Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Calcium channel opener"'
Publikováno v:
Cellular and Molecular Neurobiology. 41:1707-1714
The present study explored the modulating apoptosis effect of hydrogen sulfide (H2S) in subarachnoid hemorrhage (SAH) rats and its exact mechanism. A rat SAH model established by intravascular puncturing was used for the present study. After giving N
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::69a311c2138c36c8be1ecbe4320bf15b
https://doi.org/10.1007/s10571-020-00940-0
https://doi.org/10.1007/s10571-020-00940-0
Autor:
Yasutomo Kumakura, Tadahiko Ishiyama, Tetsuya Iijima, Masakazu Kotoda, Hirofumi Ino, Takashi Matsukawa
Publikováno v:
Journal of Pain Research. 12:1825-1832
Purpose: Although amiodarone is classified as a Vaughan-Williams class Ⅲ antiarrhythmic drug, it has inhibitory effects on voltage-gated sodium and calcium channels and on β-adrenergic receptors. Given these pharmacological profiles, amiodarone ma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5e64d76b0000126de2e6833712a1932e
https://doi.org/10.2147/jpr.s196480
https://doi.org/10.2147/jpr.s196480
Publikováno v:
European journal of pharmacology. 896
In order to gain insight into the regulation of vascular tone by mitochondria, the effects of mitochondrial complex III inhibitors on contractile responses in porcine isolated coronary arteries were investigated. Segments of porcine coronary arteries
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::199695f5c66815cbeed62e6750b842dd
https://pubmed.ncbi.nlm.nih.gov/33529727
https://pubmed.ncbi.nlm.nih.gov/33529727
Publikováno v:
Toxicological Sciences. 167:573-580
Calcium channel blockers (CCBs), such as diltiazem, nifedipine, and verapamil, cause tachycardia effects on several commercially available human-induced pluripotent stem cell-derived cardiomyocytes (hiPSC-CMs), when tested in culture media provided b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c7a0496ec1502cec63d4631efbab6d92
https://doi.org/10.1093/toxsci/kfy264
https://doi.org/10.1093/toxsci/kfy264
Publikováno v:
BioMed Research International, Vol 2017 (2017)
BioMed Research International
BioMed Research International
Calcium sensitization mediated by RhoA/Rho kinase pathway can be evaluated either in the absence (basal calcium sensitization) or in the presence of endogenous vasoconstrictor systems (activated calcium sensitization). Our aim was to compare basal an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9806a6fd14f787af5bf6dd2fc31285a1
https://doi.org/10.1155/2017/8029728
https://doi.org/10.1155/2017/8029728
Publikováno v:
Journal of Pharmacological and Toxicological Methods. 99:106598
We investigated whether human induced pluripotent stem cell-derived cardiomyocytes (hiPSC-CMs) created from diverse origins could have qualitatively (not just quantitatively) different responses to pharmacological reagents. Specifically, we challenge
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::789b676b8601a2b221ef2be386ae5ce4
https://doi.org/10.1016/j.vascn.2019.106598
https://doi.org/10.1016/j.vascn.2019.106598
Publikováno v:
Journal of Pharmacological and Toxicological Methods. 99:106595
Calcium channel blockers (CCBs), such as diltiazem, nifedipine, and verapamil, cause tachycardia effects on several commercially available human-induced pluripotent stem cell-derived cardiomyocytes (hiPSC-CMs), when tested in culture media provided b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d8eda03fcd850521f00e0fe42096935f
https://doi.org/10.1016/j.vascn.2019.05.158
https://doi.org/10.1016/j.vascn.2019.05.158
Publikováno v:
Naunyn-Schmiedeberg's Archives of Pharmacology. 371:152-157
It is now well known that 17beta-estradiol has an endothelium-independent, non-genomic vasorelaxant effect. We hypothesized that 17beta-estradiol has its non-genomic effect on calcium-independent contraction in de-endothelialized rat aortic rings. Ra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5aa2c4e1f1b18d2a0c0abf92537a26bd
https://doi.org/10.1007/s00210-004-1017-3
https://doi.org/10.1007/s00210-004-1017-3
Autor:
Olga Jilkina, Hee Jeong Kong, Bozena Kuzio, Valery Kupriyanov, Clifford D.L. Folmes, Gary J. Grover
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Biomembranes. 1618(1):39-50
We investigated consequences of cardiac arrest on sarcolemmal and mitochondrial effects of ATP-sensitive potassium channel (KATP) opener, P-1075, in Langendorff-perfused rat hearts. Depolarised cardiac arrest (24.7 mM KCl) did not affect glibenclamid
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3e814cac257f498586764d8a923d180c
Publikováno v:
Pharmacology & Toxicology. 92:226-233
Transmitter release from nerve terminals is dependent on the entry of Ca(2+) through neuronal voltage-gated calcium channels. In sympathetic neurones both N- and L-type calcium channels are present. Potassium channel blockade increases Ca(2+) entry i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::42cf52996bec5c072058d978b9a9c1ea
https://doi.org/10.1034/j.1600-0773.2003.920505.x
https://doi.org/10.1034/j.1600-0773.2003.920505.x