Zobrazeno 1 - 10
of 980
pro vyhledávání: '"Calcium transient"'
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-12 (2024)
Abstract Dexmedetomidine (DEX) is commonly used in clinical practice because of its sedative, analgesic, antisympathetic, hemodynamic stabilization and antianxiety effects. Previous clinical studies have demonstrated that DEX plays a role in both the
Externí odkaz:
https://doaj.org/article/eeb8f710a18449259ab2efb75e6f378a
Autor:
Yuki Tatekoshi, Chunlei Chen, Jason Solomon Shapiro, Hsiang-Chun Chang, Malorie Blancard, Davi M Lyra-Leite, Paul W Burridge, Matthew Feinstein, Richard D'Aquila, Priscilla Hsue, Hossein Ardehali
Publikováno v:
eLife, Vol 13 (2024)
Heart failure with preserved ejection fraction (HFpEF) is commonly found in persons living with HIV (PLWH) even when antiretroviral therapy suppresses HIV viremia. However, studying this condition has been challenging because an appropriate animal mo
Externí odkaz:
https://doaj.org/article/d554a4e305244435abefadbdb0b10274
Autor:
Mark Warren, Steven Poelzing
Publikováno v:
Frontiers in Physiology, Vol 15 (2024)
Cardiac action potential (AP) alternans have been linked to the development of arrhythmia. AP alternans may be driven by AP instabilities, Ca2+ transient (CaT) instabilities, or both. The mechanisms underlying CaT driven AP alternans is well-supporte
Externí odkaz:
https://doaj.org/article/7a82840bc28c40d9ab840a240d902cf3
Akademický článek
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Publikováno v:
Channels, Vol 16, Iss 1, Pp 97-112 (2022)
Carvedilol is a nonspecific β-blocker clinically used for the treatment of cardiovascular diseases but has also been shown to have profound effects on excitation-contraction coupling and Ca signaling at the cellular level. We investigate the mechani
Externí odkaz:
https://doaj.org/article/cdc090d434624dcdb5601ceeadd9a978
Autor:
Ana Julia Velez Rueda, Luis Alberto Gonano, Agustín García Smith, Gustavo Parisi, María Silvina Fornasari, Leandro Matías Sommese
Publikováno v:
Frontiers in Bioinformatics, Vol 3 (2023)
One of the main topics of cardiovascular research is the study of calcium (Ca2+) handling, as even small changes in Ca2+ concentration can alter cell functionality (Bers, Annu Rev Physiol, 2014, 76, 107–127). Ionic calcium (Ca2+) plays the role of
Externí odkaz:
https://doaj.org/article/505ad2137f0649e180c513117e0726bd
Akademický článek
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Publikováno v:
Frontiers in Cellular Neuroscience, Vol 17 (2023)
Activated glia are known to exhibit either neuroprotective or neurodegenerative effects, depending on their phenotype, while participating in chronic pain regulation. Until recently, it has been believed that satellite glial cells and astrocytes are
Externí odkaz:
https://doaj.org/article/cd6077d040ae4da8961fb2007b4cff98
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 11 (2023)
Background: We had shown that cardiomyocytes (CMs) were more efficiently differentiated from human induced pluripotent stem cells (hiPSCs) when the hiPSCs were reprogrammed from cardiac fibroblasts rather than dermal fibroblasts or blood mononuclear
Externí odkaz:
https://doaj.org/article/598613ae2358421caa772939d51d9ed9
Akademický článek
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