BMP receptor inhibition enhances tissue repair in endoglin heterozygous mice

Autor: Anke M. Smits, Alwin de Jong, Margreet R. de Vries, Marie-José Goumans, Kondababu Kurakula, Kirsten Lodder, Paul H.A. Quax, Hans-Jurgen J. Mager, Karien C. Wiesmeijer, Calinda K. E. Dingenouts, Wineke Bakker

Publikováno v: International Journal of Molecular Sciences, 22(4):2010, 1-19. Multidisciplinary Digital Publishing Institute (MDPI)
International Journal of Molecular Sciences
Volume 22
Issue 4
International Journal of Molecular Sciences, 22(4). MDPI
Bakker, W, Dingenouts, C K E, Lodder, K, Wiesmeijer, K C, de Jong, A, Kurakula, K, Mager, H J J, Smits, A M, de Vries, M R, Quax, P H A & Goumans, M J T H 2021, ' Bmp receptor inhibition enhances tissue repair in endoglin heterozygous mice ', International Journal of Molecular Sciences, vol. 22, no. 4, 2010, pp. 1-19 . https://doi.org/10.3390/ijms22042010
International Journal of Molecular Sciences, Vol 22, Iss 2010, p 2010 (2021)

Hereditary hemorrhagic telangiectasia type 1 (HHT1) is a severe vascular disorder caused by mutations in the TGFβ/BMP co-receptor endoglin. Endoglin haploinsufficiency results in vascular malformations and impaired neoangiogenesis. Furthermore, HHT1

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e6553fd9c02efe074d4d70e8093091f4
https://hdl.handle.net/1887/3214289

Glycosylated Cell Surface Markers for the Isolation of Human Cardiac Progenitors

Autor: Thijs Berends, Asja T. Moerkamp, Noortje A.M. Bax, Calinda K. E. Dingenouts, Marie-José Goumans, Anke M. Smits, Kirsten Lodder, Hau Wan Leung, Stephanie Holst, Andre Choo

Publikováno v: Stem Cells and Development, 26(21), 1552-1565. Mary Ann Liebert Inc.
Stem Cells and Development

The aim of stem cell therapy after cardiac injury is to replace damaged cardiac tissue. Human cardiac progenitor cells (CPCs) represent an interesting cell population for clinical strategies to treat cardiac disease and human CPC-specific antibodies

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::291b69a60962c1bf8a771e752a587261
https://hdl.handle.net/1887/94813

Human fetal and adult epicardial-derived cells: a novel model to study their activation

Autor: Asja T. Moerkamp, Thomas J van Brakel, Calinda K. E. Dingenouts, Marie-José Goumans, Esther Dronkers, Kirsten Lodder, Tessa van Herwaarden, Fredrik C. Tengström, Anke M. Smits

Publikováno v: Stem Cell Research & Therapy
Stem Cell Research and Therapy, 7

Background The epicardium, a cell layer covering the heart, plays an important role during cardiogenesis providing cardiovascular cell types and instructive signals, but becomes quiescent during adulthood. Upon cardiac injury the epicardium is activa

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::84cee67e61fcc1321503ef483a1b8be2
https://doi.org/10.1186/s13287-016-0434-9

Macrophages: New Frontier in Cardiovascular Medicine464STAT4 deficiency exacerbates atherosclerosis by promoting mobilization of myeloid cells, polarization of M1 macrophages and formation of foam cells465Effects of DPP4 inhibition on cardiac regeneration and macrophage balance in a mouse model of HHT-1466Myeloid cell regulation by CD200 signalling in atherosclerosis

Autor: J Yang, Patricia Green, D Danso-Abeam, Junbo Ge, X Yang, S Ding, L Xu, Claudia Monaco, M.J. Goumans, Calinda K. E. Dingenouts, Kirsten Lodder, Wineke Bakker, Michael E. Goddard, Christina Kassiteridi, Jennifer Cole, Inhye Park

Publikováno v: Cardiovascular Research. 111:S83-S83

464 STAT4 deficiency exacerbates atherosclerosis by promoting mobilization of myeloid cells, polarization of M1 macrophages and formation of foam cells {#article-title-2} Background: Atherosclerosis (AS) is a chronic inflammatory disease of large and

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::d3a74004ea7ed2fb0e03c4396083d650
https://doi.org/10.1093/cvr/cvw144