Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Callum J McGrenaghan"'
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 15, Iss 6, Pp 1371-1389 (2023)
Backgrounds and Aims: Transfer RNA (tRNA) is the most extensively modified RNA in cells. Queuosine modification is a fundamental process for ensuring the fidelity and efficiency of translation from RNA to protein. In eukaryotes, Queuosine tRNA (Q-tRN
Externí odkaz:
https://doaj.org/article/77df8d28f0ea4e53ba25d622c176dc51
Autor:
Shr-Hau Hung, Gregory I Elliott, Thakku R Ramkumar, Lyubomyr Burtnyak, Callum J McGrenaghan, Sana Alkuzweny, Samia Quaiyum, Dirk Iwata-Reuyl, Xiaobei Pan, Brian D Green, Vincent P Kelly, Valérie de Crécy-Lagard, Manal A Swairjo
Publikováno v:
Hung, S-H, Elliott, G I, Ramkumar, T R, Burtnyak, L, McGrenaghan, C J, Alkuzweny, S, Quaiyum, S, Iwata-Reuyl, D, Pan, X, Green, B D, Kelly, V P, de Crécy-Lagard, V & Swairjo, M A 2023, ' Structural basis of Qng1-mediated salvage of the micronutrient queuine from queuosine-5'-monophosphate as the biological substrate ', Nucleic Acids Research, vol. 51, no. 2, pp. 935–951 . https://doi.org/10.1093/nar/gkac1231
Eukaryotic life benefits from—and ofttimes critically relies upon—the de novo biosynthesis and supply of vitamins and micronutrients from bacteria. The micronutrient queuosine (Q), derived from diet and/or the gut microbiome, is used as a source
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::17c2d2b7a8865610a99c66710185cbb3
https://pubmed.ncbi.nlm.nih.gov/36610787
https://pubmed.ncbi.nlm.nih.gov/36610787
Autor:
Patti Hayes, Claire Fergus, Magda Ghanim, Derek P. Nolan, Vincent P. Kelly, Francesca Tuorto, Callum J. McGrenaghan, Lyubomyr Burtnyak, Cansu Cirzi
Publikováno v:
Nutrients
Volume 12
Issue 3
Nutrients 12 (2020). doi:10.3390/nu12030871
info:cnr-pdr/source/autori:Hayes, Patti; Fergus, Claire; Ghanim, Magda; Cirzi, Cansu; Burtnyak, Lyubomyr; McGrenaghan, Callum J.; Tuorto, Francesca; Nolan, Derek P.; Kelly, Vincent P./titolo:Queuine Micronutrient Deficiency Promotes Warburg Metabolism and Reversal of the Mitochondrial ATP Synthase in Hela Cells/doi:10.3390%2Fnu12030871/rivista:Nutrients/anno:2020/pagina_da:/pagina_a:/intervallo_pagine:/volume:12
Nutrients, Vol 12, Iss 3, p 871 (2020)
Volume 12
Issue 3
Nutrients 12 (2020). doi:10.3390/nu12030871
info:cnr-pdr/source/autori:Hayes, Patti; Fergus, Claire; Ghanim, Magda; Cirzi, Cansu; Burtnyak, Lyubomyr; McGrenaghan, Callum J.; Tuorto, Francesca; Nolan, Derek P.; Kelly, Vincent P./titolo:Queuine Micronutrient Deficiency Promotes Warburg Metabolism and Reversal of the Mitochondrial ATP Synthase in Hela Cells/doi:10.3390%2Fnu12030871/rivista:Nutrients/anno:2020/pagina_da:/pagina_a:/intervallo_pagine:/volume:12
Nutrients, Vol 12, Iss 3, p 871 (2020)
Queuine is a eukaryotic micronutrient, derived exclusively from eubacteria. It is incorporated into both cytosolic and mitochondrial transfer RNA to generate a queuosine nucleotide at position 34 of the anticodon loop. The transfer RNA of primary tum
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0da8913a07ed864457f1e83335de2a38