Ex vivo study of molecular changes of stained teeth following hydrogen peroxide and peroxymonosulfate treatments

Autor: Paulo Wender P. Gomes, Simone Zuffa, Anelize Bauermeister, Andrés Mauricio Caraballo-Rodríguez, Haoqi Nina Zhao, Helena Mannochio-Russo, Cajetan Dogo-isonagie, Om Patel, Paloma Pimenta, Jennifer Gronlund, Stacey Lavender, Shira Pilch, Venda Maloney, Michael North, Pieter C. Dorrestein

Publikováno v: Scientific Reports, Vol 13, Iss 1, Pp 1-10 (2023)

Abstract White teeth can give confidence and tend to be associated with a healthier lifestyle in modern society. Therefore, tooth-bleaching strategies have been developed, including the use of hydrogen peroxide. Recently, peroxymonosulfate has been i

Externí odkaz: https://doaj.org/article/e7d6c72c24784765b6d788446f131796

The effects of bleaching strategies on the teeth metabolome

Autor: Paulo Wender Portal Gomes, Simone Zuffa, Anelize Baumeister, Andrés Mauricio Caraballo-Rodríguez, Haoqi Nina Zhao, Helena Mannochio-Russo, Michael North, Cajetan Dogo-isonagie, Om Patel, Stacey Lavender, Paloma Pimenta, Jennifer Gronlund, Shira Pilch, Venda Maloney, Pieter C. Dorrestein

White teeth can give confidence and tend to be associated with a healthier lifestyle in modern society. Therefore, modern tooth bleaching strategies have been developed, including the use of hydrogen peroxide and peroxymonosulfate. Although both mole

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::f965bb8353850c36e137ed85a24a957d
https://doi.org/10.21203/rs.3.rs-2861171/v1

Design and synthesis of small molecule-sulfotyrosine mimetics that inhibit HIV-1 entry

Autor: Katheryn Lohith, Cajetan Dogo-Isonagie, Robert D. O’Connor, Carole A. Bewley, Sivakoteswara Rao Mandadapu, Hong-Bing Liu, Su Lin Lee, Sabrina Lusvarghi

Publikováno v: Bioorg Med Chem

In the absence of a cure or vaccine for HIV/AIDS, small molecule inhibitors remain an attractive choice for antiviral therapeutics. Recent structural and functional studies of the HIV-1 surface envelope glycoprotein gp120 have revealed sites of vulne

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7d943e3213fc68b60d069d611283f962
https://pubmed.ncbi.nlm.nih.gov/26968647

Structure-Based Identification and Neutralization Mechanism of Tyrosine Sulfate Mimetics That Inhibit HIV-1 Entry

Autor: Jeremy R. Greenwood, George J. Leslie, Mark K. Louder, Carole A. Bewley, Leah L. Frye, Timothy S. Luongo, Cajetan Dogo-Isonagie, Priyamvada Acharya, Loïc Martin, Son N. Lam, K. Shawn Watts, Asim K. Debnath, Peter D. Kwong, John R. Mascola, Judith M. LaLonde, James A. Hoxie

Publikováno v: ACS Chemical Biology
ACS Chemical Biology, 2011, 6 (10), pp.1069-1077. ⟨10.1021/cb200068b⟩
ACS Chemical Biology, American Chemical Society, 2011, 6 (10), pp.1069-1077. ⟨10.1021/cb200068b⟩

Tyrosine sulfate-mediated interactions play an important role in HIV-1 entry. After engaging the CD4 receptor at the cell surface, the HIV-1 gp120 glycoprotein binds to the CCR5 co-receptor via an interaction that requires two tyrosine sulfates, at p

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cc29b1c9fa6a5642d1e30ec0f27bd325
https://doi.org/10.1021/cb200068b

Scalable Methodology for the Catalytic, Asymmetric α-Bromination of Acid Chlorides

Autor: Cajetan Dogo-Isonagie, Tefsit Bekele, Stefan France, Jamison Wolfer, Anthony Weatherwax, Andrew E. Taggi, Thomas Lectka

Publikováno v: The Journal of Organic Chemistry. 71:8946-8949

The optimization of a practical, catalytic, asymmetric process for the alpha-bromination of acid chlorides to produce synthetically versatile, optically active alpha-bromoesters is reported. A range of products is produced in high enantioselectivity

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7e9b6f835b1dc7378df673c0435c2b7d
https://doi.org/10.1021/jo061522l