Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Caleb Sutherland"'
Autor:
K. Saidas Nair, Chitrangda Srivastava, Robert V. Brown, Swanand Koli, Hélène Choquet, Hong Soon Kang, Yien-Ming Kuo, Sara A. Grimm, Caleb Sutherland, Alexandra Badea, G. Allan Johnson, Yin Zhao, Jie Yin, Kyoko Okamoto, Graham Clark, Terete Borrás, Gulab Zode, Krishnakumar Kizhatil, Subhabrata Chakrabarti, Simon W. M. John, Eric Jorgenson, Anton M. Jetten
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-15 (2021)
Dysfunction of the trabecular meshwork (TM) is the chief cause of elevated intraocular pressure, the major risk factor of glaucoma. Here, the authors identify the transcription factor, GLIS1, as a critical regulator of TM maintenance and intraocular
Externí odkaz:
https://doaj.org/article/1d13ccf102314720a834e165f6b1a62d
Autor:
Ken Tawara, Celeste Bolin, Jordan Koncinsky, Sujatha Kadaba, Hunter Covert, Caleb Sutherland, Laura Bond, Joseph Kronz, Joel R. Garbow, Cheryl L. Jorcyk
Publikováno v:
Breast Cancer Research, Vol 20, Iss 1, Pp 1-18 (2018)
Abstract Background Systemic and chronic inflammatory conditions in patients with breast cancer have been associated with reduced patient survival and increased breast cancer aggressiveness. This paper characterizes the role of an inflammatory cytoki
Externí odkaz:
https://doaj.org/article/fb74ac45e62e44ca86a89521bb7e82be
Publikováno v:
Journal of the American Chemical Society. 138:14138-14151
MYC is overexpressed in many different cancer types and is an intensively studied oncogene because of its contributions to tumorigenesis. The regulation of MYC is complex, and the NHE III1 and FUSE elements rely upon noncanonical DNA structures and t
Autor:
Ramesh C. Kovi, Yu Wang, Caleb Sutherland, Anton M. Jetten, Beth W. Mahler, Kyathanahalli S. Janardhan, Julie F. Foley, Robert V. Brown
Publikováno v:
Journal of visualized experiments : JoVE. (136)
Laser capture microdissection (LCM) has allowed gene expression analysis of single cells and enriched cell populations in tissue sections. LCM is a great tool for the study of the molecular mechanisms underlying cell differentiation and the developme
Publikováno v:
Journal of the American Chemical Society. 138(42)
MYC is overexpressed in many different cancer types and is an intensively studied oncogene because of its contributions to tumorigenesis. The regulation of MYC is complex, and the NHE III
Autor:
Jeff Redshaw, Patrick S. Aranda, Celeste Bolin, Cheryl L. Jorcyk, Jim Moselhy, Robin L. Anderson, Ken Tawara, Caleb Sutherland
Publikováno v:
Genescancer. 3(2)
Oncostatin M (OSM) is an interleukin-6 (IL-6) family cytokine that has been implicated in a number of biological processes including inflammation, hematopoiesis, immune responses, development, and bone homeostasis. Recent evidence suggests that OSM m
Autor:
Laurence H. Hurley, Caleb Sutherland
Publikováno v:
Cancer Research. 75:2078-2078
MYC is overexpressed in most types of tumors, but a means to selectively decrease its expression has yet to be found. Our recent findings on modulation of bcl-2 gene expression through protein interactions with the bcl-2 i-motif have provided a basis
Publikováno v:
Biological Procedures
Biological Procedures Online, Vol 14, Iss 1, p 6 (2012)
Biological Procedures Online, Vol 14, Iss 1, p 6 (2012)
Background Tumor cell lines that can be tracked in vivo during tumorigenesis and metastasis provide vital tools for studying the specific cellular mechanisms that mediate these processes as well as investigating therapeutic targets to inhibit them. T
Publikováno v:
Cancer Research. 71:1469-1469
Oncostatin M (OSM) is an interleukin-6 (IL-6)-family cytokine that has been implicated in a number of biological processes including the induction of inflammation and modulation of the extracellular matrix. OSM was initially shown to inhibit the prol