Výsledky vyhledávání - "Calcium Channels/metabolism"

Guard Cell-Specific Calcium Sensitivity of High Density and Activity SV/TPC1 Channels

Autor: Rainer Hedrich, Jörg Fromm, Florian Rienmüller, Edward E. Farmer, Irene Marten, Silke Lautner, Peter Ache, Khaled A. S. Al-Rasheid, Diana Beyhl

Publikováno v: Plant and Cell Physiology, vol. 51, no. 9, pp. 1548-1554

The slow vacuolar (SV) channel, a Ca 2 + -regulated vacuolar cation conductance channel, in Arabidopsis thaliana is encoded by the single-copy gene AtTPC1 . Although loss-offunction tpc1 mutants were reported to exhibit a stoma phenotype, knowledge a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1c2f2184eda65be25c62a28004cae10e
http://doc.rero.ch/record/302845/files/pcq102.pdf

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N-terminal tagging of human P2X7 receptor disturbs calcium influx and dye uptake

Autor: Niklas Rye Jørgensen, Birgitte Rahbek Kornum, Nikolaj Pagh Kristensen, Karin Dreisig, Maja Wallentin Dommer

Publikováno v: Dreisig, K, Kristensen, N P, Dommer, M W, Jørgensen, N R & Kornum, B R 2018, ' N-terminal tagging of human P2X7 receptor disturbs calcium influx and dye uptake ', Purinergic Signalling, vol. 14, no. 1, pp. 83–90 . https://doi.org/10.1007/s11302-017-9598-8

The P2X7 receptor is a frequently studied member of the purinergic receptor family signalling via channel opening and membrane pore formation. Fluorescent imaging is an important molecular method for studying cellular receptor expression and localiza

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5e3213e2e2246dda41ce8a0a3df74d5d
https://pubmed.ncbi.nlm.nih.gov/29290027

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Hypoxic pulmonary vasoconstriction requires connexin 40–mediated endothelial signal conduction

Autor: Jun Yin, Marc Chanson, Wolfgang M. Kuebler, Julia Hoffmann, Hermann Kuppe, Brenda R. Kwak, Hannah T. Nickles, Eduardo Barbosa-Sicard, Martin Witzenrath, Liming Wang, Hee-Sup Shin, Arata Tabuchi, Songwei Wu, Brant E. Isakson, Hannes Ranke, Christoph Tabeling, Cor de Wit, Ingrid Fleming

Publikováno v: Journal of Clinical Investigation, Vol. 122, No 11 (2012) pp. 4218-30
The Journal of clinical investigation

Hypoxic pulmonary vasoconstriction (HPV) is a physiological mechanism by which pulmonary arteries constrict in hypoxic lung areas in order to redirect blood flow to areas with greater oxygen supply. Both oxygen sensing and the contractile response ar

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::52931087d4b5cb6aeb94c5c6f7465746
https://doi.org/10.1172/jci59176

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Connexin 43 Hemichannels Contribute to Cytoplasmic Ca2+ Oscillations by Providing a Bimodal Ca2+-dependent Ca2+ Entry Pathway

Autor: Geneviève Dupont, Mélissa Bol, Marijke De Bock, Nan Wang, Elke Decrock, Geert Bultynck, Luc Leybaert, Raf Ponsaerts

Publikováno v: The Journal of biological chemistry, 287 (15

Many cellular functions are driven by changes in the intracellular Ca(2+) concentration ([Ca(2+)](i)) that are highly organized in time and space. Ca(2+) oscillations are particularly important in this respect and are based on positive and negative [

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e7f1910a94e056b0e3a572bdcc2f5030
https://doi.org/10.1074/jbc.m111.299610

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Dual modulation of CNS voltage-gated calcium channels by cannabinoids

Publikováno v: Cell Calcium. 46(3):154-162

The neuromodulatory effects of cannabinoids in the central nervous system have mainly been associated with G-protein coupled cannabinoid receptor (CB1R) mediated inhibition of voltage-gated calcium channels (VGCCs). Numerous studies show, however, th

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______4612::d113b1811cf2911b911e71b79343fc1c
https://doi.org/10.1016/j.ceca.2009.07.007

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Dual modulation of CNS voltage-gated calcium channels by cannabinoids

Autor: Rogier Min, Natalia Lozovaya, Vera Tsintsadze, Nail Burnashev

Publikováno v: Lozovaya, N, Min, R, Tsintsadze, V & Burnashev, N 2009, ' Dual modulation of CNS voltage-gated calcium channels by cannabinoids : Focus on CB1 receptor-independent effects ', Cell Calcium, vol. 46, no. 3, pp. 154-62 . https://doi.org/10.1016/j.ceca.2009.07.007

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a047fba4024f530dea7dcf7b5b8388b7
https://hdl.handle.net/1871.1/f8cc7519-5e0e-46bd-aff3-da809c181557

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Evidence for a receptor-activated Ca2+ entry pathway independent from Ca2+ store depletion in endothelial cells

Autor: Nathalie C Girardin, Maud Frieden, Nicolas Demaurex, Wolfgang F. Graier, Roland Malli, Hélène Jousset

Publikováno v: Cell Calcium, Vol. 43, No 1 (2008) pp. 83-94

Ca(2+) entry in endothelial cells is a key signaling event as it prolongs the Ca(2+) signal activated by a receptor agonist, and thus allows an adequate production of a variety of compounds. The possible routes that lead to Ca(2+) entry in non-excita

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4a95f287a6e57a87779620807b28bbe8
https://doi.org/10.1016/j.ceca.2007.04.006

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Gain-of-function haplotype in the epithelial calcium channel TRPV6 is a risk factor for renal calcium stone formation

Autor: Andreas Pasch, Felix J. Frey, Olivier Bonny, Yoshiro Suzuki, Markus G. Mohaupt, Matthias A. Hediger

Publikováno v: Human molecular genetics
Human Molecular Genetics, vol. 17, no. 11, pp. 1613-1618
Suzuki, Yoshiro; Pasch, Andreas; Bonny, Olivier; Mohaupt, Markus G; Hediger, Matthias A; Frey, Felix J (2008). Gain-of-function haplotype in the epithelial calcium channel TRPV6 is a risk factor for renal calcium stone formation. Human molecular genetics, 17(11), pp. 1613-8. Oxford: Oxford University Press 10.1093/hmg/ddn048

The rate-limiting step of dietary calcium absorption in the intestine requires the brush border calcium entry channel TRPV6. The TRPV6 gene was completely sequenced in 170 renal calcium stone patients. The frequency of an ancestral TRPV6 haplotype co

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Quantification and Potential Functions of Endogenous Agonists of Transient Receptor Potential Channels in Patients With Irritable Bowel Syndrome

Autor: Corinne Rolland, Nicholas A. Veldhuis, Jessica Bertrand, Daniel P. Poole, Pauline Le Faouder, Nicolas Cenac, Nathalie Vergnolle, Lisa Zecchi, Tereza Bautzova, Vincenzo Stanghellini, Wolfgang Liedtke, Marc Dubourdeau, Justine Bertrand-Michel, Nigel W. Bunnett, Giovanni Barbara

Publikováno v: Gastroenterology, Vol. 149, No 2 (2015) pp. 433-44.e7

Background & Aims In mice, activation of the transient receptor potential cation channels (TRP) TRPV1, TRPV4, and TRPA1 causes visceral hypersensitivity. These receptors and their agonists might be involved in development of irritable bowel syndrome

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5af0ebef82cc860b51440105fd898509
https://archive-ouverte.unige.ch/unige:94521

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Feedback activation of phospholipase C via intracellular mobilization and store-operated influx of Ca2+ in insulin-secreting β-cells

Autor: Anders Tengholm, Oleg Dyachok, Erik Gylfe, Sophia Thore

Publikováno v: Journal of Cell Science. 118:4463-4471

Phospholipase C (PLC) regulates various cellular processes by catalyzing the formation of inositol-1,4,5-trisphosphate (IP3) and diacylglycerol from phosphatidylinositol-4,5-bisphosphate (PIP2). Here, we have investigated the influence of Ca2+ on rec

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fda52c1ed8967480a819c311204afb41
https://doi.org/10.1242/jcs.02577

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