Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Calin Plesa"'
Publikováno v:
Nucleic Acids Research
Nucleic acids research, vol 48, iss 16
Nucleic acids research, vol 48, iss 16
Multiplexed assays allow functional testing of large synthetic libraries of genetic elements, but are limited by the designability, length, fidelity and scale of the input DNA. Here, we improve DropSynth, a low-cost, multiplexed method that builds ge
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::43c8ee80c6be7a10698e401ef223f823
https://doi.org/10.1101/740977
https://doi.org/10.1101/740977
Publikováno v:
Physics Today. 68:40-46
A 70-year-old idea for measuring blood cells has evolved into a powerful, versatile tool for studying DNA, proteins, and other biomolecules.
Publikováno v:
Nano Letters. 15:3153-3158
DNA in cells is heavily covered with all types of proteins that regulate its genetic activity. Detection of DNA-bound proteins is a challenge that is well suited to solid-state nanopores as they provide a linear readout of the DNA and DNA-protein vol
Publikováno v:
Nano Letters. 15:732-737
While understanding translocation of DNA through a solid-state nanopore is vital for exploiting its potential for sensing and sequencing at the single-molecule level, surprisingly little is known about the dynamics of the propagation of DNA through t
Next-generation sequencing has engendered an expanding suite of functional assays that can test sequence-function relationships at unprecedented scales in pooled formats (multiplex). Such assays are currently constrained by the short length of oligon
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::61bacf7ecd45bf4e02b46669dc12c41b
https://doi.org/10.1101/163550
https://doi.org/10.1101/163550
Publikováno v:
2017 10th International Symposium on Advanced Topics in Electrical Engineering (ATEE).
This paper presents an original multithreaded corona electrode, OSIM patented, for the endowment of the electroseparators with rotating cylinder. By construction, the new type of electrode ensures an extension of the intense electric field on an adju
Autor:
Calin Plesa, Stefan W. Kowalczyk, R. Zinsmeester, Yitzhak Rabin, Alexander Y. Grosberg, Cees Dekker
Publikováno v:
Nano Letters. 13:658-663
Measurements on protein translocation through solid-state nanopores reveal anomalous (non-Smoluchowski) transport behavior, as evidenced by extremely low detected event rates, i.e., the capture rates are orders of magnitude smaller than what is theor
Autor:
Cees Dekker, Sergii Pud, Justus W. Ruitenberg, Jaco van der Torre, Magnus P. Jonsson, Menno J. Witteveen, Alexander Y. Grosberg, Daniel Verschueren, Yitzhak Rabin, Calin Plesa
Publikováno v:
Nature Nanotechnology, 11(12)
Nature Nanotechnology
Nature Nanotechnology
Long DNA molecules can self-entangle into knots. Experimental techniques for observing such DNA knots (primarily gel electrophoresis) are limited to bulk methods and circular molecules below 10 kilobase pairs in length. Here, we show that solid-state
Publikováno v:
ACS Nano
We demonstrate the stepwise assembly of a fully addressable polycyclic DNA hexagon nanonetwork for the preparation of a four-ring system, one of the biggest networks yet constructed from tripodal building blocks. We find that the yield exhibits a dis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8b95ff4a4a975ee4cca6f91493708246
https://doi.org/10.1021/nn202568q
https://doi.org/10.1021/nn202568q
Publikováno v:
Nanoscale, 2015,7, 13605-13609
Nanopore experiments have traditionally been carried out with chloride-based solutions. Here we introduce silver/silver-glutamate-based electrochemistry as an alternative, and study the viscosity, conductivity, and nanopore translocation characterist
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f9e6c1b682a3b313627e638d0493cd98
http://resolver.tudelft.nl/uuid:83a50284-3ab2-4cb5-b0d1-620daf35f682
http://resolver.tudelft.nl/uuid:83a50284-3ab2-4cb5-b0d1-620daf35f682