Zobrazeno 1 - 10
of 34
pro vyhledávání: '"Calli Latimer"'
Autor:
Patrick S. Tarpey, Sam Behjati, Matthew D. Young, Inigo Martincorena, Ludmil B. Alexandrov, Sarah J. Farndon, Charlotte Guzzo, Claire Hardy, Calli Latimer, Adam P. Butler, Jon W. Teague, Adam Shlien, P. Andrew Futreal, Sohrab Shah, Ali Bashashati, Farzad Jamshidi, Torsten O. Nielsen, David Huntsman, Daniel Baumhoer, Sebastian Brandner, Jay Wunder, Brendan Dickson, Patricia Cogswell, Josh Sommer, Joanna J. Phillips, M. Fernanda Amary, Roberto Tirabosco, Nischalan Pillay, Stephen Yip, Michael R. Stratton, Adrienne M. Flanagan, Peter J. Campbell
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-6 (2017)
Chordoma is a rare often incurable malignant bone tumour. Here, the authors investigate driver mutations of sporadic chordoma in 104 cases, revealing duplications in notochordal transcription factor brachyury (T), PI3K signalling mutations, and mutat
Externí odkaz:
https://doaj.org/article/208559b87d8a4491810952fc9347c3ba
Autor:
Sam Behjati, Patrick S. Tarpey, Kerstin Haase, Hongtao Ye, Matthew D. Young, Ludmil B. Alexandrov, Sarah J. Farndon, Grace Collord, David C. Wedge, Inigo Martincorena, Susanna L. Cooke, Helen Davies, William Mifsud, Mathias Lidgren, Sancha Martin, Calli Latimer, Mark Maddison, Adam P. Butler, Jon W. Teague, Nischalan Pillay, Adam Shlien, Ultan McDermott, P. Andrew Futreal, Daniel Baumhoer, Olga Zaikova, Bodil Bjerkehagen, Ola Myklebost, M. Fernanda Amary, Roberto Tirabosco, Peter Van Loo, Michael R. Stratton, Adrienne M. Flanagan, Peter J. Campbell
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-8 (2017)
Osteosarcoma is a primary malignancy of bone that affects children and adults. Here, the authors sequence childhood and adult osteosarcomas, identifying mutations in insulin-like growth factor signalling genes and distinct genomic rearrangement profi
Externí odkaz:
https://doaj.org/article/4d580842711a47b9a0ba6bb379bd365f
Autor:
Sam Behjati, Gunes Gundem, David C. Wedge, Nicola D. Roberts, Patrick S. Tarpey, Susanna L. Cooke, Peter Van Loo, Ludmil B. Alexandrov, Manasa Ramakrishna, Helen Davies, Serena Nik-Zainal, Claire Hardy, Calli Latimer, Keiran M. Raine, Lucy Stebbings, Andy Menzies, David Jones, Rebecca Shepherd, Adam P. Butler, Jon W. Teague, Mette Jorgensen, Bhavisha Khatri, Nischalan Pillay, Adam Shlien, P. Andrew Futreal, Christophe Badie, ICGC Prostate Group, Ultan McDermott, G. Steven Bova, Andrea L. Richardson, Adrienne M. Flanagan, Michael R. Stratton, Peter J. Campbell
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-8 (2016)
Ionizing radiation may induce irreparable DNA damage leading to cancer. Here, the authors identify a specific signature of mutations arising in patients exposed to ionizing radiation and suggest that radiation-induced tumorigenesis is associated with
Externí odkaz:
https://doaj.org/article/6591661632a94c5d9e36a5a48f8dcf2c
Autor:
S M Ashiqul Islam, Irina I. Abnizova, James McKay, Yudou He, Estelle Chanudet, Behnoush Abedi-Ardekani, Dariush Nasrollahzadeh, Michael Eden, Alisa M. Goldstein, Jon W. Teague, Blandina T. Mmbaga, Nan Hu, Karl Smith-Byrne, Sandra Perdomo, Jingwei Wang, Christine Carreira, Jean-Yves Scoazec, Rebecca C. Fitzgerald, Luis Felipe Ribeiro, Michael R. Stratton, Samad Gharavi, Sergey Senkin, Erik N Bergstrom, Hiva Saffar, Sarah Moody, Sheila Coelho Soares-Lima, Pauline E Bucciarelli, Stefano Serra, Ghislaine Scelo, Charles Dzamalala, Valerie McCormack, Reza Malekzadeh, Hossein Poustchi, Valerie Gaborieau, Lia S Campos, Joshua R. Atkins, Paul Brennan, Emily Thomas, David T. Jones, Paul Richman, Farid Azmoudeh-Ardalan, Masoud Sotoudeh, Ahmadreza Niavarani, Tatsuhiro Shibata, Calli Latimer, Stephen Fitzgerald, Ludmil B Alexandrov, Ricardo Cortez Cardoso Penha, Abdolreza Fazel, Laura Humphreys, Azhar Khandekar, Arash Nikmanesh, Diana Menya
Publikováno v:
Nature Genetics. 53:1553-1563
Esophageal squamous cell carcinoma (ESCC) shows remarkable variation in incidence that is not fully explained by known lifestyle and environmental risk factors. It has been speculated that an unknown exogenous exposure(s) could be responsible. Here w
Autor:
Yichen Wang, Sarah Moody, Behnoush Abedi-Ardekani, Calli Latimer, Saamin Cheema, Jingwei Wang, Stephen Fitzgerald, Laura Humphreys, Paul Brennan, Michael R. Stratton
Publikováno v:
Cancer Research. 83:1168-1168
In recent years, large-scale whole genome sequencing of multiple types of cancer across multiple continents has been conducted as part of the “Mutographs” Cancer Grand Challenge to uncover unknown causes of cancer through detection of signatures
Autor:
Alexandra Colquhoun, Andrew Menzies, Andrew R. J. Lawson, Jose M. C. Tubio, Michael R. Stratton, Luiza Moore, Tim H. H. Coorens, Krishnaa T. Mahbubani, Inigo Martincorena, William Turner, Nicholas Williams, Laura O’Neill, Luke M. R. Harvey, Peter J. Campbell, Jyoti Nangalia, Kourosh Saeb-Parsy, Harald Vöhringer, Bethany Bareham, Sonia Zumalave, Calli Latimer, Vincent Gnanapragasam, Benjamin Thomas, Federico Abascal, Alex Cagan, Mathijs A. Sanders, Anne Y. Warren, Tim Butler, Keiran Raine, Doris Rassl, Yvette Hooks, Moritz Gerstung, Thomas J. Mitchell
Publikováno v:
Science, 370(6512), 75-82. American Association for the Advancement of Science
Genetic profiles of the bladder Depending on the environment of the individual, the human bladder can be exposed to carcinogens as they are flushed through the body. Lawson et al. and Li et al. examined the genetic composition of laser-dissected micr
Autor:
Jean-Yves Scoazec, S M Ashiqul Islam, Irina I. Abnizova, Diana Menya, Paul Richman, Dariush Nasrollahzadeh, Michael R. Stratton, Charles Dzamalala, Sergey Senkin, Karl Smith-Byrne, Hiva Saffar, Pauline E Bucciarelli, Christine Carreira, Sarah Moody, Michael Eden, Paul Brennan, Yudou He, Lia S Campos, Azhar Khandekar, Erik N. Bergstrom, Arash Nikmanesh, Abdolreza Fazel, Ghislaine Scelo, Valerie Gaborieau, Farid Azmoudeh-Ardelan, Calli Latimer, Ricardo Cortez Cardoso Penha, Laura Humphreys, Stefano Serra, Jon W. Teague, Tatsuhiro Shibata, Ludmil B. Alexandrov, Estelle Chanudet, Masoud Sotoudeh, Jingwei Wang, Blandina T. Mmbaga, Valerie McCormack, Reza Malekzadeh, Rebecca C. Fitzgerald, Joshua R. Atkins, David T. Jones, Sandra Perdomo, Emily Thomas, Luis Felipe Ribeiro, Alisa M. Goldstein, Stephen Fitzgerald, Behnoush Abedi-Ardekani, James McKay, Nan Hu
Esophageal squamous cell carcinoma (ESCC) shows a remarkable variation in incidence which is not fully explained by known lifestyle and environmental risk factors. It has been speculated that an unknown exogenous exposure(s) could be responsible. Her
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::60e3994892074c80c817477151c576fa
https://doi.org/10.1101/2021.04.29.21255920
https://doi.org/10.1101/2021.04.29.21255920
Autor:
Inigo Martincorena, Ruben VanBoxtel, Kevin J. Dawson, Anne Y. Warren, Calli Latimer, Andrew Menzies, Peter J. Campbell, Thomas R. W. Oliver, Michael R. Stratton, Matthew D. C. Neville, Luiza Moore, Raheleh Rahbari, Laura O’Neill, Mette Jorgensen, Tim H. H. Coorens, Mabel J Teng, Rebecca C. Fitzgerald, Yvette Hooks, Tim Butler, Alex Cagan, Ayesha Noorani, Rashesh Sanghvi, Christine A. Iacobuzio-Donahue, Daniel Leongamornlert, Rakesh Heer, Mathijs A. Sanders, Thomas J. Mitchell, Peter R. Ellis
During the course of a lifetime normal human cells accumulate mutations. Here, using multiple samples from the same individuals we compared the mutational landscape in 29 anatomical structures from soma and the germline. Two ubiquitous mutational sig
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::db4c6d1f5200964840de84cc28192034
https://doi.org/10.1101/2020.11.25.398172
https://doi.org/10.1101/2020.11.25.398172
Autor:
Thomas R. W. Oliver, Tim H. H. Coorens, Rakesh Heer, Kevin J. Dawson, Mabel J Teng, Daniel Leongamornlert, Ruben van Boxtel, Calli Latimer, Michael R. Stratton, Rashesh Sanghvi, Ayesha Noorani, Raheleh Rahbari, Inigo Martincorena, Laura O’Neill, Thomas J. Mitchell, Mathijs A. Sanders, Mette Jorgensen, Matthew D. C. Neville, Rebecca C. Fitzgerald, Peter R. Ellis, Christine A. Iacobuzio-Donahue, Alex Cagan, Andrew Menzies, Peter J. Campbell, Tim Butler, Yvette Hooks, Luiza Moore, Anne Y. Warren
Publikováno v:
Nature, 597(7876), 381-386. Nature Publishing Group
Over the course of an individual’s lifetime, normal human cells accumulate mutations1. Here we compare the mutational landscape in 29 cell types from the soma and germline using multiple samples from the same individuals. Two ubiquitous mutational
Autor:
Hayley C. Whitaker, Zsofia Kote-Jarai, Matti Annala, Matti Nykter, Douglas F. Easton, Elli Papaemmanuil, Michael R. Emmert-Buck, David C. Wedge, Jose M. C. Tubio, Ultan McDermott, Christopher S. Foster, Sarah O’Meara, William B. Isaacs, Gunes Gundem, Peter J. Campbell, Kevin J. Dawson, David E. Neal, Heini Kallio, Victoria Goody, Tapio Visakorpi, Kati Kivinummi, Gunilla Hägnäs, Rosalind A. Eeles, Peter Van Loo, Barbara Kremeyer, Ludmil B. Alexandrov, G. Steven Bova, Daniel Brewer, Colin Cooper, Calli Latimer
Publikováno v:
ICGC Prostate UK Group* 2020, ' Author Correction : The evolutionary history of lethal metastatic prostate cancer ', Nature, vol. 584, no. 7820, pp. E18 . https://doi.org/10.1038/s41586-020-2581-5
In the Supplementary Information of this Article, some errors were made in compiling the Supplementary Data file called ‘Supplementary Variant Lists’. In the first worksheet (entitled ‘subs’) the clusters to which some single nucleotide varia
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e3e0ee015d14d9264b97ae33ccb33087
https://research.manchester.ac.uk/en/publications/373cdd76-ff88-4133-b6c8-fdc22a6c1e0f
https://research.manchester.ac.uk/en/publications/373cdd76-ff88-4133-b6c8-fdc22a6c1e0f