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Convergent Synthesis of the NS5B Inhibitor GSK8175 Enabled by Transition Metal Catalysis.

Autor: Arrington K; API Chemistry , GlaxoSmithKline , King of Prussia , Pennsylvania 19406 , United States., Barcan GA; API Chemistry , GlaxoSmithKline , King of Prussia , Pennsylvania 19406 , United States., Calandra NA; API Chemistry , GlaxoSmithKline , King of Prussia , Pennsylvania 19406 , United States., Erickson GA; API Chemistry , GlaxoSmithKline , King of Prussia , Pennsylvania 19406 , United States., Li L; API Chemistry , GlaxoSmithKline , King of Prussia , Pennsylvania 19406 , United States., Liu L; API Chemistry , GlaxoSmithKline , King of Prussia , Pennsylvania 19406 , United States., Nilson MG; API Chemistry , GlaxoSmithKline , King of Prussia , Pennsylvania 19406 , United States., Strambeanu II; API Chemistry , GlaxoSmithKline , King of Prussia , Pennsylvania 19406 , United States., VanGelder KF; API Chemistry , GlaxoSmithKline , King of Prussia , Pennsylvania 19406 , United States., Woodard JL; API Chemistry , GlaxoSmithKline , King of Prussia , Pennsylvania 19406 , United States., Xie S; API Chemistry , GlaxoSmithKline , King of Prussia , Pennsylvania 19406 , United States., Allen CL; API Chemistry , GlaxoSmithKline , King of Prussia , Pennsylvania 19406 , United States., Kowalski JA; API Chemistry , GlaxoSmithKline , King of Prussia , Pennsylvania 19406 , United States., Leitch DC; API Chemistry , GlaxoSmithKline , King of Prussia , Pennsylvania 19406 , United States.

Publikováno v: The Journal of organic chemistry [J Org Chem] 2019 Apr 19; Vol. 84 (8), pp. 4680-4694. Date of Electronic Publication: 2018 Oct 29.

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Akademický článek

Development of enantioselective synthetic routes to the hasubanan and acutumine alkaloids.

Autor: Calandra NA; Department of Chemistry, Yale University , New Haven, Connecticut 06520, United States., King SM, Herzon SB

Publikováno v: The Journal of organic chemistry [J Org Chem] 2013 Oct 18; Vol. 78 (20), pp. 10031-57. Date of Electronic Publication: 2013 Sep 27.

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Akademický článek

Total syntheses of (-)-acutumine and (-)-dechloroacutumine.

Autor: King SM; Department of Chemistry, Yale University, 225 Prospect Street, New Haven, CT 06520-8107, USA., Calandra NA, Herzon SB

Publikováno v: Angewandte Chemie (International ed. in English) [Angew Chem Int Ed Engl] 2013 Mar 25; Vol. 52 (13), pp. 3642-5. Date of Electronic Publication: 2013 Feb 20.

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Efficient entry to the hasubanan alkaloids: first enantioselective total syntheses of (-)-hasubanonine, (-)-runanine, (-)-delavayine, and (+)-periglaucine B.

Autor: Herzon SB; Department of Chemistry, Yale University, 225 Prospect Street, New Haven, CT, 06520-8107, USA. seth.herzon@yale.edu, Calandra NA, King SM

Publikováno v: Angewandte Chemie (International ed. in English) [Angew Chem Int Ed Engl] 2011 Sep 12; Vol. 50 (38), pp. 8863-6. Date of Electronic Publication: 2011 Jun 03.

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Akademický článek

Total synthesis of Spiruchostatin A via chemoselective macrocyclization using an accessible enantiomerically pure latent thioester.

Autor: Calandra NA; Department of Chemistry, Hobart College, Geneva, New York 14456, USA., Cheng YL, Kocak KA, Miller JS

Publikováno v: Organic letters [Org Lett] 2009 May 07; Vol. 11 (9), pp. 1971-4.

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