Zobrazeno 1 - 10
of 39
pro vyhledávání: '"Callen T. Wallace"'
Autor:
Leonardo D’Aiuto, Jill K. Caldwell, Callen T. Wallace, Tristan R. Grams, Maribeth A. Wesesky, Joel A. Wood, Simon C. Watkins, Paul R. Kinchington, David C. Bloom, Vishwajit L. Nimgaonkar
Publikováno v:
Cells, Vol 11, Iss 22, p 3539 (2022)
Intrauterine infections during pregnancy by herpes simplex virus (HSV) can cause significant neurodevelopmental deficits in the unborn/newborn, but clinical studies of pathogenesis are challenging, and while animal models can model some aspects of di
Externí odkaz:
https://doaj.org/article/3e1e0d48f52b43589d053a8362073025
Autor:
Adrian E. Morelli, Tina L. Sumpter, Darling M. Rojas-Canales, Mohna Bandyopadhyay, Zhizhao Chen, Olga Tkacheva, William J. Shufesky, Callen T. Wallace, Simon C. Watkins, Alexandra Berger, Christopher J. Paige, Louis D. Falo, Jr., Adriana T. Larregina
Publikováno v:
Cell Reports, Vol 30, Iss 10, Pp 3448-3465.e8 (2020)
Summary: Efficient Ca2+ flux induced during cognate T cell activation requires signaling the T cell receptor (TCR) and unidentified G-protein-coupled receptors (GPCRs). T cells express the neurokinin-1 receptor (NK1R), a GPCR that mediates Ca2+ flux
Externí odkaz:
https://doaj.org/article/8754f15be35f40a1af5f7a3af7cdad07
Autor:
Brian A. Boone, Pranav Murthy, Jennifer Miller-Ocuin, W. Reed Doerfler, Jarrod T. Ellis, Xiaoyan Liang, Mark A. Ross, Callen T. Wallace, Jason L. Sperry, Michael T. Lotze, Matthew D. Neal, Herbert J. Zeh
Publikováno v:
BMC Cancer, Vol 18, Iss 1, Pp 1-12 (2018)
Abstract Background The hypercoagulable state associated with pancreatic adenocarcinoma (PDA) results in increased risk of venous thromboembolism, leading to substantial morbidity and mortality. Recently, neutrophil extracellular traps (NETs), whereb
Externí odkaz:
https://doaj.org/article/7bb851ee267642998fc7ef74c6f8bd4d
Autor:
Laura Garcia-Exposito, Elodie Bournique, Valérie Bergoglio, Arindam Bose, Jonathan Barroso-Gonzalez, Sufang Zhang, Justin L. Roncaioli, Marietta Lee, Callen T. Wallace, Simon C. Watkins, Patricia L. Opresko, Jean-Sébastien Hoffmann, Roderick J. O’Sullivan
Publikováno v:
Cell Reports, Vol 17, Iss 7, Pp 1858-1871 (2016)
Cancer cells rely on the activation of telomerase or the alternative lengthening of telomeres (ALT) pathways for telomere maintenance and survival. ALT involves homologous recombination (HR)-dependent exchange and/or HR-associated synthesis of telome
Externí odkaz:
https://doaj.org/article/d1fefe0ced02471e9ae73019ba400bad
Autor:
Aliyah M. Weinstein, Lu Chen, Emily A. Brzana, Prashanti R. Patil, Jennifer L. Taylor, Kellsye L. Fabian, Callen T. Wallace, Sabrina D. Jones, Simon C. Watkins, Binfeng Lu, David F. Stroncek, Timothy L. Denning, Yang-Xin Fu, Peter A. Cohen, Walter J. Storkus
Publikováno v:
OncoImmunology, Vol 6, Iss 6 (2017)
We have previously reported that direct injection of dendritic cells (DC) engineered to express the Type-1 transactivator Tbet (i.e., DC.Tbet) into murine tumors results in antitumor efficacy in association with the development of structures resembli
Externí odkaz:
https://doaj.org/article/ae1cf937d236486eb5995d5b55f30a66
Autor:
Steffi Oesterreich, Adrian V. Lee, Jennifer M. Atkinson, Peter C. Lucas, Ben H. Park, Jens-Uwe Blohmer, Maria M. Karsten, Carsten Denkert, Paul Jank, Jason S. Carroll, Nikhil Wagle, George C. Tseng, Li Zhu, Elena Guerini-Rocco, Caterina Fumagalli, Simon C. Watkins, Callen T. Wallace, Prithu Sundd, Maritza A. Montanez, Massimo Cristofanilli, Youbin Zhang, Lorenzo Gerratana, Qiang Zhang, Dorraya El-Ashry, Benjamin Troness, Jennifer K. Richer, Jason Gertz, Spencer Arnesen, Laki Buluwela, Simak Ali, Azadeh Nasrazadani, Nolan M. Priedigkeit, Kevin M. Levine, Jian Chen, Amir Bahreini, Nilgun Tasdemir, Megan E. Yates, Yang Wu, Zheqi Li
Supplementary Data from Hotspot ESR1 Mutations Are Multimodal and Contextual Modulators of Breast Cancer Metastasis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::11b63c7d873493580bae33876033436b
https://doi.org/10.1158/0008-5472.22431151
https://doi.org/10.1158/0008-5472.22431151
Autor:
Steffi Oesterreich, Adrian V. Lee, Jennifer M. Atkinson, Peter C. Lucas, Ben H. Park, Jens-Uwe Blohmer, Maria M. Karsten, Carsten Denkert, Paul Jank, Jason S. Carroll, Nikhil Wagle, George C. Tseng, Li Zhu, Elena Guerini-Rocco, Caterina Fumagalli, Simon C. Watkins, Callen T. Wallace, Prithu Sundd, Maritza A. Montanez, Massimo Cristofanilli, Youbin Zhang, Lorenzo Gerratana, Qiang Zhang, Dorraya El-Ashry, Benjamin Troness, Jennifer K. Richer, Jason Gertz, Spencer Arnesen, Laki Buluwela, Simak Ali, Azadeh Nasrazadani, Nolan M. Priedigkeit, Kevin M. Levine, Jian Chen, Amir Bahreini, Nilgun Tasdemir, Megan E. Yates, Yang Wu, Zheqi Li
Constitutively active estrogen receptor α (ER/ESR1) mutations have been identified in approximately one-third of ER+ metastatic breast cancers. Although these mutations are known as mediators of endocrine resistance, their potential role in promotin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c2f3cbfdf669ffc0225f181ab59c07b4
https://doi.org/10.1158/0008-5472.c.6513817
https://doi.org/10.1158/0008-5472.c.6513817
Autor:
Urvi Gupta, Sayan Ghosh, Callen T. Wallace, Peng Shang, Ying Xin, Archana Padmanabhan Nair, Meysam Yazdankhah, Anastasia Strizhakova, Mark A. Ross, Haitao Liu, Stacey Hose, Nadezda A. Stepicheva, Olivia Chowdhury, Mihir Nemani, Vishnu Maddipatla, Rhonda Grebe, Manjula Das, Kira L. Lathrop, José-Alain Sahel, J. Samuel Zigler, Jiang Qian, Arkasubhra Ghosh, Yuri Sergeev, James T. Handa, Claudette M. St. Croix, Debasish Sinha
Publikováno v:
Autophagy
In dry age-related macular degeneration (AMD), LCN2 (lipocalin 2) is upregulated. Whereas LCN2 has been implicated in AMD pathogenesis, the mechanism remains unknown. Here, we report that in retinal pigmented epithelial (RPE) cells, LCN2 regulates ma
Autor:
Zheqi Li, Yang Wu, Megan E. Yates, Nilgun Tasdemir, Amir Bahreini, Jian Chen, Kevin M. Levine, Nolan M. Priedigkeit, Azadeh Nasrazadani, Simak Ali, Laki Buluwela, Spencer Arnesen, Jason Gertz, Jennifer K. Richer, Benjamin Troness, Dorraya El-Ashry, Qiang Zhang, Lorenzo Gerratana, Youbin Zhang, Massimo Cristofanilli, Maritza A. Montanez, Prithu Sundd, Callen T. Wallace, Simon C. Watkins, Caterina Fumagalli, Elena Guerini-Rocco, Li Zhu, George C. Tseng, Nikhil Wagle, Jason S. Carroll, Paul Jank, Carsten Denkert, Maria M. Karsten, Jens-Uwe Blohmer, Ben H. Park, Peter C. Lucas, Jennifer M. Atkinson, Adrian V. Lee, Steffi Oesterreich
Publikováno v:
Cancer Res
Constitutively active estrogen receptor α (ER/ESR1) mutations have been identified in approximately one-third of ER+ metastatic breast cancers. Although these mutations are known as mediators of endocrine resistance, their potential role in promotin
Autor:
Simon C. Watkins, Cheryl A. Telmer, Jinwoo Ahn, Zhou Zhong, Jiying Ning, Zandrea Ambrose, Alan Engelman, Marcel P. Bruchez, Sooin Jang, Emerson A. Boggs, Callen T. Wallace, Peijun Zhang
Publikováno v:
mBio
mBio, Vol 12, Iss 2 (2021)
mBio, Vol 12, Iss 2 (2021)
HIV is the causative agent of AIDS, which has no cure. The protein shell that encases the viral genome, the capsid, is critical for HIV replication in cells at multiple steps.
Human immunodeficiency virus type 1 (HIV-1) capsid binds host protein
Human immunodeficiency virus type 1 (HIV-1) capsid binds host protein
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ea2ee0b80b1ffc3d200d4e467810e8f1
https://ora.ox.ac.uk/objects/uuid:2faa0406-9d36-4946-9b20-7a605032f2d1
https://ora.ox.ac.uk/objects/uuid:2faa0406-9d36-4946-9b20-7a605032f2d1