Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Callum M. Johnston"'
Autor:
Amy S. Garrett, Ming Cheuk, Amir HajiRassouliha, Callum M. Johnston, Bryan P. Ruddy, Emily J. Lam Po Tang, Kenneth Tran, Alexander J. Anderson, Jarrah M. Dowrick, Poul M. F. Nielsen, June-Chiew Han, Toan Pham, Andrew J. Taberner, Denis S. Loiselle
Publikováno v:
IEEE Instrumentation & Measurement Magazine. 22:10-16
Muscle is an amazing natural thermodynamic engine that converts chemical energy into mechanical work. Each muscle twitch is ‘sparked’ by an electrically-released pulse of calcium ions, which trigger force-development and cell shortening, at the c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2d9d54b9465d881ab5211e105bb72821
https://doi.org/10.1109/mim.2019.8674628
https://doi.org/10.1109/mim.2019.8674628
Autor:
Andrew J. Taberner, Callum M. Johnston, June-Chiew Han, Denis S. Loiselle, Poul M. F. Nielsen
Publikováno v:
American Journal of Physiology-Heart and Circulatory Physiology. 310:H311-H325
The contraction of muscle is characterized by the development of force and movement (mechanics) together with the generation of heat (metabolism). Heat represents that component of the enthalpy of ATP hydrolysis that is not captured by the microscopi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b7023beebefb003da63ee0239d170d7a
https://doi.org/10.1152/ajpheart.00569.2015
https://doi.org/10.1152/ajpheart.00569.2015
Autor:
Callum M. Johnston, Eike M. Wülfers, Peter Kohl, Thomas Knöpfel, Torsten Houwaart, Franziska Schneider-Warme, Eva A. Rog-Zielinska, Roland Nitschke, Angela Naumann, Urszula Siedlecka
In optogenetics, light-activated proteins are used to monitor and modulate cellular behaviour with light. Combining genetic targeting of distinct cellular populations with defined patterns of optical stimulation enables one to study specific cell cla
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d9133370cb7fb938ac6894dcd7710e25
http://hdl.handle.net/10044/1/54812
http://hdl.handle.net/10044/1/54812
Publikováno v:
I2MTC
Many calorimetric sensing applications, such as measurement of heat exchange in chemical reactions or of the heat production of biological specimens, require high-resolution temperature sensors suitable for use at or near room temperature. We have de
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ad7d305faff0a703152c0d9e8a0a411b
https://doi.org/10.1109/i2mtc.2017.7969857
https://doi.org/10.1109/i2mtc.2017.7969857
Autor:
Poul M. F. Nielsen, Callum M. Johnston, Denis S. Loiselle, June-Chiew Han, Andrew J. Taberner, Ming L. Cheuk
Publikováno v:
EMBC
Heat liberated from isolated cardiac muscle has been used to inform us of thermo-mechanical processes that occur during a contraction. However, for comparisons between different samples to be useful, the heat output needs to be normalized to volume.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d5e721be889588adca4f2bd6445c214a
https://pubmed.ncbi.nlm.nih.gov/28268921
https://pubmed.ncbi.nlm.nih.gov/28268921
Publikováno v:
International Journal on Smart Sensing and Intelligent Systems, Vol 7, Iss 5 (2014)
Very high resolution power sensors are required for measuring the rate of heat production (~10 μW) of small samples of heart muscle (rat cardiac trabeculae, ~2 mm long and ~200 μm diameter). In this paper, we examine the design criteria for thermop
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8638b8d6bda29a6a38ac5ef01fcb8f7b
https://doi.org/10.21307/ijssis-2019-082
https://doi.org/10.21307/ijssis-2019-082
Autor:
Eva A, Rog-Zielinska, Callum M, Johnston, Eileen T, O'Toole, Mary, Morphew, Andreas, Hoenger, Peter, Kohl
Publikováno v:
Progress in Biophysics and Molecular Biology
The field of cardiovascular research has benefitted from rapid developments in imaging technology over the last few decades. Accordingly, an ever growing number of large, multidimensional data sets have begun to appear, often challenging existing pre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::6b4674d6b623792ba4e99b6b20cfc541
https://pubmed.ncbi.nlm.nih.gov/27210305
https://pubmed.ncbi.nlm.nih.gov/27210305
Autor:
Callum M. Johnston, June-Chiew Han, Poul M. F. Nielsen, Denis S. Loiselle, Andrew J. Taberner
Publikováno v:
American journal of physiology. Heart and circulatory physiology. 310(11)
The relation between heat output and stress production (force per cross-sectional area) of isolated cardiac tissue is a key metric that provides insight into muscle energetic performance. The heat intercept of the relation, termed “activation heat,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::94b1bb6354f00863307c4a097439a0e4
https://pubmed.ncbi.nlm.nih.gov/27016583
https://pubmed.ncbi.nlm.nih.gov/27016583
Autor:
Callum M. Johnston, Andrew J. Taberner, June-Chiew Han, Denis S. Loiselle, Bryan P. Ruddy, Poul M. F. Nielsen, Toan Pham
Publikováno v:
EMBC
We have developed a new `work-loop calorimeter' that is capable of measuring, simultaneously, the work-done and heat production of isolated cardiac muscle samples at body temperature. Through the innovative use of thermoelectric modules as temperatur
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6643edcdd124f5c8a75686edc7d3b841
https://doi.org/10.1109/embc.2015.7320240
https://doi.org/10.1109/embc.2015.7320240
Publikováno v:
American journal of physiology. Heart and circulatory physiology. 309(2)
Isolated ventricular trabeculae are the most common experimental preparations used in the study of cardiac energetics. However, the experiments have been conducted at subphysiological temperatures. We have overcome this limitation by designing and co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0d0ea9420b967dbf5600615b3ec6f2bb
https://pubmed.ncbi.nlm.nih.gov/26001412
https://pubmed.ncbi.nlm.nih.gov/26001412