Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Callum Hicks"'
Publikováno v:
Nutrients, Vol 12, Iss 6, p 1569 (2020)
Background: Binge-eating disorder is a pervasive addiction-like disorder that is defined by excessive and uncontrollable consumption of food within brief periods of time. The aim of the current study was to examine the role of the brain noradrenergic
Externí odkaz:
https://doaj.org/article/9e6cca1700314db0b274510aecfc904a
Autor:
Craig P Motbey, Emily Karanges, Kong M Li, Shane Wilkinson, Adam R Winstock, John Ramsay, Callum Hicks, Michael D Kendig, Naomi Wyatt, Paul D Callaghan, Iain S McGregor
Publikováno v:
PLoS ONE, Vol 7, Iss 9, p e45473 (2012)
Mephedrone (4-methylmethcathinone, MMC) is a popular recreational drug, yet its potential harms are yet to be fully established. The current study examined the impact of single or repeated MMC exposure on various neurochemical and behavioral measures
Externí odkaz:
https://doaj.org/article/64e0f058b7d54634bd898e7984ee7e5d
Autor:
Glenn E. Hunt, Bruno W. Dampney, Linnet Ramos, Iain S. McGregor, Callum Hicks, Sarah J. Baracz
Publikováno v:
Brain Research Bulletin. 127:208-218
Peripherally administered oxytocin induces a wide range of behavioural and physiological effects that are thought to be mediated by the oxytocin receptor (OTR). However, oxytocin also has considerable affinity for the vasopressin 1A receptor (V1AR),
Autor:
Jonna M. Leyrer-Jackson, Callum Hicks, Steven J. Simmons, Chicora F. Oliver, Scott M. Rawls, John W. Muschamp, M. Foster Olive
Cathinone is a plant alkaloid found in khat leaves of perennial shrubs grown in East Africa. Similar to cocaine, cathinone elicits psychostimulant effects which are in part attributed to its amphetamine-like structure. Around 2010, home laboratories
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d5db80ae16edd3e4e3422b7fef3a8f98
https://europepmc.org/articles/PMC6197900/
https://europepmc.org/articles/PMC6197900/
Autor:
Garry R. Smith, Sunil U. Nayak, Peng Huang, Yohanka Caro, Scott M. Rawls, Linnet Ramos, Allen B. Reitz, David Y.W. Lee, Lee-Yuan Liu-Chen, Callum Hicks
Publikováno v:
ACS chemical neuroscience. 9(6)
Psychostimulant reinforcement is mediated by stimulation of both dopamine (DA) D1-like and D2-like receptors, suggesting that pharmacotherapy agents with a dual DA receptor mechanism may be useful for managing psychostimulant abuse. (-)-Stepholidine
Publikováno v:
Addiction Biology. 21:304-315
The neuropeptide oxytocin (OT), given acutely, reduces self-administration of the psychostimulant drug methamphetamine (METH). Additionally, chronic OT administration to adolescent rats reduces levels of alcohol consumption in adulthood, suggesting d
Publikováno v:
Advances in Experimental Medicine and Biology ISBN: 9783319501727
Adv Exp Med Biol
Adv Exp Med Biol
Thanks to advances in neuroscience, addiction is now recognized as a chronic brain disease with genetic, developmental, and cultural components. Drugs of abuse, including alcohol, are able to produce significant neuroplastic changes responsible for t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7cb825f7da2ef8c0b1067b32cdfe0e03
https://doi.org/10.1007/978-3-319-50174-1_13
https://doi.org/10.1007/978-3-319-50174-1_13
Publikováno v:
Psychoneuroendocrinology. 46:46-51
The neuropeptides vasopressin (AVP) and oxytocin (OT) have therapeutic potential across a range of psychiatric disorders. However, there is uncertainty about the effectiveness of the intranasal route of administration that is often used to deliver th
Autor:
Callum Hicks, Rajeshwar Narlawar, G H Misagh, Iain S. McGregor, Tristan A. Reekie, Linnet Ramos, Michael Kassiou
Publikováno v:
British Journal of Pharmacology. 171:2868-2887
Background and Purpose There is current interest in oxytocin (OT) as a possible therapeutic in psychiatric disorders. However, the usefulness of OT may be constrained by peripheral autonomic effects, which may involve an action at both OT and vasopre
Publikováno v:
Drug and alcohol dependence. 178
Background and purpose The neuropharmacological profile of the synthetic cathinone mephedrone (MEPH) is influenced by stereochemistry. Both MEPH enantiomers are monoamine transporter substrates, but R-MEPH is primarily responsible for rewarding effec