Functional connectivity differences of the olfactory network in Parkinson's Disease, mild cognitive impairment and cognitively normal individuals: A resting-state fMRI study.

Autor: Cieri F; Department of Neurology, Cleveland Clinic Lou Ruvo Center for Brain Health, Las Vegas, NV 89106, USA. Electronic address: cierif3@ccf.org., Giriprakash PP; Department of Neurology, Cleveland Clinic Lou Ruvo Center for Brain Health, Las Vegas, NV 89106, USA., Nandy R; Department of Biostatistics & Epidemiology, University of North Texas Health Science Center, Fort Worth, TX, USA., Zhuang X; Department of Neurology, Cleveland Clinic Lou Ruvo Center for Brain Health, Las Vegas, NV 89106, USA., Doty RL; Smell and Taste Center, Department of Otorhinolaryngology, Head and Neck Surgery, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA., Caldwell JZK; Department of Neurology, Cleveland Clinic Lou Ruvo Center for Brain Health, Las Vegas, NV 89106, USA., Cordes D; Department of Neurology, Cleveland Clinic Lou Ruvo Center for Brain Health, Las Vegas, NV 89106, USA; Department of Psychology and Neuroscience, University of Colorado, Boulder, CO 80309, USA.

Publikováno v: Neuroscience [Neuroscience] 2024 Nov 01; Vol. 559, pp. 8-16. Date of Electronic Publication: 2024 Aug 22.

Systematic characterization of multi-omics landscape between gut microbial metabolites and GPCRome in Alzheimer's disease.

Autor: Qiu Y; Cleveland Clinic Genome Center, Lerner Research Institute, Cleveland Clinic, Cleveland, OH 44195, USA; Genomic Medicine Institute, Lerner Research Institute, Cleveland Clinic, Cleveland, OH 44195, USA., Hou Y; Cleveland Clinic Genome Center, Lerner Research Institute, Cleveland Clinic, Cleveland, OH 44195, USA; Genomic Medicine Institute, Lerner Research Institute, Cleveland Clinic, Cleveland, OH 44195, USA., Gohel D; Cleveland Clinic Genome Center, Lerner Research Institute, Cleveland Clinic, Cleveland, OH 44195, USA; Genomic Medicine Institute, Lerner Research Institute, Cleveland Clinic, Cleveland, OH 44195, USA., Zhou Y; Cleveland Clinic Genome Center, Lerner Research Institute, Cleveland Clinic, Cleveland, OH 44195, USA; Genomic Medicine Institute, Lerner Research Institute, Cleveland Clinic, Cleveland, OH 44195, USA., Xu J; Cleveland Clinic Genome Center, Lerner Research Institute, Cleveland Clinic, Cleveland, OH 44195, USA; Genomic Medicine Institute, Lerner Research Institute, Cleveland Clinic, Cleveland, OH 44195, USA., Bykova M; Cleveland Clinic Genome Center, Lerner Research Institute, Cleveland Clinic, Cleveland, OH 44195, USA; Genomic Medicine Institute, Lerner Research Institute, Cleveland Clinic, Cleveland, OH 44195, USA., Yang Y; Cleveland Clinic Genome Center, Lerner Research Institute, Cleveland Clinic, Cleveland, OH 44195, USA; Genomic Medicine Institute, Lerner Research Institute, Cleveland Clinic, Cleveland, OH 44195, USA., Leverenz JB; Lou Ruvo Center for Brain Health, Neurological Institute, Cleveland Clinic, Cleveland, OH 44195, USA; Department of Molecular Medicine, Cleveland Clinic Lerner College of Medicine, Case Western Reserve University, Cleveland, OH 44195, USA., Pieper AA; Brain Health Medicines Center, Harrington Discovery Institute, University Hospitals Cleveland Medical Center, Cleveland, OH 44106, USA; Department of Psychiatry, Case Western Reserve University, Cleveland, OH 44106, USA; Geriatric Psychiatry, GRECC, Louis Stokes Cleveland VA Medical Center, Cleveland, OH 44106, USA; Institute for Transformative Molecular Medicine, School of Medicine, Case Western Reserve University, Cleveland, OH 44106, USA; Department of Neurosciences, Case Western Reserve University, School of Medicine, Cleveland, OH 44106, USA; Department of Pathology, Case Western Reserve University, School of Medicine, Cleveland, OH 44106, USA., Nussinov R; Computational Structural Biology Section, Frederick National Laboratory for Cancer Research in the Cancer Innovation Laboratory, National Cancer Institute, Frederick, MD 21702, USA; Department of Human Molecular Genetics and Biochemistry, Sackler School of Medicine, Tel Aviv University, Tel Aviv 69978, Israel., Caldwell JZK; Department of Molecular Medicine, Cleveland Clinic Lerner College of Medicine, Case Western Reserve University, Cleveland, OH 44195, USA; Lou Ruvo Center for Brain Health, Neurological Institute, Cleveland Clinic, Las Vegas, NV 89106, USA., Brown JM; Department of Molecular Medicine, Cleveland Clinic Lerner College of Medicine, Case Western Reserve University, Cleveland, OH 44195, USA; Department of Cancer Biology, Lerner Research Institute Cleveland Clinic, Cleveland, OH 44195, USA; Center for Microbiome and Human Health, Lerner Research Institute, Cleveland Clinic, Cleveland, OH 44195, USA., Cheng F; Cleveland Clinic Genome Center, Lerner Research Institute, Cleveland Clinic, Cleveland, OH 44195, USA; Genomic Medicine Institute, Lerner Research Institute, Cleveland Clinic, Cleveland, OH 44195, USA; Department of Molecular Medicine, Cleveland Clinic Lerner College of Medicine, Case Western Reserve University, Cleveland, OH 44195, USA; Case Comprehensive Cancer Center, Case Western Reserve University, School of Medicine, Cleveland, OH 44106, USA. Electronic address: chengf@ccf.org.

Publikováno v: Cell reports [Cell Rep] 2024 May 28; Vol. 43 (5), pp. 114128. Date of Electronic Publication: 2024 Apr 21.

Microglial immunometabolism endophenotypes contribute to sex difference in Alzheimer's disease.

Autor: Hou Y; Genomic Medicine Institute, Cleveland Clinic, Lerner Research Institute, Cleveland, Ohio, USA., Caldwell JZK; Department of Molecular Medicine, Cleveland Clinic Lerner College of Medicine, Case Western Reserve University, Cleveland, Ohio, USA.; Lou Ruvo Center for Brain Health, Cleveland Clinic, Neurological Institute, Las Vegas, Nevada, USA., Lathia JD; Department of Molecular Medicine, Cleveland Clinic Lerner College of Medicine, Case Western Reserve University, Cleveland, Ohio, USA.; Department of Cardiovascular & Metabolic Science, Cleveland Clinic, Lerner Research Institute, Cleveland, Ohio, USA., Leverenz JB; Lou Ruvo Center for Brain Health, Cleveland Clinic, Neurological Institute, Cleveland, Ohio, USA., Pieper AA; Brain Health Medicines Center, Harrington Discovery Institute, University Hospitals Cleveland Medical Center, Cleveland, Ohio, USA.; Department of Psychiatry, Case Western Reserve University, Cleveland, Ohio, USA.; Geriatric Psychiatry, GRECC, Louis Stokes Cleveland VA Medical Center, Cleveland, Ohio, USA.; Institute for Transformative Molecular Medicine, School of Medicine, Case Western Reserve University, Cleveland, Ohio, USA.; Department of Neurosciences, School of Medicine, Case Western Reserve University, Cleveland, Ohio, USA.; Department of Pathology, School of Medicine, Case Western Reserve University, Cleveland, Ohio, USA., Cummings J; Chambers-Grundy Center for Transformative Neuroscience, Department of Brain Health, School of Integrated Health Sciences, University of Nevada Las Vegas, Las Vegas, Nevada, USA., Cheng F; Genomic Medicine Institute, Cleveland Clinic, Lerner Research Institute, Cleveland, Ohio, USA.; Department of Molecular Medicine, Cleveland Clinic Lerner College of Medicine, Case Western Reserve University, Cleveland, Ohio, USA.

Publikováno v: Alzheimer's & dementia : the journal of the Alzheimer's Association [Alzheimers Dement] 2024 Feb; Vol. 20 (2), pp. 1334-1349. Date of Electronic Publication: 2023 Nov 20.

Cognitive aging in rural communities: preliminary memory characterization of a community cohort from Southern Nevada.

Autor: Miller JB; Cleveland Clinic Lou Ruvo Center for Brain Health, Las Vegas, NV, United States., Wong CG; Cleveland Clinic Lou Ruvo Center for Brain Health, Las Vegas, NV, United States., Caldwell JZK; Cleveland Clinic Lou Ruvo Center for Brain Health, Las Vegas, NV, United States., Rodrigues J; Cleveland Clinic Lou Ruvo Center for Brain Health, Las Vegas, NV, United States., Pudumjee S; Cleveland Clinic Lou Ruvo Center for Brain Health, Las Vegas, NV, United States., John SE; Department of Brain Health, University of Nevada, Las Vegas, NV, United States., Ritter A; Memory & Cognitive Disorders Program, Hoag Hospital, Pickup Family Neurosciences Institute, Newport Beach, CA, United States.

Publikováno v: Frontiers in dementia [Front Dement] 2023 Aug 24; Vol. 2, pp. 1236039. Date of Electronic Publication: 2023 Aug 24 (Print Publication: 2023).

Olfaction and Anxiety Are Differently Associated in Men and Women in Cognitive Physiological and Pathological Aging.

Autor: Cieri F; Department of Neurology, Cleveland Clinic Lou Ruvo Center for Brain Health, Las Vegas, NV 89106, USA., Cera N; Laboratory of Neuropsychophysiology, Faculty of Psychology and Education Sciences, University of Porto, 4200-135 Porto, Portugal.; CIBIT-Coimbra Institute for Biomedical Imaging and Translational Research, University of Coimbra, 3000-548 Coimbra, Portugal., Ritter A; Department of Neurology, Cleveland Clinic Lou Ruvo Center for Brain Health, Las Vegas, NV 89106, USA., Cordes D; Department of Neurology, Cleveland Clinic Lou Ruvo Center for Brain Health, Las Vegas, NV 89106, USA.; Department of Brain Health, University of Nevada, Las Vegas, NV 89154, USA.; Department of Psychology and Neuroscience, University of Colorado, Boulder, CO 80309, USA., Caldwell JZK; Department of Neurology, Cleveland Clinic Lou Ruvo Center for Brain Health, Las Vegas, NV 89106, USA.

Publikováno v: Journal of clinical medicine [J Clin Med] 2023 Mar 17; Vol. 12 (6). Date of Electronic Publication: 2023 Mar 17.