Zobrazeno 1 - 10
of 29
pro vyhledávání: '"Caleb, Gonzalez"'
Autor:
Caleb Gonzalez, Sarah Williamson, Seth T. Gammon, Sarah Glazer, Joon Haeng Rhee, David Piwnica-Worms
Publikováno v:
Communications Biology, Vol 6, Iss 1, Pp 1-15 (2023)
TLR5 agonists in combination with immune checkpoint therapies (ICT) enhance survival in ICT-refractory murine 4T1 mammary carcinoma and B16-F10 melanoma tumors. Low serum levels of G-CSF and CXCL5 correlate with enhanced survival.
Externí odkaz:
https://doaj.org/article/6dc5838505b34483b4b87174e299a4c5
Autor:
David Piwnica-Worms, Jayne Marasa, Hongtu Zhu, Yue Wang, Brandon Kocher, Caleb Gonzalez, Kelly Flentie
Supplementary Table 1. Library Hits.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1aa866248c3f5722b1fb893d884bba9f
https://doi.org/10.1158/1541-7786.22515574.v1
https://doi.org/10.1158/1541-7786.22515574.v1
Autor:
David Piwnica-Worms, Jayne Marasa, Hongtu Zhu, Yue Wang, Brandon Kocher, Caleb Gonzalez, Kelly Flentie
Supplementary Figures 1-8. Figure S1. Dosed-dependent activation of transcriptionally-activated κB5:FLuc reporter by flagellin and heat-killed Salmonella in HCT116 colon carcinoma cells. Figure S2. Inhibition of the transcriptionally-coupled κB5:I
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b5b0a4629b8db40d9e896e1089f42835
https://doi.org/10.1158/1541-7786.22515577
https://doi.org/10.1158/1541-7786.22515577
Publikováno v:
Self+Culture+Writing: Autoethnography for/as Writing Studies
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4dff98303146d6f8e626f37d1d742595
https://doi.org/10.7330/9781646421213.c009
https://doi.org/10.7330/9781646421213.c009
Autor:
Brandon Kocher, Hongtu Zhu, David Piwnica-Worms, Yue Wang, Jayne Marasa, Kelly Flentie, Caleb Gonzalez
Publikováno v:
Molecular Cancer Research. 16:986-999
Bacterial flagellin is a potent activator of NFκB signaling, inflammation, and host innate immunity, and recent data indicate that flagellin represents a novel antitumor ligand acting through toll-like receptor 5 (TLR5) and the NFκB pathway to indu
Autor:
Caleb Gonzalez, Lilach Hadany, Rebecca G Ponder, Mellanie Price, P J Hastings, Susan M Rosenberg
Publikováno v:
PLoS Genetics, Vol 4, Iss 10, p e1000208 (2008)
In bacterial, yeast, and human cells, stress-induced mutation mechanisms are induced in growth-limiting environments and produce non-adaptive and adaptive mutations. These mechanisms may accelerate evolution specifically when cells are maladapted to
Externí odkaz:
https://doaj.org/article/3fe321de799644c5a43a85e3b8b8939d
Publikováno v:
Cancer Research. 80:921-921
Despite the success of immune checkpoint therapies (ICT) in achieving durable responses in subsets of cancer patients, not all patients respond to these types of therapies. Primary and adaptive resistance to immunotherapies present a considerable obs
Autor:
Kelly, Flentie, Caleb, Gonzalez, Brandon, Kocher, Yue, Wang, Hongtu, Zhu, Jayne, Marasa, David, Piwnica-Worms
Publikováno v:
Molecular cancer research : MCR. 16(6)
Bacterial flagellin is a potent activator of NFκB signaling, inflammation, and host innate immunity, and recent data indicate that flagellin represents a novel antitumor ligand acting through toll-like receptor 5 (TLR5) and the NFκB pathway to indu
Publikováno v:
Cancer Research. 76:4880-4880
Bacterial flagellin is a potent activator of NF-êB signaling, inflammation and host innate immunity. In comparison to TNFá, perhaps the most studied NF-êB-inducing ligand, flagellin elicits an overlapping, yet unique downstream transcriptional res
Autor:
Claude Saint-Ruf, Caleb Gonzalez, Olivier Lichtarge, Ryan L. Frisch, Andreas Martin Lisewski, Abu Amar M. Al Mamun, Ralf B. Nehring, P. J. Hastings, Mary Jane Lombardo, Dong Xu Lin, Chandan Shee, Janet L. Gibson, Susan M. Rosenberg
Publikováno v:
Science
Science, American Association for the Advancement of Science, 2012, 338 (6112), pp.1344-8. ⟨10.1126/science.1226683⟩
Science, American Association for the Advancement of Science (AAAS), 2012, 338 (6112), pp.1344-8. ⟨10.1126/science.1226683⟩
Science, American Association for the Advancement of Science, 2012, 338 (6112), pp.1344-8. ⟨10.1126/science.1226683⟩
Science, American Association for the Advancement of Science (AAAS), 2012, 338 (6112), pp.1344-8. ⟨10.1126/science.1226683⟩
Sewing Up DNA Repair All cells have a battery of DNA-repair pathways to help ensure genome maintenance and stability, including stress-induced DNA break repair in Escherichia coli. Similar pathways—which can be mutagenic—are known in yeast and hu