Zobrazeno 1 - 10
of 75
pro vyhledávání: '"Calen P. Ryan"'
Autor:
Akshay Bareja, David E. Lee, Tricia Ho, Greg Waitt, Lauren H. McKay, Sarah A. Hannou, Melissa C. Orenduff, Kristen M. McGreevy, Alexandra Binder, Calen P. Ryan, Erik J. Soderblom, Daniel W. Belsky, Luigi Ferrucci, Jayanta Kumar Das, Nirad Banskota, Virginia B. Kraus, Janet L. Huebner, William E. Kraus, Kim M. Huffman, Gurpreet S. Baht, Steve Horvath, Robert J. Parmer, Lindsey A. Miles, James P. White
Publikováno v:
Cell Reports, Vol 43, Iss 3, Pp 113881- (2024)
Summary: An intriguing effect of short-term caloric restriction (CR) is the expansion of certain stem cell populations, including muscle stem cells (satellite cells), which facilitate an accelerated regenerative program after injury. Here, we utilize
Externí odkaz:
https://doaj.org/article/427aacba1e9c45278727a51ef1f744a6
Autor:
Christopher W. Kuzawa, Calen P. Ryan, Linda S. Adair, Nanette R. Lee, Delia B. Carba, Julia L. MacIsaac, Kristy Dever, Parmida Atashzay, Michael S. Kobor, Thomas W. McDade
Publikováno v:
Epigenetics, Vol 17, Iss 11, Pp 1535-1545 (2022)
Epigenetic clocks quantify regular changes in DNA methylation that occur with age, or in relation to biomarkers of ageing, and are strong predictors of morbidity and mortality. Here, we assess whether measures of fetal nutrition and growth that predi
Externí odkaz:
https://doaj.org/article/e496b37a6a674f3aaede8da3bf3c2488
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-13 (2020)
Abstract Understanding factors contributing to variation in ‘biological age’ is essential to understanding variation in susceptibility to disease and functional decline. One factor that could accelerate biological aging in women is reproduction.
Externí odkaz:
https://doaj.org/article/27e4ba3472bb491a91e560cf05395dc0
Autor:
Christopher W. Kuzawa, Linda Adair, Sonny A. Bechayda, Judith Rafaelita B. Borja, Delia B. Carba, Paulita L. Duazo, Dan T. A. Eisenberg, Alexander V. Georgiev, Lee T. Gettler, Nanette R. Lee, Elizabeth A. Quinn, Stacy Rosenbaum, Julienne N. Rutherford, Calen P. Ryan, Thomas W. McDade
Publikováno v:
Annals of Human Biology, Vol 47, Iss 2, Pp 94-105 (2020)
By tracking a group of individuals through time, cohort studies provide fundamental insights into the developmental time course and causes of health and disease. Evolutionary life history theory seeks to explain patterns of growth, development, repro
Externí odkaz:
https://doaj.org/article/52905d0ed1e946ddb5ab9c55b1bc0511
Autor:
Calen P Ryan, Christopher W Kuzawa
Publikováno v:
eLife, Vol 10 (2021)
In a population of wild baboons, a new way to assess biological age reveals a surprising effect of social hierarchy.
Externí odkaz:
https://doaj.org/article/06e25a7a9d204b6fbd1b8a5efaad67f2
Publikováno v:
Austral Entomology. 61:370-377
Autor:
Aline Thomas, Calen P Ryan, Avshalom Caspi, Terrie E Moffitt, Karen Sugden, Jiayi Zhou, Daniel W Belsky, Yian Gu
INTRODUCTION: We tested the hypothesis that healthy diet protects against dementia because it slows the pace of biological aging. METHODS: We analyzed Framingham Offspring Cohort data (≥60y). We measured healthy diet using the Dietary Guideline for
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::11903e251dea5bddf2677924a9300dc3
https://doi.org/10.1101/2023.05.24.23290474
https://doi.org/10.1101/2023.05.24.23290474
Autor:
Calen P. Ryan, Raviraj J. Rege, Nanette R. Lee, Delia B. Carba, Michael S. Kobor, Julie L. MacIsaac, David S. Lin, Parmida Atashzay, Christopher W. Kuzawa
Publikováno v:
Clinical epigenetics. 14(1)
Adverse birth outcomes, such as early gestational age and low birth weight, can have lasting effects on morbidity and mortality, with impacts that persist into adulthood. Identifying the maternal factors that contribute to adverse birth outcomes in t
Autor:
Calen P. Ryan, Bernard J. Crespi
Publikováno v:
Evolutionary Applications, Vol 6, Iss 2, Pp 180-196 (2013)
Abstract Variation in polyglutamine repeat number in the androgen receptor (AR CAGn) is negatively correlated with the transcription of androgen‐responsive genes and is associated with susceptibility to an extensive list of human disease. Only a sm
Externí odkaz:
https://doaj.org/article/a0a550e2785f42df96f378d27293d52c
Autor:
Calen P. Ryan, Christopher W. Kuzawa
Publikováno v:
Evolutionary Anthropology: Issues, News, and Reviews. 29:180-200
Recently, novel experimental approaches and molecular techniques have demonstrated that a male's experiences can be transmitted through his germline via epigenetic processes. These findings suggest that paternal exposures influence phenotypic variati