of experimental and pediatric acute kidney injury.
Autor:
Calpurnia Jayakumar, Punithavathi Ranganathan, Prasad Devarajan, Catherine D Krawczeski, Stephen Looney, Ganesan Ramesh
Publikováno v:
PLoS ONE, Vol 8, Iss 3, p e58446 (2013)
Semaphorin 3A is a secreted protein that regulates cell motility and attachment in axon guidance, vascular growth, immune cell regulation and tumor progression. However, nothing is known about its role in kidney pathophysiology. Here, we determined w
Externí odkaz:
https://doaj.org/article/708b34edf95f41d7a6cb35779ce955be
Publikováno v:
PLoS ONE, Vol 6, Iss 10, p e26776 (2011)
Netrin-1 is a laminin-related secreted protein, is highly induced after tissue injury, and may serve as a marker of injury. However, the regulation of netrin-1 production is not unknown. Current study was carried out in mouse and mouse kidney cell li
Externí odkaz:
https://doaj.org/article/4b7195e9161647dbad58eddf0144d4a0
Autor:
Calpurnia Jayakumar, Riyaz Mohamed, Feng Chen, David W. Stepp, Ganesan Ramesh, Ron T. Gansevoort, David Fulton
Publikováno v:
Journal of the American Society of Nephrology, 27(3), 745-765. AMER SOC NEPHROLOGY
Diabetes is the leading cause of kidney failure, accounting for >45% of new cases of dialysis. Diabetic nephropathy is characterized by inflammation, fibrosis, and oxidant stress, pathologic features that are shared by many other chronic inflammatory
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e3e126a9e4f5f7c4ca43f3f5e2b147cb
https://research.rug.nl/en/publications/a054ebc6-0e9b-4ef9-8268-cb454d45df63
https://research.rug.nl/en/publications/a054ebc6-0e9b-4ef9-8268-cb454d45df63
Autor:
Ganesan Ramesh, Ferdau L. Nauta, Ron T. Gansevoort, Neal L. Weintraub, Michael W. Brands, Riyaz Mohamed, Calpurnia Jayakumar, Punithavathi Ranganathan
Publikováno v:
Journal of Molecular Medicine, 92(12), 1245-1256. SPRINGER HEIDELBERG
Semaphorin 3A (sema3A) was recently identified as an early diagnostic biomarker of acute kidney injury. However, its role as a biomarker and/or mediator of chronic kidney disease (CKD) related to diabetic nephropathy is unknown. We examined the expre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::979f02ace02570ea5eac52e3201ed815
https://doi.org/10.1007/s00109-014-1209-3
https://doi.org/10.1007/s00109-014-1209-3
Autor:
Ganesan Ramesh, Calpurnia Jayakumar, Neal L. Weintraub, Riyaz Mohamed, Punithavathi Ranganathan
Publikováno v:
American Journal of Physiology-Renal Physiology. 307:F183-F194
Recent studies show that guidance molecules that are known to regulate cell migration during development may also play an important role in adult pathophysiologic states. One such molecule, semaphorin3A (sema3A), is highly expressed after acute kidne
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9f7c649def9f7ed819b307a895f9efd4
https://doi.org/10.1152/ajprenal.00177.2014
https://doi.org/10.1152/ajprenal.00177.2014
Autor:
Roberto Pontremoli, Ganesan Ramesh, Debora Garneri, Calpurnia Jayakumar, Francesca Viazzi, Giovanna Leoncini
Publikováno v:
Journal of Nephrology. 28:315-320
Semaphorins are guidance proteins implicated in several processes such as angiogenesis, organogenesis, cell migration, and cytokine release. Experimental studies showed that semaphorin-3a (SEMA3A) administration induces transient massive proteinuria,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6ccf848c593191c733bd0b92ee70966f
https://doi.org/10.1007/s40620-014-0097-5
https://doi.org/10.1007/s40620-014-0097-5
Publikováno v:
Journal of Cellular and Molecular Medicine
The netrin-1 administration or overexpression is known to protect colon from acute colitis. However, the receptor that mediates netrin-1 protective activities in the colon during colitis remains unknown. We tested the hypothesis that UNC5B receptor i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3cbd14fe3578167fe2504e5d02ee2266
https://doi.org/10.1111/jcmm.12280
https://doi.org/10.1111/jcmm.12280
Autor:
Maribeth H. Johnson, Calpurnia Jayakumar, Henk J. G. Bilo, Stephan J. L. Bakker, Ron T. Gansevoort, Ferdau L. Nauta, Ganesan Ramesh
Publikováno v:
Journal of Nephrology, 27(2), 151-157. SPRINGER HEIDELBERG
Netrin-1 was recently identified as an early diagnostic biomarker of chronic kidney disease (CKD) in an experimental animal model. However, its usefulness for early diagnosis of CKD in humans is unknown. The current study evaluated whether netrin-1 i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e5613e5fbf409cf5b7c793a0d752ce25
https://doi.org/10.1007/s40620-014-0055-2
https://doi.org/10.1007/s40620-014-0055-2