Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Caiyue Xu"'
Autor:
Alexander Huang, Claire Friedman, Yuki Muroyama, Sasikanth Manne, Divij Mathew, Lakshmi Chilukuri, Allison Greenplate, Ramin Herati, E John Wherry, Derek Oldridge, Caiyue Xu, Dimitriy Zamarin
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 9, Iss Suppl 2 (2021)
Externí odkaz:
https://doaj.org/article/3f203e3ea9b9452d9a2d89f741721d5e
Autor:
Shuangying Jiang, Yan Liu, Caiyue Xu, Yun Wang, Jianhui Gong, Yue Shen, Qingyu Wu, Jef D. Boeke, Junbiao Dai
Publikováno v:
G3: Genes, Genomes, Genetics, Vol 7, Iss 12, Pp 3857-3866 (2017)
Using a comprehensive library of histone H2A and H2B mutants, we assessed the biological function of each amino acid residue involved in various stress conditions including exposure to different DNA damage-inducing reagents, different growth temperat
Externí odkaz:
https://doaj.org/article/9b93a751e2e8436c81df0da79af1f8ed
Autor:
Lu Wang, Gregory Donahue, Chen Zhang, Aaron Havas, Xue Lei, Caiyue Xu, Wenliang Wang, Golnaz Vahedi, Peter D. Adams, Shelley L. Berger
Publikováno v:
bioRxiv
SummaryGene expression programs are regulated by enhancers which act in a context-specific manner, and can reside at great distances from their target genes. Extensive three-dimensional (3D) genome reorganization occurs in senescence, but how enhance
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ce22ee9f9e9f64e694363b307ab6c916
https://doi.org/10.1101/2023.05.22.541769
https://doi.org/10.1101/2023.05.22.541769
Publikováno v:
Environment, Development and Sustainability.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6a66b28fb858cdf8ec808b775a7fae09
https://doi.org/10.1007/s10668-023-02935-5
https://doi.org/10.1007/s10668-023-02935-5
Autor:
Parinaz Fozouni, Vemika Chandra, Congcong Lu, Lu Wang, Jing Jiang, Caiyue Xu, Corey Bretz, Melanie Ott, Terje Johansen, Peter D. Adams, Jeffrey D. Winkler, Ravi K. Amaravadi, Shelley L. Berger, Gry Evjen, Michael C. Nicastri, Zhixun Dou, Wei Tong, Benjamin A. Garcia
Publikováno v:
Nature cell biology, vol 22, iss 10
Nature cell biology
Nature cell biology
SIRT1 (Sir2) is an NAD+-dependent deacetylase that plays critical roles in a broad range of biological events, including metabolism, the immune response and ageing1,2,3,4,5. Although there is strong interest in stimulating SIRT1 catalytic activity, t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ad2cf4446e5fa5dd1ffb2a316b8adb87
https://doi.org/10.1038/s41556-020-00579-5
https://doi.org/10.1038/s41556-020-00579-5
Autor:
Jae-Hyun Yang, Motoshi Hayano, Patrick T. Griffin, João A. Amorim, Michael S. Bonkowski, John K. Apostolides, Elias L. Salfati, Marco Blanchette, Elizabeth M. Munding, Mital Bhakta, Yap Ching Chew, Wei Guo, Xiaojing Yang, Sun Maybury-Lewis, Xiao Tian, Jaime M. Ross, Giuseppe Coppotelli, Margarita V. Meer, Ryan Rogers-Hammond, Daniel L. Vera, Yuancheng Ryan Lu, Jeffrey W. Pippin, Michael L. Creswell, Zhixun Dou, Caiyue Xu, Sarah J. Mitchell, Abhirup Das, Brendan L. O’Connell, Sachin Thakur, Alice E. Kane, Qiao Su, Yasuaki Mohri, Emi K. Nishimura, Laura Schaevitz, Neha Garg, Ana-Maria Balta, Meghan A. Rego, Meredith Gregory-Ksander, Tatjana C. Jakobs, Lei Zhong, Hiroko Wakimoto, Jihad El Andari, Dirk Grimm, Raul Mostoslavsky, Amy J. Wagers, Kazuo Tsubota, Stephen J. Bonasera, Carlos M. Palmeira, Jonathan G. Seidman, Christine E. Seidman, Norman S. Wolf, Jill A. Kreiling, John M. Sedivy, George F. Murphy, Richard E. Green, Benjamin A. Garcia, Shelley L. Berger, Philipp Oberdoerffer, Stuart J. Shankland, Vadim N. Gladyshev, Bruce R. Ksander, Andreas R. Pfenning, Luis A. Rajman, David A. Sinclair
Publikováno v:
Cell. 186:305-326.e27
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a40d556fd25f6db5d4a9f1a0234305aa
https://doi.org/10.1016/j.cell.2022.12.027
https://doi.org/10.1016/j.cell.2022.12.027
Autor:
Yuki Muroyama, Sasikanth Manne, Derek A. Oldridge, Nils Wellhausen, Allison R. Greenplate, Lakshmi Chilukuri, Divij Mathew, Caiyue Xu, Ramin S. Herati, Alexander C. Huang, Dmitriy Zamarin, Claire F. Friedman, E. John Wherry
Publikováno v:
Cancer Research. 82:3579-3579
Despite the high tumor mutational burden (TMB), immune check point blockade (ICB) still fails in about half of microsatellite instability-high (MSI-H) cancer patients, suggesting underlying immune dysregulation. Immune profiling of peripheral blood f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c53c34fadbfde34a2d97c00a80991b03
https://doi.org/10.1158/1538-7445.am2022-3579
https://doi.org/10.1158/1538-7445.am2022-3579
Autor:
Brendan O'Connell, Xiaojing Yang, Jaime M. Ross, Yuancheng Lu, Jonathan G. Seidman, Mital Bhakta, Amy J. Wagers, João A. Amorim, Qiao Su, Bruce R. Ksander, Jae-Hyun Yang, Jill A. Kreiling, Elias L. Salfati, Stuart J. Shankland, Richard E. Green, Christine E. Seidman, Ana-Maria Balta, Andreas R. Pfenning, George F. Murphy, Michael Bonkowski, Benjamin A. Garcia, Luis A. Rajman, Patrick Griffin, Marco Blanchette, Yasuaki Mohri, Meghan A. Rego, Sarah J. Mitchell, Meredith S Gregory-Ksander, Kazuo Tsubota, Sachin Thakur, Raul Mostoslavsky, Caiyue Xu, Hiroko Wakimoto, John M. Sedivy, Norman S. Wolf, Philipp Oberdoerffer, Yap Ching Chew, John K. Apostolides, Alice E. Kane, Michael L. Creswell, Laura Schaevitz, Motoshi Hayano, Zhixun Dou, Margarita V. Meer, Giuseppe Coppotelli, Elizabeth M. Munding, Xiao Tian, Carlos M. Palmeira, Wei Guo, Shelley L. Berger, Tatjana C. Jakobs, Daniel L. Vera, Emi K. Nishimura, Lei Zhong, David A. Sinclair, Abhirup Das, Jeffrey W. Pippin, Vadim N. Gladyshev, Stephen J. Bonasera, Neha Garg
Publikováno v:
SSRN Electronic Journal.
All living things experience entropy, manifested as a loss of inherited genetic and epigenetic information over time. In yeast, epigenetic changes result in a loss of cell identity and sterility, both hallmarks of yeast aging. In mammals, epigenetic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::245f07f1a3ddd3b145824aa1a6d8802f
https://doi.org/10.2139/ssrn.3951490
https://doi.org/10.2139/ssrn.3951490
Publikováno v:
Autophagy
Macroautophagic/autophagic degradation of nuclear components (or nuclear autophagy) is a poorly understood area in autophagy research. We previously reported the nuclear lamina protein LMNB1 (lamin B1) as a nuclear autophagy substrate in primary huma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::03b37926bc9b9f42c2f62a0c111d25f4
https://hdl.handle.net/10037/29282
https://hdl.handle.net/10037/29282
Autor:
Ramin S. Herati, Claire F. Friedman, Divij Mathew, Yuki Muroyama, Caiyue Xu, Alexander C. Huang, Allison R. Greenplate, E. John Wherry, D. Zamarin, Lakshmi Chilukuri, Derek A. Oldridge, Sasikanth Manne
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 9, Iss Suppl 2 (2021)
BackgroundDespite the success of immune checkpoint blockade (ICB), many patients still fail to achieve durable clinical benefit. Previous studies have shown that CD8 T cells are reinvigorated by ICB. However, not all patients with this immunological
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::03ee49309dbcc306fde13b632ae94d7a
https://doi.org/10.1136/jitc-2021-sitc2021.310
https://doi.org/10.1136/jitc-2021-sitc2021.310