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Methotrexate loaded SLN obtained by coacervation for potential glioblastoma treatment

Autor: Battaglia, L., Gallarate, M., Peira, E., Chirio, D., Gastaldi, L., Muntoni, E., Biasibetti, E., Capucchio, M. T., Valazza, A., Panciani, P., Lanotte, M., Schiffer, D., Annovazzi, L., Caldera, V., Riganti, C.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::ffdad0ce397442bec685bac836541d7b
http://hdl.handle.net/2318/155385

Temozolomide down-regulates P-glycoprotein expression in glioblastoma stem cells by interfering with the Wnt3a/GSK3/β-catenin pathway

Autor: Riganti, Chiara, Salaroglio, IRIS CHIARA, Caldera, V., Campia, Ivana, Kopecka, Joanna, Mellai, M., Annovazzi, L., Bosia, Amalia, Ghigo, Dario Antonio, Schiffer, Davide

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od_______970::08440a84fa555229c4daffb5c5711932
http://hdl.handle.net/2318/139469

DNA damage and repair in glioblastoma cell lines after antitumor drugs

Autor: Annovazzi, L, Caldera, V, Mellai, M, Piazzi, A, Monzeglio, O, Schiffer, D

Publikováno v: 57th Annual Meeting of the German Society for Neuropathology and Neuroanatomy (DGNN); 20120912-20120915; Erlangen; DOC12dgnnPP3.9 /20120911/

Glioblastoma cell resistance to chemotherapy is due mainly to the MDR efflux pump and to the impairment of DNA repair mechanisms such as MGMT and PARP1. Tumor stem cells are responsible for cell resistance. We studied in glioblastoma cell lines, neur

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::09389d4150488afa643dd0ae4a4c1b1a

MGMT promoter hypermethylation in a series of 104 glioblastomas

Autor: Mellai, M., Caldera, V., Annovazzi, L., Chiò, A., Lanotte, M., Cassoni, P., Gaetano Finocchiaro, Schiffer, D.

Publikováno v: Scopus-Elsevier

To evaluate MGMT promoter hypermethylation as prognostic factor in a retrospective study of 104 cases of glioblastoma multiforme (GBM).The O(6)-methylguanine-DNA methyltransferase (MGMT) status was evaluated by methylation-specific PCR (MSP), immunoh

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::9e8ae0a3a50a0b891b9c4eb52adc452d
http://hdl.handle.net/2318/120722