Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Caleb M. Dillingham"'
Publikováno v:
Journal of Biological Chemistry. 294:5408-5419
α-Ketoglutarate is an important metabolic intermediate that acts as a cofactor for several chromatin-modifying enzymes, including histone demethylases and the Tet family of enzymes that are involved in DNA demethylation. In this review, we focus on
Autor:
Swati Rawat, Satori A. Marchitti, Christopher S. Mazur, Jason Zastre, Caleb M. Dillingham, Anshika Sharma, John F. Kenneke
Publikováno v:
Toxicological Sciences. 155:270-282
High body burdens of polybrominated diphenyl ethers (PBDEs) in infants and young children have led to increased concern over their potential impact on human development. PBDE exposure can alter the expression of genes involved in thyroid homeostasis,
Publikováno v:
EMBO J
Epigenetic modifications operate in concert to maintain cell identity, yet how these interconnected networks suppress alternative cell fates remains unknown. Here, we uncover a link between the removal of repressive histone H3K9 methylation and DNA m
Publikováno v:
Chirality. 28:633-641
Enantiomers of chiral molecules commonly exhibit differing pharmacokinetics and toxicities, which can introduce significant uncertainty when evaluating biological and environmental fates and potential risks to humans and the environment. However, rac
Publikováno v:
Chirality. 28(9)
Enantiomers of chiral molecules commonly exhibit differing pharmacokinetics and toxicities, which can introduce significant uncertainty when evaluating biological and environmental fates and potential risks to humans and the environment. However, rac