Zobrazeno 1 - 10
of 311
pro vyhledávání: '"Calfee CS"'
Autor:
Sinha, P, Calfee, CS, Cherian, S, Brealey, D, Cutler, S, King, C, Killick, C, Richards, O, Cheema, Y, Bailey, C, Reddy, K, Delucchi, KL, Gordon, A, Shankar-Hari, M, Shyamsundar, M, O'Kane, CM, McAuley, DF, Szakmany, T
Rationale: In non-COVID-19 ARDS, two phenotypes, based on the severity of systemic inflammation, have been described. The hyperinflammatory phenotype is known to be associated with increased multi-organ failure and mortality. In this study, we aimed
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od______1032::2848dcdea03cfead45ed3a1b5d041a41
http://hdl.handle.net/10044/1/81051
http://hdl.handle.net/10044/1/81051
Autor:
Liu, Kathleen, Bhatraju, PK, Mukherjee, P, Robinson-Cohen, C, O'Keefe, GE, Frank, AJ, Christie, JD, Meyer, NJ, Liu, KD, Matthay, MA, Calfee, CS
Publikováno v:
Liu, Kathleen; Bhatraju, PK; Mukherjee, P; Robinson-Cohen, C; O'Keefe, GE; Frank, AJ; et al.(2016). Acute kidney injury subphenotypes based on creatinine trajectory identifies patients at increased risk of death. UC San Francisco: Retrieved from: http://www.escholarship.org/uc/item/1032s6p6
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od_______325::4c35ab2d758dc2384b678de8e898f17f
http://www.escholarship.org/uc/item/1032s6p6
http://www.escholarship.org/uc/item/1032s6p6
Autor:
Matthay, Michael, Orwoll, BE, Spicer, AC, Zinter, MS, Alkhouli, MF, Khemani, RG, Flori, HR, Neuhaus, JM, Calfee, CS, Matthay, MA, Sapru, A
Publikováno v:
Matthay, Michael; Orwoll, BE; Spicer, AC; Zinter, MS; Alkhouli, MF; Khemani, RG; et al.(2015). Elevated soluble thrombomodulin is associated with organ failure and mortality in children with acute respiratory distress syndrome (ARDS): A prospective observational cohort study. UC San Francisco: Retrieved from: http://www.escholarship.org/uc/item/6vc1x0gs
© 2015 Orwoll et al.Introduction: The significance of endothelial injury in children with the acute respiratory distress syndrome (ARDS) has not been well studied. Plasma levels of soluble thrombomodulin (sTM), an endothelial surface protein involve
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od_______325::f4d2ee5ecec694a82ed7ffafe79f413e
http://www.escholarship.org/uc/item/6vc1x0gs
http://www.escholarship.org/uc/item/6vc1x0gs
Autor:
Sapru, A, Calfee, CS, Liu, KD, Kangelaris, K, Hansen, H, Pawlikowska, L, Ware, LB, Alkhouli, MF, Abbott, J, Matthay, MA
Publikováno v:
Intensive Care Medicine, vol 41, iss 3
Sapru, A; Calfee, CS; Liu, KD; Kangelaris, K; Hansen, H; Pawlikowska, L; et al.(2015). Erratum to: Plasma soluble thrombomodulin levels are associated with mortality in the acute respiratory distress syndrome [Intensive Care Med, 10.1007/s00134-015-3648-x]. Intensive Care Medicine, 41(3), 574. doi: 10.1007/s00134-015-3703-7. UC San Francisco: Retrieved from: http://www.escholarship.org/uc/item/64c2j6m3
Sapru, A; Calfee, CS; Liu, KD; Kangelaris, K; Hansen, H; Pawlikowska, L; et al.(2015). Erratum to: Plasma soluble thrombomodulin levels are associated with mortality in the acute respiratory distress syndrome [Intensive Care Med, 10.1007/s00134-015-3648-x]. Intensive Care Medicine, 41(3), 574. doi: 10.1007/s00134-015-3703-7. UC San Francisco: Retrieved from: http://www.escholarship.org/uc/item/64c2j6m3
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::05da8665e57f8cf8b3791fc7d7de8f4c
https://escholarship.org/uc/item/64c2j6m3
https://escholarship.org/uc/item/64c2j6m3
Autor:
Sapru, A, Calfee, CS, Liu, KD, Kangelaris, K, Hansen, H, Pawlikowska, L, Ware, LB, Alkhouli, MF, Abbot, J, Matthay, MA, The, NAN
Publikováno v:
Intensive care medicine, vol 41, iss 3
Sapru, A; Calfee, CS; Liu, KD; Kangelaris, K; Hansen, H; Pawlikowska, L; et al.(2015). Plasma soluble thrombomodulin levels are associated with mortality in the acute respiratory distress syndrome. Intensive Care Medicine. doi: 10.1007/s00134-015-3648-x. UC San Francisco: Retrieved from: http://www.escholarship.org/uc/item/7bq8q4qk
Sapru, A; Calfee, CS; Liu, KD; Kangelaris, K; Hansen, H; Pawlikowska, L; et al.(2015). Plasma soluble thrombomodulin levels are associated with mortality in the acute respiratory distress syndrome. Intensive Care Medicine. doi: 10.1007/s00134-015-3648-x. UC San Francisco: Retrieved from: http://www.escholarship.org/uc/item/7bq8q4qk
ObjectiveThombomodulin (TM) is an activator of protein C and a biomarker for endothelial injury. We hypothesized that (1) elevated plasma levels would be associated with clinical outcomes and (2) polymorphisms in the TM gene would be associated with
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::3097819ebcebeaee832eaa907f2f1cf4
https://escholarship.org/uc/item/7bq8q4qk
https://escholarship.org/uc/item/7bq8q4qk
Publikováno v:
Chest, vol 147, iss 6
Background:The Acute Respiratory Distress Syndrome (ARDS) is a heterogeneous syndrome that encompasses lung injury from both direct and indirect sources. Direct ARDS (pneumonia, aspiration) has been hypothesized to cause more severe lung epithelial i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od_______325::15b0ce1d42a2242a0b1dd8ad2e94a562
https://escholarship.org/uc/item/7cs5q0br
https://escholarship.org/uc/item/7cs5q0br
Autor:
Ware, LB, Lee, JW, Wickersham, N, Nguyen, J, Matthay, MA, Calfee, CS, California Transplant Donor Network
Publikováno v:
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons, vol 14, iss 10
Although recipients of donor lungs from smokers have worse clinical outcomes, the underlying mechanisms are unknown. We tested the association between donor smoking and the degree of pulmonary edema (as estimated by lung weight), the rate of alveolar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od_______325::be1796d69f8ee20d73cc5f874bac71c7
https://escholarship.org/uc/item/9k59v37p
https://escholarship.org/uc/item/9k59v37p
Autor:
Matthay, Michael, Calfee, Carolyn, Kangelaris, KN, Calfee, CS, May, AK, Zhuo, H, Matthay, MA, Ware, LB
Publikováno v:
Matthay, Michael; Calfee, Carolyn; Kangelaris, KN; Calfee, CS; May, AK; Zhuo, H; et al.(2014). Is there still a role for the lung injury score in the era of the Berlin definition ARDS?. UC San Francisco: Retrieved from: http://www.escholarship.org/uc/item/2763j360
Background: The Lung Injury Score (LIS) remains a commonly utilized measure of lung injury severity though the additive value of LIS to predict ARDS outcomes over the recent Berlin definition of ARDS, which incorporates severity, is not known. Method
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od_______325::67f197f319f9d0cb06dafc3205d54fc3
http://www.escholarship.org/uc/item/2763j360
http://www.escholarship.org/uc/item/2763j360
Autor:
Matthay, Michael, Calfee, Carolyn, Ware, LB, Koyama, T, Zhao, Z, Janz, DR, Wickersham, N, Bernard, GR, May, AK, Calfee, CS, Matthay, MA
Publikováno v:
Matthay, Michael; Calfee, Carolyn; Ware, LB; Koyama, T; Zhao, Z; Janz, DR; et al.(2013). Biomarkers of lung epithelial injury and inflammation distinguish severe sepsis patients with acute respiratory distress syndrome. UC San Francisco: Retrieved from: http://www.escholarship.org/uc/item/50b61889
Introduction: Despite recent modifications, the clinical definition of the acute respiratory distress syndrome (ARDS) remains non-specific, leading to under-diagnosis and under-treatment. This study was designed to test the hypothesis that a biomarke
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od_______325::07f22f0fc9b5ec6b4c427da4872f2759
http://www.escholarship.org/uc/item/50b61889
http://www.escholarship.org/uc/item/50b61889
Publikováno v:
Calfee, Carolyn; Spicer, A; & Calfee, CS. (2012). Fixing the leak: targeting the vascular endothelium in sepsis. UC San Francisco: Retrieved from: http://www.escholarship.org/uc/item/1fm962sm
Angiopoietin-1 is a Tie-2 receptor agonist that stabilizes vascular endothelium, promoting endothelial maturation and preventing capillary leak. Angiopoietin-2 is largely a competitive partial antagonist that is markedly elevated in humans and animal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od_______325::9306405f1552dbd6109b33c147e367fa
http://www.escholarship.org/uc/item/1fm962sm
http://www.escholarship.org/uc/item/1fm962sm