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of 3
pro vyhledávání: '"Caleb González"'
Autor:
Caleb González, Joe Christian J Ray, Michael Manhart, Rhys M Adams, Dmitry Nevozhay, Alexandre V Morozov, Gábor Balázsi
Publikováno v:
Molecular Systems Biology, Vol 11, Iss 8, Pp 1-18 (2015)
Abstract Stress response genes and their regulators form networks that underlie drug resistance. These networks often have an inherent tradeoff: their expression is costly in the absence of stress, but beneficial in stress. They can quickly emerge in
Externí odkaz:
https://doaj.org/article/e7e0704efa474e2d9d4e7fed059a2ef5
Autor:
Caleb Gonzalez, Sarah Williamson, Seth T. Gammon, Sarah Glazer, Joon Haeng Rhee, David Piwnica-Worms
Publikováno v:
Communications Biology, Vol 6, Iss 1, Pp 1-15 (2023)
TLR5 agonists in combination with immune checkpoint therapies (ICT) enhance survival in ICT-refractory murine 4T1 mammary carcinoma and B16-F10 melanoma tumors. Low serum levels of G-CSF and CXCL5 correlate with enhanced survival.
Externí odkaz:
https://doaj.org/article/6dc5838505b34483b4b87174e299a4c5
Autor:
Caleb Gonzalez, Lilach Hadany, Rebecca G Ponder, Mellanie Price, P J Hastings, Susan M Rosenberg
Publikováno v:
PLoS Genetics, Vol 4, Iss 10, p e1000208 (2008)
In bacterial, yeast, and human cells, stress-induced mutation mechanisms are induced in growth-limiting environments and produce non-adaptive and adaptive mutations. These mechanisms may accelerate evolution specifically when cells are maladapted to
Externí odkaz:
https://doaj.org/article/3fe321de799644c5a43a85e3b8b8939d