Zobrazeno 1 - 10
of 59
pro vyhledávání: '"Caiyun G. Li"'
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 14, p 11432 (2023)
Renal cell carcinoma (RCC) is the most common form of kidney cancer, consisting of multiple distinct subtypes. RCC has the highest mortality rate amongst the urogenital cancers, with kidney renal clear cell carcinoma (KIRC), kidney renal papillary ce
Externí odkaz:
https://doaj.org/article/dcba54cc58c742668963bc9ac727b34b
Autor:
Eui Jung Moon, Stephano S. Mello, Caiyun G. Li, Jen-Tsan Chi, Kaushik Thakkar, Jacob G. Kirkland, Edward L. Lagory, Ik Jae Lee, Anh N. Diep, Yu Miao, Marjan Rafat, Marta Vilalta, Laura Castellini, Adam J. Krieg, Edward E. Graves, Laura D. Attardi, Amato J. Giaccia
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-18 (2021)
Hypoxia plays a critical role in tumor progression including invasion and metastasis. Here, the authors screened several hypoxia inducible genes and identified the oncogenic role of MAFF in breast cancer metastasis and that it activates IL11/STAT3 pa
Externí odkaz:
https://doaj.org/article/74a0bdf041f848a69bf653962a2ec1b4
Autor:
Chun-Lung Chiu, Caiyun G. Li, Erik Verschueren, Ru M. Wen, Dalin Zhang, Catherine A. Gordon, Hongjuan Zhao, Amato J. Giaccia, James D. Brooks
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 7, p 6258 (2023)
Increased expression of NUSAP1 has been identified as a robust prognostic biomarker in prostate cancer and other malignancies. We have previously shown that NUSAP1 is positively regulated by E2F1 and promotes cancer invasion and metastasis. To furthe
Externí odkaz:
https://doaj.org/article/8b7f9b45b212493299a7a5dfc6081550
Autor:
Debopam Ghosh, Tho D. Pham, Padma P. Nanaware, Deepanwita Sengupta, Lital N. Adler, Caiyun G. Li, Xiao He, Mary E. O'Mara, Aaron B. Kantor, Khoa D. Nguyen, Yang Yang, Laurence C. Eisenlohr, Peter E. Jensen, Leonore A. Herzenberg, Lawrence J. Stern, Scott D. Boyd, Eliver E.B. Ghosn, Elizabeth D. Mellins
Publikováno v:
Cell Reports, Vol 38, Iss 4, Pp 110200- (2022)
Summary: The non-classical Major Histocompatibility Complex class II (MHCII) protein, H2-M, edits peptides bound to conventional MHCII in favor of stable peptide/MHCII (p/MHCII) complexes. Here, we show that H2-M deficiency affects B-1 cell survival,
Externí odkaz:
https://doaj.org/article/bd96043bdd1c4fd6babe806d58bfbeb0
Autor:
Lingli Wang, Jan-Renier Moonen, Aiqin Cao, Sarasa Isobe, Caiyun G. Li, Nancy F. Tojais, Shalina Taylor, David P. Marciano, Pin-I. Chen, Mingxia Gu, Dan Li, Rebecca L. Harper, Nesrine El-Bizri, Yu-Mee Kim, Kryn Stankunas, Marlene Rabinovitch
Publikováno v:
Circulation Research. 132:545-564
Objective: Mutations in BMPR2 (bone morphogenetic protein receptor 2) are associated with familial and sporadic pulmonary arterial hypertension (PAH). The functional and molecular link between loss of BMPR2 in pulmonary artery smooth muscle cells (PA
Autor:
Amato J. Giaccia, Quynh-Thu Le, Daniel T. Chang, Monica M. Olcina, Caiyun G. Li, Michael S. Binkley, Deana Colburg, Rie von Eyben, Vignesh Viswanathan, Dhanya K. Nambiar, Quaovi H. Sodji
Proportion of various immune cell type in TME of pancreatic cancer (TGCA).
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7f87d4a67ddafdc13b93189ab0a2ffb7
https://doi.org/10.1158/2767-9764.22545558
https://doi.org/10.1158/2767-9764.22545558
Autor:
Amato J. Giaccia, Quynh-Thu Le, Daniel T. Chang, Monica M. Olcina, Caiyun G. Li, Michael S. Binkley, Deana Colburg, Rie von Eyben, Vignesh Viswanathan, Dhanya K. Nambiar, Quaovi H. Sodji
Supplementary Figure S1: Proportion of total NK cell in the tumor microenvironment of 138 pancreatic cancer patients based on the CIBERSORTx analysis of TCGA. Supplementary Figure S2: Immunohistochemical staining of NK cells (Red circle) using NKp46.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ba9ce888105d74ea970ff4d26bf0cc22
https://doi.org/10.1158/2767-9764.22545561.v1
https://doi.org/10.1158/2767-9764.22545561.v1
Autor:
Amato J. Giaccia, Edward E. Graves, Quaovi H. Sodji, Yu Xu, Caiyun G. Li, Saravanan Nandagopal
Supplementary figures and legends S1-S8
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::09d56d5336fe13598a78f19d39034fa9
https://doi.org/10.1158/2326-6066.22544337
https://doi.org/10.1158/2326-6066.22544337
Autor:
Amato J. Giaccia, Edward E. Graves, Quaovi H. Sodji, Yu Xu, Caiyun G. Li, Saravanan Nandagopal
Many solid tumors have low levels of cytotoxic CD56dim natural killer (NK) cells, suggesting that CD56dim NK-cell exclusion from the tumor microenvironment (TME) contributes to the decreased response rate of immunotherapy. Complement component 3a (C3
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aed99cd4e11eff4c38a3bffcb5d44b6e
https://doi.org/10.1158/2326-6066.c.6550611.v1
https://doi.org/10.1158/2326-6066.c.6550611.v1