Zobrazeno 1 - 10
of 32
pro vyhledávání: '"Callum M. Zgierski-Johnston"'
Autor:
Ramona Emig, Callum M. Zgierski-Johnston, Friedhelm Beyersdorf, Bartosz Rylski, Ursula Ravens, Wilfried Weber, Peter Kohl, Maximilian Hörner, Rémi Peyronnet
Publikováno v:
Frontiers in Physiology, Vol 10 (2020)
Fibrosis is associated with aging and many cardiac pathologies. It is characterized both by myofibroblast differentiation and by excessive accumulation of extracellular matrix proteins. Fibrosis-related tissue remodeling results in significant change
Externí odkaz:
https://doaj.org/article/c7d0df74de5f42d3a032870173bb4551
Publikováno v:
Cells, Vol 10, Iss 11, p 2923 (2021)
Cardiac electrophysiological disorders, in particular arrhythmias, are a key cause of morbidity and mortality throughout the world. There are two basic requirements for arrhythmogenesis: an underlying substrate and a trigger. Altered conduction veloc
Externí odkaz:
https://doaj.org/article/8951c843efde4660813d828e9dd29b95
Autor:
Ramona A. Kopton, Jonathan S. Baillie, Sara A. Rafferty, Robin Moss, Callum M. Zgierski-Johnston, Sergey V. Prykhozhij, Matthew R. Stoyek, Frank M. Smith, Peter Kohl, T. Alexander Quinn, Franziska Schneider-Warme
Publikováno v:
Frontiers in Physiology, Vol 9 (2018)
During the last decade, optogenetics has emerged as a paradigm-shifting technique to monitor and steer the behavior of specific cell types in excitable tissues, including the heart. Activation of cation-conducting channelrhodopsins (ChR) leads to mem
Externí odkaz:
https://doaj.org/article/7aa61847c504434382bca44f3b3b283e
Autor:
Ramona Emig, Wiebke Knodt, Mario J. Krussig, Callum M. Zgierski-Johnston, Oliver Gorka, Olaf Groß, Peter Kohl, Ursula Ravens, Rémi Peyronnet
Publikováno v:
Cells, Vol 10, Iss 3, p 663 (2021)
The mechanical environment of cardiac cells changes continuously and undergoes major alterations during diseases. Most cardiac diseases, including atrial fibrillation, are accompanied by fibrosis which can impair both electrical and mechanical functi
Externí odkaz:
https://doaj.org/article/b3581d9491e344ef956e7aee8080cc9a
Publikováno v:
Methods in Molecular Biology ISBN: 9781071630518
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::da758ad7d6a3f3cab292cb5368c5f5eb
https://doi.org/10.1007/978-1-0716-3052-5_27
https://doi.org/10.1007/978-1-0716-3052-5_27
Autor:
Ramona Emig, Callum M. Zgierski-Johnston, Andrew J. Taberner, Rémi Peyronnet, Martyn P. Nash, Peter Kohl, Viviane Timmermann
Publikováno v:
Biophysical Reviews
Passive mechanical tissue properties are major determinants of myocardial contraction and relaxation and, thus, shape cardiac function. Tightly regulated, dynamically adapting throughout life, and affecting a host of cellular functions, passive tissu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9354b2311e98435e7fb609cf6b8ad4bc
https://doi.org/10.1007/s12551-021-00838-1
https://doi.org/10.1007/s12551-021-00838-1
Autor:
Mary K. Morphew, Eileen T. O'Toole, Eva A. Rog-Zielinska, Leonardo Sacconi, Callum M. Zgierski-Johnston, Andreas Hoenger, Marina Scardigli, Joachim Greiner, Rémi Peyronnet, Peter Kohl, Josef Madl
Publikováno v:
Circulation Research
Supplemental Digital Content is available in the text.
Rationale: The sarcolemma of cardiomyocytes contains many proteins that are essential for electromechanical function in general, and excitation-contraction coupling in particular. The distri
Rationale: The sarcolemma of cardiomyocytes contains many proteins that are essential for electromechanical function in general, and excitation-contraction coupling in particular. The distri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2c92cb005e4702b1187be84c285e5fb4
https://doi.org/10.1161/circresaha.120.317266
https://doi.org/10.1161/circresaha.120.317266
Autor:
Falk Barz, Callum M. Zgierski-Johnston, Patrick Ruther, Oliver Paul, Eva A. Rog-Zielinska, Marbely C Fernández, Suleman Ayub, Peter Kohl
Publikováno v:
Progress in Biophysics and Molecular Biology
Optogenetics enables cell-type specific monitoring and actuation via light-activated proteins. In cardiac research, expressing light-activated depolarising ion channels in cardiomyocytes allows optical pacing and defibrillation. Previous studies larg
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9ba015c99d606a08c1c170d61f21ea18
https://doi.org/10.1016/j.pbiomolbio.2019.11.004
https://doi.org/10.1016/j.pbiomolbio.2019.11.004
Publikováno v:
Advances in experimental medicine and biology. 1293
The heart is a complex multicellular organ comprising both cardiomyocytes (CM), which make up the majority of the cardiac volume, and non-myocytes (NM), which represent the majority of cardiac cells. CM drive the pumping action of the heart, triggere
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::837bc36d0cd17f43626c9e5215994f1e
https://pubmed.ncbi.nlm.nih.gov/33398827
https://pubmed.ncbi.nlm.nih.gov/33398827
Publikováno v:
Advances in Experimental Medicine and Biology ISBN: 9789811587627
The heart is a complex multicellular organ comprising both cardiomyocytes (CM), which make up the majority of the cardiac volume, and non-myocytes (NM), which represent the majority of cardiac cells. CM drive the pumping action of the heart, triggere
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f3ffe9d09aa1ec85da743bbeb64a0194
https://doi.org/10.1007/978-981-15-8763-4_24
https://doi.org/10.1007/978-981-15-8763-4_24