A redox-dependent thiol-switch and a Ca2+ binding site within the hinge region hierarchically depend on each other in α7β1 integrin regulation

Autor: Caliandro, Michele F., Schmalbein, Felix, Todesca, Luca Matteo, Mörgelin, Matthias, Rezaei, Maryam, Meißner, Juliane, Siepe, Isabel, Grosche, Julius, Schwab, Albrecht, Eble, Johannes A.

Publikováno v: In Free Radical Biology and Medicine July 2022 187:38-49

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Extracellular Redox Regulation of α7β Integrin-Mediated Cell Migration Is Signaled via a Dominant Thiol-Switch.

Autor: Bergerhausen, Lukas, Grosche, Julius, Meißner, Juliane, Hecker, Christina, Caliandro, Michele F., Westerhausen, Christoph, Kamenac, Andrej, Rezaei, Maryam, Mörgelin, Matthias, Poschmann, Gereon, Vestweber, Dietmar, Hanschmann, Eva-Maria, Eble, Johannes A.

Publikováno v: Antioxidants; Mar2020, Vol. 9 Issue 3, p227, 1p

The Interaction between Laminin-332 and α3β1 Integrin Determines Differentiation and Maintenance of CAFs, and Supports Invasion of Pancreatic Duct Adenocarcinoma Cells.

Autor: Cavaco ACM; Institute of Physiological Chemistry and Pathobiochemistry, University of Münster, Waldeyerstr. 15, 48149 Münster, Germany. acmcavaco@gmail.com., Rezaei M; Institute of Physiological Chemistry and Pathobiochemistry, University of Münster, Waldeyerstr. 15, 48149 Münster, Germany. mrezaei@uni-muenster.de., Caliandro MF; Institute of Physiological Chemistry and Pathobiochemistry, University of Münster, Waldeyerstr. 15, 48149 Münster, Germany. michele.caliandro@stud.unifi.it., Lima AM; Institute of Physiological Chemistry and Pathobiochemistry, University of Münster, Waldeyerstr. 15, 48149 Münster, Germany. augustomlima@gmail.com., Stehling M; Department of Cell and Developmental Biology, Max Planck Institute for Molecular Biomedicine, Röntgenstraße 20, 48149 Münster, Germany. martin.stehling@mpi-muenster.mpg.de., Dhayat SA; Department of General,Visceral and Transplantation Surgery, University Hospital Münster, Albert-Schweitzer-Campus 1 (W1), , 48149 Münster, Germany. sameer.dhayat@ukmuenster.de., Haier J; Department of General,Visceral and Transplantation Surgery, University Hospital Münster, Albert-Schweitzer-Campus 1 (W1), , 48149 Münster, Germany. joerg.haier@nordakademie.de., Brakebusch C; Biotech Research and Innovation Center (BRIC), University of Copenhagen, Ole Maaløes vej 5, 2200 Copenhagen, Denmark. cordbrakebusch@gmail.com., Eble JA; Institute of Physiological Chemistry and Pathobiochemistry, University of Münster, Waldeyerstr. 15, 48149 Münster, Germany. johannes.eble@uni-muenster.de.

Publikováno v: Cancers [Cancers (Basel)] 2018 Dec 21; Vol. 11 (1). Date of Electronic Publication: 2018 Dec 21.