CIGB-300 Anticancer Peptide Differentially Interacts with CK2 Subunits and Regulates Specific Signaling Mediators in a Highly Sensitive Large Cell Lung Carcinoma Cell Model.

Autor: Pérez GV; Molecular Oncology Group, Department of Pharmaceuticals, Biomedical Research Division, Center for Genetic Engineering & Biotechnology (CIGB), Havana 10600, Cuba., Rosales M; Molecular Oncology Group, Department of Pharmaceuticals, Biomedical Research Division, Center for Genetic Engineering & Biotechnology (CIGB), Havana 10600, Cuba.; Department of Animal and Human Biology, Faculty of Biology, University of Havana (UH), Havana 10400, Cuba., Ramón AC; Molecular Oncology Group, Department of Pharmaceuticals, Biomedical Research Division, Center for Genetic Engineering & Biotechnology (CIGB), Havana 10600, Cuba., Rodríguez-Ulloa A; Mass Spectrometry Laboratory, Proteomics Group, Department of System Biology, Biomedical Research Division, CIGB, Havana 10600, Cuba., Besada V; Mass Spectrometry Laboratory, Proteomics Group, Department of System Biology, Biomedical Research Division, CIGB, Havana 10600, Cuba., González LJ; Mass Spectrometry Laboratory, Proteomics Group, Department of System Biology, Biomedical Research Division, CIGB, Havana 10600, Cuba., Aguilar D; Molecular Oncology Group, Department of Pharmaceuticals, Biomedical Research Division, Center for Genetic Engineering & Biotechnology (CIGB), Havana 10600, Cuba., Vázquez-Blomquist D; Pharmacogenomic Group, Department of System Biology, Biomedical Research Division, CIGB, Havana 10600, Cuba., Falcón V; Microscopy Laboratory, Department of System Biology, Biomedical Research Division, CIGB, Havana 10600, Cuba., Caballero E; Molecular Oncology Group, Department of Pharmaceuticals, Biomedical Research Division, Center for Genetic Engineering & Biotechnology (CIGB), Havana 10600, Cuba., Carvalho PC; Laboratory for Structural and Computational Proteomics, Carlos Chagas Institute, Fiocruz-Paraná, R. Professor Algacyr Munhoz Mader 3775, Curitiba 81310-020, PR, Brazil., Caldeira RS; Mass Spectrometry Facility, Carlos Chagas Institute, Fiocruz-Paraná, R. Professor Algacyr Munhoz Mader 3775, Curitiba 81310-020, PR, Brazil., Yang K; China-Cuba Biotechnology Joint Innovation Center (CCBJIC), Yongzhou Zhong Gu Biotechnology, Yongzhou 425000, China., Perera Y; Molecular Oncology Group, Department of Pharmaceuticals, Biomedical Research Division, Center for Genetic Engineering & Biotechnology (CIGB), Havana 10600, Cuba.; China-Cuba Biotechnology Joint Innovation Center (CCBJIC), Yongzhou Zhong Gu Biotechnology, Yongzhou 425000, China., Perea SE; Molecular Oncology Group, Department of Pharmaceuticals, Biomedical Research Division, Center for Genetic Engineering & Biotechnology (CIGB), Havana 10600, Cuba.

Publikováno v: Biomedicines [Biomedicines] 2022 Dec 25; Vol. 11 (1). Date of Electronic Publication: 2022 Dec 25.