Zobrazeno 1 - 10
of 48
pro vyhledávání: '"Calcitonin binding"'
Publikováno v:
Journal of Biological Chemistry. 279:1167-1175
The calcitonin receptor is a member of the class B family of G protein-coupled receptors, closely related to secretin and parathyroid hormone receptors. Although mechanisms of ligand binding have been directly explored for those receptors, current kn
Autor:
Carlo Gennari
Publikováno v:
Bone. 30:67-70
Bone pain is the most common symptom in osteoporotic patients. To date, there is mounting evidence that calcitonin significantly reduces bone pain in osteoporosis, and that the analgesic effect can be evident as soon as the second week of treatment.
Autor:
Ayumu Takehara, Qifeng Yang, Kennichi Kakudo, Misa Nakamura, Taro Gouda, Hiromoto Ohta, Masayasu Miyajima
Publikováno v:
Biochemical and Biophysical Research Communications. 284:1184-1188
C-cell tumors occur frequently (50%) in old WAG/Rij rats. Interestingly, genetically transmitted loss of CT binding sites in the kidney has also been demonstrated in WAG/Rij rats. To determine if these issues are resulted from mutation of calcitonin
Publikováno v:
Peptides. 20:361-366
Target organs for calcitonin gene related peptide were investigated in the abalone. To elucidate the function of this neuropeptide in the biomineralization process, we have localized, in different tissues from abalone, specific binding sites for huma
Publikováno v:
European Journal of Oral Sciences. 107:45-54
Osteoclasts are hematopoietic in origin and formed by proliferation, differentiation and fusion of osteoclast progenitor cells. However, the signal transducing mechanisms involved in generation of osteoclasts are not clear. We have used two well-know
Publikováno v:
Dental Traumatology. 12:272-276
Experimentally-induced external inflammatory tooth-root resorption can be inhibited by therapeutic doses of calcitonin. Such doses can be delivered by an intrinsically slow diffusion pathway, from a reservoir in endodontically-clebrided root canals,
Publikováno v:
Journal of Cancer Research and Clinical Oncology. 120:272-278
Saturable, specific, high-affinity calcitonin receptors were demonstrated in cultured neoplastic mononuclear spindle cells from a giant-cell tumor of the sacrum of a 38-year-old woman. The receptor was analyzed by autoradiography and125I-calcitonin b
Publikováno v:
The Journal of Comparative Neurology. 341:449-463
In this study we examined the distribution of calcitonin (CT) binding sites in the human medulla oblongata by in vitro autoradiography. In competition studies, the rank order of potency for calcitonins competing for 125I-salmon CT binding was salmon
Publikováno v:
Journal of Histochemistry & Cytochemistry. 39:1415-1420
We previously reported a simple method to detect osteoid matrices in decalcified bone sections by pre-treatment with cyanuric chloride. We have applied this technique to identify osteoclasts and their precursors in rats. In JB-4 sections prepared fro
Autor:
Bruce E. Kemp, Patrick M. Sexton, Jane M. Moseley, David M. Findlay, H G Schneider, F. A.O. Mendelsohn, C. S. D'santos, Thomas J. Martin
Publikováno v:
Scopus-Elsevier
In this study we have solubilized and characterized binding sites for calcitonin (CT) from sheep brainstem. Autoradiography of 125I-labelled salmon CT (125I-sCT) binding to sheep diencephalon revealed a similar pattern of binding to that seen in othe