Zobrazeno 1 - 10
of 45
pro vyhledávání: '"Calado DP"'
Autor:
Barbosa, RR, Xu, AQ, D’Andrea, D, Copley, F, Patel, H, Chakravarty, P, Clear, A, Calaminici, M, Janz, M, Zhang, B, Schmidt-Supprian, M, Wang, J, Gribben, JG, Tooze, R, Fitzgibbon, J, Franzoso, G, Rajewsky, K, Calado, DP
NF-κB and MYC are found co-deregulated in human B and plasma-cell cancers. In physiology, NF-κB is necessary for terminal B-to-plasma cell differentiation, whereas MYC repression is required. It is thus unclear if NF-κB/MYC co-deregulation is deve
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od______1032::6e34f141fe72f56ed17233373d92e4b2
http://hdl.handle.net/10044/1/99736
http://hdl.handle.net/10044/1/99736
Plasma cells produce antibodies that are essential for protection from infection and for vaccination success. Plasma cells are also at the origin of currently incurable hematological malignancies, most notably multiple myeloma. However, the study of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=sharebioRxiv::bc5d4871b18491ad5d23295bd60bc66f
Autor:
Calado DP, Sasaki Y, Godinho SA, Pellerin A, Kxf6chert K, Sleckman BP, de Alboran IM, Janz M, Rodig S, Rajewsky K.
Publikováno v:
Natural Immunology.
Autor:
Sander S, Calado DP, Srinivasan L, Kxf6chert K, Zhang B, Rosolowski M, Rodig SJ, Holzmann K, Stilgenbauer S, Siebert R, Bullinger L, Rajewsky K.
Publikováno v:
Cancer Cell.
Somatic hypermutation of immunoglobulin variable region (IgV) genes and affinity maturation of the antibody response are the hallmarks of the germinal center (GC) reaction in T cell-dependent immune responses. Determining the consequences of the expe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=core_ac_uk__::1c6afcff1df9f94e371b28724ac53010
Autor:
Zhang L; Immunity and Cancer, Francis Crick Institute, London, UK., Toboso-Navasa A; Immunity and Cancer, Francis Crick Institute, London, UK., Gunawan A; Immunity and Cancer, Francis Crick Institute, London, UK., Camara A; Immunity and Cancer, Francis Crick Institute, London, UK., Nakagawa R; Immunity and Cancer, Francis Crick Institute, London, UK., Finsterbusch K; Immunoregulation, Francis Crick Institute, London, UK., Chakravarty P; Bioinformatics and Biostatistics, Francis Crick Institute, London, UK., Newman R; Immune Receptor Activation Laboratory, Francis Crick Institute, London, UK., Zhang Y; Institute of Immunology and Immunotherapy, University of Birmingham, Birmingham, UK., Eilers M; Theodor Boveri Institute and Comprehensive Cancer Center Mainfranken, Biocenter, University of Würzburg, Würzburg, Germany., Wack A; Immunoregulation, Francis Crick Institute, London, UK., Tolar P; Immune Receptor Activation Laboratory, Francis Crick Institute, London, UK.; Division of Infection and Immunity, Institute of Immunity and Transplantation, University College London, London, UK., Toellner KM; Institute of Immunology and Immunotherapy, University of Birmingham, Birmingham, UK., Calado DP; Immunity and Cancer, Francis Crick Institute, London, UK.
Publikováno v:
Science immunology [Sci Immunol] 2024 Apr 05; Vol. 9 (94), pp. eadk0092. Date of Electronic Publication: 2024 Apr 05.
Autor:
D'Avola A, Legrave N, Tajan M, Chakravarty P, Shearer RL, King HW, Kluckova K, Cheung EC, Clear AJ, Gunawan AS, Zhang L, James LK, MacRae JI, Gribben JG, Calado DP, Vousden KH, Riches JC
Publikováno v:
The Journal of clinical investigation [J Clin Invest] 2024 Feb 15; Vol. 134 (4). Date of Electronic Publication: 2024 Feb 15.
Autor:
Nakagawa R, Llorian M, Varsani-Brown S, Chakravarty P, Camarillo JM, Barry D, George R, Blackledge NP, Duddy G, Kelleher NL, Klose RJ, Turner M, Calado DP
Publikováno v:
BioRxiv : the preprint server for biology [bioRxiv] 2023 Oct 31. Date of Electronic Publication: 2023 Oct 31.
Autor:
Griger J; Institute of Molecular Oncology and Functional Genomics, School of Medicine, Technische Universität München, 81675 Munich, Germany; Center for Translational Cancer Research (TranslaTUM), School of Medicine, Technische Universität München, 81675 Munich, Germany; German Cancer Consortium (DKTK), Heidelberg 69120, Germany., Widholz SA; Institute of Molecular Oncology and Functional Genomics, School of Medicine, Technische Universität München, 81675 Munich, Germany; Center for Translational Cancer Research (TranslaTUM), School of Medicine, Technische Universität München, 81675 Munich, Germany; German Cancer Consortium (DKTK), Heidelberg 69120, Germany., Jesinghaus M; Institute of Pathology, School of Medicine, Technische Universität München, Munich 81675, Germany; Institute of Pathology, Philipps University Marburg and University Hospital Marburg (UKGM), Marburg, Germany; Institute for Experimental Cancer Therapy, School of Medicine, Technische Universität München, 81675 Munich, Germany., de Andrade Krätzig N; Institute of Molecular Oncology and Functional Genomics, School of Medicine, Technische Universität München, 81675 Munich, Germany; Center for Translational Cancer Research (TranslaTUM), School of Medicine, Technische Universität München, 81675 Munich, Germany; German Cancer Consortium (DKTK), Heidelberg 69120, Germany., Lange S; Institute of Molecular Oncology and Functional Genomics, School of Medicine, Technische Universität München, 81675 Munich, Germany; Center for Translational Cancer Research (TranslaTUM), School of Medicine, Technische Universität München, 81675 Munich, Germany; Department of Medicine II, Klinikum rechts der Isar, School of Medicine, Technische Universität München, 81675 Munich, Germany., Engleitner T; Institute of Molecular Oncology and Functional Genomics, School of Medicine, Technische Universität München, 81675 Munich, Germany; Center for Translational Cancer Research (TranslaTUM), School of Medicine, Technische Universität München, 81675 Munich, Germany., Montero JJ; Institute of Molecular Oncology and Functional Genomics, School of Medicine, Technische Universität München, 81675 Munich, Germany; Center for Translational Cancer Research (TranslaTUM), School of Medicine, Technische Universität München, 81675 Munich, Germany., Zhigalova E; Institute of Molecular Oncology and Functional Genomics, School of Medicine, Technische Universität München, 81675 Munich, Germany; Center for Translational Cancer Research (TranslaTUM), School of Medicine, Technische Universität München, 81675 Munich, Germany., Öllinger R; Institute of Molecular Oncology and Functional Genomics, School of Medicine, Technische Universität München, 81675 Munich, Germany; Center for Translational Cancer Research (TranslaTUM), School of Medicine, Technische Universität München, 81675 Munich, Germany., Suresh V; Institute of Molecular Oncology and Functional Genomics, School of Medicine, Technische Universität München, 81675 Munich, Germany; Center for Translational Cancer Research (TranslaTUM), School of Medicine, Technische Universität München, 81675 Munich, Germany., Winkler W; Immune Regulation and Cancer, Max-Delbrück-Center for Molecular Medicine in the Helmholtz Association, Berlin 13125, Germany., Lier S; Department of Medicine II, Klinikum rechts der Isar, School of Medicine, Technische Universität München, 81675 Munich, Germany., Baranov O; Institute of Molecular Oncology and Functional Genomics, School of Medicine, Technische Universität München, 81675 Munich, Germany; Center for Translational Cancer Research (TranslaTUM), School of Medicine, Technische Universität München, 81675 Munich, Germany., Trozzo R; Institute of Molecular Oncology and Functional Genomics, School of Medicine, Technische Universität München, 81675 Munich, Germany., Ben Khaled N; Institute of Molecular Oncology and Functional Genomics, School of Medicine, Technische Universität München, 81675 Munich, Germany; German Cancer Consortium (DKTK), Heidelberg 69120, Germany; Department of Medicine II, University Hospital, LMU Munich, 81377 Munich, Germany., Chakraborty S; Institute of Pathology, School of Medicine, Technische Universität München, Munich 81675, Germany., Yu J; Center for Translational Cancer Research (TranslaTUM), School of Medicine, Technische Universität München, 81675 Munich, Germany., Konukiewitz B; Institute of Pathology, School of Medicine, Technische Universität München, Munich 81675, Germany; Institute of Pathology, Universitätsklinikum Schleswig-Holstein Campus Kiel, Kiel 24105, Germany., Steiger K; Institute of Pathology, School of Medicine, Technische Universität München, Munich 81675, Germany., Pfarr N; Institute of Pathology, School of Medicine, Technische Universität München, Munich 81675, Germany., Rajput A; Institute of Molecular Oncology and Functional Genomics, School of Medicine, Technische Universität München, 81675 Munich, Germany; Center for Translational Cancer Research (TranslaTUM), School of Medicine, Technische Universität München, 81675 Munich, Germany., Sailer D; Institute of Molecular Oncology and Functional Genomics, School of Medicine, Technische Universität München, 81675 Munich, Germany; Center for Translational Cancer Research (TranslaTUM), School of Medicine, Technische Universität München, 81675 Munich, Germany; German Cancer Consortium (DKTK), Heidelberg 69120, Germany., Keller G; Institute of Pathology, School of Medicine, Technische Universität München, Munich 81675, Germany., Schirmacher P; Institute of Pathology, Universitätsklinikum Heidelberg, Heidelberg 69120, Germany., Röcken C; Institute of Pathology, Universitätsklinikum Schleswig-Holstein Campus Kiel, Kiel 24105, Germany., Fagerstedt KW; Department of Pathology, University of Helsinki, Helsinki, Finland., Mayerle J; German Cancer Consortium (DKTK), Heidelberg 69120, Germany; Department of Medicine II, University Hospital, LMU Munich, 81377 Munich, Germany., Schmidt-Supprian M; Institute of Molecular Oncology and Functional Genomics, School of Medicine, Technische Universität München, 81675 Munich, Germany; German Cancer Consortium (DKTK), Heidelberg 69120, Germany; Institute of Experimental Hematology, School of Medicine, Technical University of Munich, Munich 81675, Germany., Schneider G; Department of Medicine II, Klinikum rechts der Isar, School of Medicine, Technische Universität München, 81675 Munich, Germany; Department of General, Visceral and Pediatric Surgery, University Medical Center Göttingen, 37075 Göttingen, Germany., Weichert W; Institute of Pathology, School of Medicine, Technische Universität München, Munich 81675, Germany., Calado DP; Immune Regulation and Cancer, Max-Delbrück-Center for Molecular Medicine in the Helmholtz Association, Berlin 13125, Germany; Immunity and Cancer, Francis Crick Institute, NW1 1AT London, UK., Sommermann T; Immune Regulation and Cancer, Max-Delbrück-Center for Molecular Medicine in the Helmholtz Association, Berlin 13125, Germany., Klöppel G; Institute of Pathology, School of Medicine, Technische Universität München, Munich 81675, Germany., Rajewsky K; Immune Regulation and Cancer, Max-Delbrück-Center for Molecular Medicine in the Helmholtz Association, Berlin 13125, Germany., Saur D; Center for Translational Cancer Research (TranslaTUM), School of Medicine, Technische Universität München, 81675 Munich, Germany; German Cancer Consortium (DKTK), Heidelberg 69120, Germany; Department of Medicine II, Klinikum rechts der Isar, School of Medicine, Technische Universität München, 81675 Munich, Germany; Institute for Experimental Cancer Therapy, School of Medicine, Technische Universität München, 81675 Munich, Germany., Rad R; Institute of Molecular Oncology and Functional Genomics, School of Medicine, Technische Universität München, 81675 Munich, Germany; Center for Translational Cancer Research (TranslaTUM), School of Medicine, Technische Universität München, 81675 Munich, Germany; German Cancer Consortium (DKTK), Heidelberg 69120, Germany; Department of Medicine II, Klinikum rechts der Isar, School of Medicine, Technische Universität München, 81675 Munich, Germany. Electronic address: roland.rad@tum.de.
Publikováno v:
Cancer cell [Cancer Cell] 2023 Jul 10; Vol. 41 (7), pp. 1327-1344.e10. Date of Electronic Publication: 2023 Jun 22.
Autor:
Apollonio B; School of Cancer and Pharmaceutical Sciences, Faculty of Life Sciences & Medicine, King's College London, London, United Kingdom., Spada F; BRC Advanced Cytometry Platform and., Petrov N; BRC Advanced Cytometry Platform and., Cozzetto D; BRC Translational Bioinformatics at Guy's and St. Thomas's NHS Foundation Trust and King's College London, London, United Kingdom.; Division of Digestive Diseases, Faculty of Medicine, Imperial College London, London, United Kingdom., Papazoglou D; School of Cancer and Pharmaceutical Sciences, Faculty of Life Sciences & Medicine, King's College London, London, United Kingdom., Jarvis P; 5th Surgical Department, Aristotle University of Thessaloniki, Thessaloniki, Greece., Kannambath S; BRC Genomics Research Platform at Guy's and St. Thomas's NHS Foundation Trust and King's College London, London, United Kingdom., Terranova-Barberio M; BRC Advanced Cytometry Platform and., Amini RM; Department of Immunology, Genetics and Pathology, Uppsala University and Hospital, Uppsala, Sweden., Enblad G; Department of Immunology, Genetics and Pathology, Uppsala University and Hospital, Uppsala, Sweden., Graham C; School of Cancer and Pharmaceutical Sciences, Faculty of Life Sciences & Medicine, King's College London, London, United Kingdom., Benjamin R; School of Cancer and Pharmaceutical Sciences, Faculty of Life Sciences & Medicine, King's College London, London, United Kingdom., Phillips E; School of Cancer and Pharmaceutical Sciences, Faculty of Life Sciences & Medicine, King's College London, London, United Kingdom., Ellis R; BRC Advanced Cytometry Platform and., Nuamah R; BRC Genomics Research Platform at Guy's and St. Thomas's NHS Foundation Trust and King's College London, London, United Kingdom., Saqi M; BRC Translational Bioinformatics at Guy's and St. Thomas's NHS Foundation Trust and King's College London, London, United Kingdom., Calado DP; Immunity & Cancer Laboratory, Francis Crick Institute, London, United Kingdom., Rosenquist R; Department of Molecular Medicine and Surgery, Karolinska Institutet, Stockholm, Sweden., Sutton LA; Department of Molecular Medicine and Surgery, Karolinska Institutet, Stockholm, Sweden., Salisbury J; Department of Haematology, King's College Hospital NHS Foundation Trust, London, United Kingdom., Zacharioudakis G; 5th Surgical Department, Aristotle University of Thessaloniki, Thessaloniki, Greece., Vardi A; Hematology Department and HCT Unit, G. Papanikolaou Hospital, Thessaloniki, Greece., Hagner PR; Bristol-Myers Squibb, Summit, New Jersey, USA., Gandhi AK; Bristol-Myers Squibb, Summit, New Jersey, USA., Bacac M; Roche Innovation Center Zurich, Schlieren, Switzerland., Claus C; Roche Innovation Center Zurich, Schlieren, Switzerland., Umana P; Roche Innovation Center Zurich, Schlieren, Switzerland., Jarrett RF; MRC-University of Glasgow Centre for Virus Research, Glasgow, United Kingdom., Klein C; Roche Innovation Center Zurich, Schlieren, Switzerland., Deutsch A; Division of Hematology, Medical University of Graz, Graz, Austria., Ramsay AG; School of Cancer and Pharmaceutical Sciences, Faculty of Life Sciences & Medicine, King's College London, London, United Kingdom.
Publikováno v:
The Journal of clinical investigation [J Clin Invest] 2023 Jul 03; Vol. 133 (13). Date of Electronic Publication: 2023 Jul 03.