Zobrazeno 1 - 10
of 12 333
pro vyhledávání: '"Calcium Imaging"'
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-17 (2024)
Abstract Calcium imaging allows recording from hundreds of neurons in vivo with the ability to resolve single cell activity. Evaluating and analyzing neuronal responses, while also considering all dimensions of the data set to make specific conclusio
Externí odkaz:
https://doaj.org/article/7e48120f9ab8476ba2f4fb8abc17ccaa
Autor:
Ignacio Marin-Blasco, Giorgia Vanzo, Joaquin Rusco-Portabella, Lucas Perez-Molina, Leire Romero, Antonio Florido, Raul Andero
Publikováno v:
Biology of Sex Differences, Vol 15, Iss 1, Pp 1-14 (2024)
Abstract In recent years, research has progressively increased the importance of considering sex differences in stress and fear memory studies. Many studies have traditionally focused on male subjects, potentially overlooking critical differences wit
Externí odkaz:
https://doaj.org/article/12e1c1d0c1e5420aa3a796f575875d81
Autor:
Richard J. Amedzrovi Agbesi, Amira El Merhie, Nick J. Spencer, Tim Hibberd, Nicolas R. Chevalier
Publikováno v:
Experimental Physiology, Vol 109, Iss 9, Pp 1545-1556 (2024)
Abstract Gut motility undergoes a switch from myogenic to neurogenic control in late embryonic development. Here, we report on the electrical events that underlie this transition in the enteric nervous system, using the GCaMP6f reporter in neural cre
Externí odkaz:
https://doaj.org/article/d2583cf24722482ba9c6194c05a68133
Autor:
Tong Shen, Mingyu Du, Kevin Johnston, Steven F. Grieco, Rachel Crary, John F. Guzowski, Gyorgy Lur, Xiangmin Xu, Hernando Ombao, Michele Guindani, Zhaoxia Yu
Publikováno v:
Data Science in Science, Vol 3, Iss 1 (2024)
Optical imaging of genetically encoded calcium indicators is a powerful tool to record the activity of a large number of neurons simultaneously over a long period of time from freely behaving animals. However, determining the exact time at which a ne
Externí odkaz:
https://doaj.org/article/4eadd2b73c4a409e8f22b4168f4a824d
Publikováno v:
NeuroImage, Vol 298, Iss , Pp 120758- (2024)
Recent advances in calcium imaging, including the development of fast and sensitive genetically encoded indicators, high-resolution camera chips for wide-field imaging, and resonant scanning mirrors in laser scanning microscopy, have notably improved
Externí odkaz:
https://doaj.org/article/adb53fd99e02424683ba2490d01bcc55
Autor:
Navid S. Tavakoli, Samantha G. Malone, Tanner L. Anderson, Ryson E. Neeley, Artin Asadipooya, Michael T. Bardo, Pavel I. Ortinski
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 18 (2024)
Recent literature supports a prominent role for astrocytes in regulation of drug-seeking behaviors. The dorsal striatum, specifically, is known to play a role in reward processing with neuronal activity that can be influenced by astrocyte Ca2+. Howev
Externí odkaz:
https://doaj.org/article/ebc9ab46bd814c30abe0b689479360f2
Autor:
Josue M Regalado, Ariadna Corredera Asensio, Theresa Haunold, Andrew C Toader, Yan Ran Li, Lauren A Neal, Priyamvada Rajasethupathy
Publikováno v:
eLife, Vol 13 (2024)
Learning requires the ability to link actions to outcomes. How motivation facilitates learning is not well understood. We designed a behavioral task in which mice self-initiate trials to learn cue-reward contingencies and found that the anterior cing
Externí odkaz:
https://doaj.org/article/e80204c3dfe445acbc4b822b90b4cedc
Publikováno v:
eLife, Vol 12 (2024)
Synaptic inputs to cortical neurons are highly structured in adult sensory systems, such that neighboring synapses along dendrites are activated by similar stimuli. This organization of synaptic inputs, called synaptic clustering, is required for hig
Externí odkaz:
https://doaj.org/article/9923a54e4f324e68866ddbe81f020de9
Autor:
Christian Memo, Pietro Parisse, Roberta Amoriello, Maria Pachetti, Anabela Palandri, Loredana Casalis, Clara Ballerini, Laura Ballerini
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 18 (2024)
IntroductionNeuroinflammation is a hallmark of multiple neurodegenerative diseases, shared by all pathological processes which primarily impact on neurons, including Central Nervous System (CNS) injuries. In reactive CNS, activated glia releases extr
Externí odkaz:
https://doaj.org/article/5646c7cb959e46ec877db12f3b9c4340
Autor:
K. Suba, Y. Patel, A. Martin-Alonso, B. Hansen, X. Xu, A. Roberts, M. Norton, P. Chung, J. Shrewsbury, R. Kwok, V. Kalogianni, S. Chen, X. Liu, K. Kalyviotis, G.A. Rutter, B. Jones, J. Minnion, B.M. Owen, P. Pantazis, W. Distaso, D.J. Drucker, T.M. Tan, S.R. Bloom, K.G. Murphy, V. Salem
Publikováno v:
Molecular Metabolism, Vol 85, Iss , Pp 101947- (2024)
Objective: Type 2 diabetes (T2D) is characterised by the loss of first-phase insulin secretion. We studied mice with β-cell selective loss of the glucagon receptor (Gcgrfl/fl X Ins-1Cre), to investigate the role of intra-islet glucagon receptor (GCG
Externí odkaz:
https://doaj.org/article/c37ae5408a23406d8a7d1275751b2671