Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Caleb J. Hintz"'
Autor:
Corey L Anderson, Catherine E Kuzmicki, Ryan R Childs, Caleb J Hintz, Craig T January, Ravi C Balijepalli
Publikováno v:
Circulation. 132
Introduction: Hundreds of HERG potassium channel mutations are linked to type 2 Long QT Syndrome (LQT2). Most mutations are trafficking defective but correctable by culturing cells at reduced temperature (27 C) or with the pore blocker E4031. For a f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7bafca69f4142f4fd733c3a7cefc53e0
https://doi.org/10.1161/circ.132.suppl_3.16522
https://doi.org/10.1161/circ.132.suppl_3.16522
Autor:
Catherine E. Kuzmicki, Craig T. January, Corey L. Anderson, Caleb J. Hintz, Brian P. Delisle, Ryan R. Childs
Publikováno v:
Nature communications
It has been suggested that deficient protein trafficking to the cell membrane is the dominant mechanism associated with type 2 Long QT syndrome (LQT2) caused by Kv11.1 potassium channel missense mutations, and that for many mutations the trafficking
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1c5ef73743fdcdeb4f2c0183455fe412
https://pubmed.ncbi.nlm.nih.gov/25417810
https://pubmed.ncbi.nlm.nih.gov/25417810