Diagnosis of childhood febrile illness using a multi-class blood RNA molecular signature.

Autor: Habgood-Coote D; Section of Paediatric Infectious Disease and Centre for Paediatrics & Child Health, Department of Infectious Disease, Imperial College London, London, UK., Wilson C; Section of Paediatric Infectious Disease and Centre for Paediatrics & Child Health, Department of Infectious Disease, Imperial College London, London, UK., Shimizu C; Department of Pediatrics, Rady Children's Hospital San Diego/University of California San Diego School of Medicine, La Jolla, CA, USA., Barendregt AM; Department of Pediatric Immunology, Rheumatology and Infectious Diseases, Emma Children's Hospital, Amsterdam University Medical Center (AUMC), University of Amsterdam, Amsterdam, the Netherlands., Philipsen R; Radboud Institute for Molecular Life Sciences, Radboud University Medical Center, Department of Laboratory Medicine, Nijmegen, the Netherlands., Galassini R; Section of Paediatric Infectious Disease and Centre for Paediatrics & Child Health, Department of Infectious Disease, Imperial College London, London, UK., Calle IR; Pediatrics Department, Translational Pediatrics and Infectious Diseases Section, Santiago de Compostela, Spain; Genetics- Vaccines- Infectious Diseases and Pediatrics Research Group GENVIP, Instituto de Investigación Sanitaria de Santiago (IDIS), Santiago de Compostela, Spain., Workman L; Department of Paediatrics & Child Health, Red Cross Childrens Hospital and SA-MRC Unit on Child & Adolescent Health, University of Cape Town, Cape Town, South Africa., Agyeman PKA; Department of Pediatrics, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland., Ferwerda G; Radboud Institute for Molecular Life Sciences, Radboud University Medical Center, Department of Laboratory Medicine, Nijmegen, the Netherlands., Anderson ST; Medical Research Council Unit, Fajara, The Gambia at the London School of Hygiene and Tropical Medicine, MRCG at LSHTM Fajara, Banjul, The Gambia., van den Berg JM; Department of Pediatric Immunology, Rheumatology and Infectious Diseases, Emma Children's Hospital, Amsterdam University Medical Center (AUMC), University of Amsterdam, Amsterdam, the Netherlands., Emonts M; Great North Children's Hospital, Department of Paediatric Immunology, Infectious Diseases & Allergy and NIHR Newcastle Biomedical Research Centre, Newcastle Upon Tyne Hospitals NHS Foundation Trust, Newcastle Upon Tyne, UK; Translational and Clinical Research Institute, Newcastle University, Newcastle Upon Tyne, UK., Carrol ED; Department of Clinical Infection, Microbiology and Immunology, University of Liverpool Institute of Infection, Veterinary and Ecological Sciences, Liverpool, UK., Fink CG; Micropathology Ltd Research and Diagnosis, Coventry, UK; University of Warwick, Coventry, UK., de Groot R; Radboud Institute for Molecular Life Sciences, Radboud University Medical Center, Department of Laboratory Medicine, Nijmegen, the Netherlands., Hibberd ML; Department of Infection Biology, Faculty of Infectious and Tropical Disease, London School of Hygiene and Tropical Medicine, London, UK., Kanegaye J; Department of Pediatrics, Rady Children's Hospital San Diego/University of California San Diego School of Medicine, La Jolla, CA, USA., Nicol MP; Marshall Centre, School of Biomedical Sciences, University of Western Australia, Perth, Australia., Paulus S; Department of Clinical Infection, Microbiology and Immunology, University of Liverpool Institute of Infection, Veterinary and Ecological Sciences, Liverpool, UK; Oxford Vaccine Group, Department of Paediatrics, University of Oxford and the NIHR Oxford Biomedical Research Centre, Oxford, UK., Pollard AJ; Oxford Vaccine Group, Department of Paediatrics, University of Oxford and the NIHR Oxford Biomedical Research Centre, Oxford, UK., Salas A; Pediatrics Department, Translational Pediatrics and Infectious Diseases Section, Santiago de Compostela, Spain; Genetics- Vaccines- Infectious Diseases and Pediatrics Research Group GENVIP, Instituto de Investigación Sanitaria de Santiago (IDIS), Santiago de Compostela, Spain; Unidade de Xenética, Instituto de Ciencias Forenses (INCIFOR), Facultade de Medicina, Universidade de Santiago de Compostela, and GenPoB Research Group, Instituto de Investigación Sanitaria (IDIS), Hospital Clínico Universitario de Santiago (SERGAS), 15706 Galicia, Spain., Secka F; Medical Research Council Unit, Fajara, The Gambia at the London School of Hygiene and Tropical Medicine, MRCG at LSHTM Fajara, Banjul, The Gambia., Schlapbach LJ; Pediatric and Neonatal Intensive Care Unit, and Children`s Research Center, University Children's Hospital Zurich, Zurich, Switzerland; Child Health Research Centre, The University of Queensland, and Paediatric Intensive Care Unit, Queensland Children's Hospital, Brisbane, QLD, Australia., Tremoulet AH; Department of Pediatrics, Rady Children's Hospital San Diego/University of California San Diego School of Medicine, La Jolla, CA, USA., Walther M; Medical Research Council Unit, Fajara, The Gambia at the London School of Hygiene and Tropical Medicine, MRCG at LSHTM Fajara, Banjul, The Gambia., Zenz W; University Clinic of Paediatrics and Adolescent Medicine, Department of General Paediatrics, Medical University of Graz, Graz, Austria., Van der Flier M; Paediatric Infectious Diseases and Immunology, Wilhelmina Children's Hospital, University Medical Center Utrecht, Utrecht, the Netherlands; Paediatric Infectious Diseases and Immunology Amalia Children's Hospital, Radboudumc, Nijmegen, the Netherlands., Zar HJ; Department of Paediatrics & Child Health, Red Cross Childrens Hospital and SA-MRC Unit on Child & Adolescent Health, University of Cape Town, Cape Town, South Africa., Kuijpers T; Department of Pediatric Immunology, Rheumatology and Infectious Diseases, Emma Children's Hospital, Amsterdam University Medical Center (AUMC), University of Amsterdam, Amsterdam, the Netherlands; Department of Blood Cell Research, Sanquin Blood Supply, Division Research and Landsteiner Laboratory of Amsterdam UMC (AUMC), University of Amsterdam, Amsterdam, the Netherlands., Burns JC; Department of Pediatrics, Rady Children's Hospital San Diego/University of California San Diego School of Medicine, La Jolla, CA, USA., Martinón-Torres F; Pediatrics Department, Translational Pediatrics and Infectious Diseases Section, Santiago de Compostela, Spain; Genetics- Vaccines- Infectious Diseases and Pediatrics Research Group GENVIP, Instituto de Investigación Sanitaria de Santiago (IDIS), Santiago de Compostela, Spain., Wright VJ; Section of Paediatric Infectious Disease and Centre for Paediatrics & Child Health, Department of Infectious Disease, Imperial College London, London, UK., Coin LJM; Department of Microbiology and Immunology, University of Melbourne at The Peter Doherty Institute for Infection and Immunity, Melbourne, VIC, Australia., Cunnington AJ; Section of Paediatric Infectious Disease and Centre for Paediatrics & Child Health, Department of Infectious Disease, Imperial College London, London, UK., Herberg JA; Section of Paediatric Infectious Disease and Centre for Paediatrics & Child Health, Department of Infectious Disease, Imperial College London, London, UK., Levin M; Section of Paediatric Infectious Disease and Centre for Paediatrics & Child Health, Department of Infectious Disease, Imperial College London, London, UK., Kaforou M; Section of Paediatric Infectious Disease and Centre for Paediatrics & Child Health, Department of Infectious Disease, Imperial College London, London, UK. Electronic address: m.kaforou@imperial.ac.uk.

Publikováno v: Med (New York, N.Y.) [Med] 2023 Sep 08; Vol. 4 (9), pp. 635-654.e5. Date of Electronic Publication: 2023 Aug 18.

A NICE combination for predicting hospitalisation at the Emergency Department: a European multicentre observational study of febrile children.

Autor: Borensztajn DM; Erasmus MC Sophia Children's Hospital, Department of General Paediatrics, P.O. Box 2060, 3000 CB, Rotterdam, the Netherlands., Hagedoorn NN; Erasmus MC Sophia Children's Hospital, Department of General Paediatrics, P.O. Box 2060, 3000 CB, Rotterdam, the Netherlands., Carrol ED; University of Liverpool, Institute of Infection and Global Health, Liverpool, United Kingdom.; Alder Hey Children's NHS Foundation Trust, Liverpool, United Kingdom.; Liverpool Health Partners, First Floor, Science Park, Mount Pleasant, Liverpool L3 5TF., von Both U; Division of Paediatric Infectious Diseases, Dr. von Hauner Children's Hospital, university hospital, Ludwig, Ludwig-Maximilians-Universität (LMU), München, Germany., Dewez JE; London School of Hygiene and Tropical Medicine, Faculty of Tropical and Infectious Disease, London, United Kingdom., Emonts M; Great North Children's Hospital, Paediatric Immunology, Infectious Diseases & Allergy, Newcastle upon Tyne Hospitals NHS Foundation Trust, Newcastle upon Tyne, United Kingdom.; Population Health Sciences Institute, Newcastle University, Newcastle upon Tyne, UK.; NIHR Newcastle Biomedical Research Centre based at Newcastle upon Tyne Hospitals NHS Trust and Newcastle University, Westgate Rd, Newcastle upon Tyne NE4 5PL, United Kingdom.; Translational and Clinical Research Institute, Newcastle upon Tyne, United Kingdom., van der Flier M; Paediatric Infectious Diseases and Immunology, Wilhelmina Children's Hospital, University Medical Centre Utrecht, Utrecht, the Netherlands.; Paediatric Infectious Diseases and Immunology, Amalia Children's Hospital, Radboud University Medical Centre, Nijmegen, the Netherlands.; Section Paediatric Infectious Diseases, Laboratory of Medical Immunology, Department of Laboratory Medicine, Radboud Institute for Molecular Sciences, Radboud University Medical Centre, Nijmegen, the Netherlands., de Groot R; Stichting Katholieke Universiteit, Radboudumc Nijmegen, The Netherlands., Herberg J; Imperial College of Science, Technology and Medicine, Section of Paediatric Infectious Diseases, Department of Infectious Diseases, Faculty of Medicine, London, United Kingdom.; Department of paediatric Accident and Emergency, St Mary's hospital - Imperial College NHS Healthcare Trust., Kohlmaier B; Medical University of Graz, Department of General Paediatrics, Graz, Austria., Lim E; Great North Children's Hospital, Paediatric Immunology, Infectious Diseases & Allergy, Newcastle upon Tyne Hospitals NHS Foundation Trust, Newcastle upon Tyne, United Kingdom.; Population Health Sciences Institute, Newcastle University, Newcastle upon Tyne, UK., Maconochie IK; Imperial College of Science, Technology and Medicine, Section of Paediatric Infectious Diseases, Department of Infectious Diseases, Faculty of Medicine, London, United Kingdom.; Department of paediatric Accident and Emergency, St Mary's hospital - Imperial College NHS Healthcare Trust., Martinon-Torres F; Hospital Clínico Universitario de Santiago de Compostela, Genetics, Vaccines, Infections and Paediatrics Research group (GENVIP), Santiago de Compostela, Spain., Nieboer D; Department of Public Health, Erasmus University Medical Centre Rotterdam, The Netherlands., Nijman RG; Imperial College of Science, Technology and Medicine, Section of Paediatric Infectious Diseases, Department of Infectious Diseases, Faculty of Medicine, London, United Kingdom.; Department of paediatric Accident and Emergency, St Mary's hospital - Imperial College NHS Healthcare Trust., Oostenbrink R; Erasmus MC Sophia Children's Hospital, Department of General Paediatrics, P.O. Box 2060, 3000 CB, Rotterdam, the Netherlands., Pokorn M; University Medical Centre Ljubljana, Univerzitetni Klinični Centre, Department of Infectious Diseases, Ljubljana, Slovenia., Calle IR; Hospital Clínico Universitario de Santiago de Compostela, Genetics, Vaccines, Infections and Paediatrics Research group (GENVIP), Santiago de Compostela, Spain., Strle F; University Medical Centre Ljubljana, Univerzitetni Klinični Centre, Department of Infectious Diseases, Ljubljana, Slovenia., Tsolia M; National and Kapodistrian University of Athens, Second Department of Paediatrics, P. and A. Kyriakou Children's Hospital, Athens, Greece., Vermont CL; Erasmus MC Sophia Children's Hospital, Department of Paediatric infectious diseases & immunology, Rotterdam, the Netherlands., Yeung S; London School of Hygiene and Tropical Medicine, Faculty of Tropical and Infectious Disease, London, United Kingdom., Zavadska D; Rīgas Stradiņa Universitāte, Department of Paediatrics; Children clinical university hospital, Riga, Latvia., Zenz W; Medical University of Graz, Department of General Paediatrics, Graz, Austria., Levin M; Imperial College of Science, Technology and Medicine, Section of Paediatric Infectious Diseases, Department of Infectious Diseases, Faculty of Medicine, London, United Kingdom., Moll HA; Erasmus MC Sophia Children's Hospital, Department of General Paediatrics, P.O. Box 2060, 3000 CB, Rotterdam, the Netherlands.

Publikováno v: The Lancet regional health. Europe [Lancet Reg Health Eur] 2021 Jul 12; Vol. 8, pp. 100173. Date of Electronic Publication: 2021 Jul 12 (Print Publication: 2021).