Zobrazeno 1 - 10
of 75
pro vyhledávání: '"Caiying Guo"'
Autor:
P. Dylan Rich, Stephan Yves Thiberge, Benjamin B. Scott, Caiying Guo, D. Gowanlock R. Tervo, Carlos D. Brody, Alla Y. Karpova, Nathaniel D. Daw, David W. Tank
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-13 (2024)
Abstract The precise neural mechanisms within the brain that contribute to the remarkable lifetime persistence of memory are not fully understood. Two-photon calcium imaging allows the activity of individual cells to be followed across long periods,
Externí odkaz:
https://doaj.org/article/d3f4113102e34dc08850517228dca327
Autor:
Nuo Li, Susu Chen, Zengcai V Guo, Han Chen, Yan Huo, Hidehiko K Inagaki, Guang Chen, Courtney Davis, David Hansel, Caiying Guo, Karel Svoboda
Publikováno v:
eLife, Vol 8 (2019)
Optogenetics allows manipulations of genetically and spatially defined neuronal populations with excellent temporal control. However, neurons are coupled with other neurons over multiple length scales, and the effects of localized manipulations thus
Externí odkaz:
https://doaj.org/article/a8116898927a47e18b00713a1a1c1009
Publikováno v:
eLife, Vol 8 (2019)
Axon guidance requires interactions between extracellular signaling molecules and transmembrane receptors, but how appropriate context-dependent decisions are coordinated outside the cell remains unclear. Here we show that the transmembrane glycoprot
Externí odkaz:
https://doaj.org/article/52f63657a94944cf9ba28737165c2ce4
Autor:
Hod Dana, Ondrej Novak, Michael Guardado-Montesino, James W Fransen, Amy Hu, Bart G Borghuis, Caiying Guo, Douglas S Kim, Karel Svoboda
Publikováno v:
PLoS ONE, Vol 13, Iss 10, p e0205444 (2018)
Calcium imaging is commonly used to measure the neural activity of large groups of neurons in mice. Genetically encoded calcium indicators (GECIs) can be delivered for this purpose using non-invasive genetic methods. Compared to viral gene transfer,
Externí odkaz:
https://doaj.org/article/8b88862f4edf4231bf55e26405b11718
Publikováno v:
Cell Reports, Vol 2, Iss 1, Pp 76-88 (2012)
Olfactory stimuli are detected by over 1,000 odorant receptors in mice, with each receptor being mapped to specific glomeruli in the olfactory bulb. The trace amine-associated receptors (TAARs) are a small family of evolutionarily conserved olfactory
Externí odkaz:
https://doaj.org/article/7592ad31164d43bc95f5d11f8963869e
Autor:
Hod Dana, Tsai-Wen Chen, Amy Hu, Brenda C Shields, Caiying Guo, Loren L Looger, Douglas S Kim, Karel Svoboda
Publikováno v:
PLoS ONE, Vol 9, Iss 9, p e108697 (2014)
Genetically-encoded calcium indicators (GECIs) facilitate imaging activity of genetically defined neuronal populations in vivo. The high intracellular GECI concentrations required for in vivo imaging are usually achieved by viral gene transfer using
Externí odkaz:
https://doaj.org/article/84ee2ea372c043e3875da1b639043a5b
Autor:
Cheng-Chiu Huang, Ken Sugino, Yasuyuki Shima, Caiying Guo, Suxia Bai, Brett D Mensh, Sacha B Nelson, Adam W Hantman
Publikováno v:
eLife, Vol 2 (2013)
Cerebellar granule cells constitute the majority of neurons in the brain and are the primary conveyors of sensory and motor-related mossy fiber information to Purkinje cells. The functional capability of the cerebellum hinges on whether individual gr
Externí odkaz:
https://doaj.org/article/3b501a9cedd84262b2b68985d93b1435
Autor:
Elisa Barbarese, Marius F Ifrim, Lawrence Hsieh, Caiying Guo, Vedakumar Tatavarty, Michael J Maggipinto, George Korza, Jessica W Tutolo, Anthony Giampetruzzi, Hien Le, Xin-Ming Ma, Eric Levine, Brian Bishop, Duck O Kim, Shigeyuki Kuwada, John H Carson
Publikováno v:
PLoS ONE, Vol 8, Iss 8, p e69989 (2013)
In neurons, specific RNAs are assembled into granules, which are translated in dendrites, however the functional consequences of granule assembly are not known. Tumor overexpressed gene (TOG) is a granule-associated protein containing multiple bindin
Externí odkaz:
https://doaj.org/article/2a62782820864d7987a323e5495becdd
Autor:
Zhen Chen, Momoko Shiozaki, Kelsey M. Haas, Shumei Zhao, Caiying Guo, Benjamin J. Polacco, Zhiheng Yu, Nevan J. Krogan, Robyn M. Kaake, Ronald D. Vale, David A. Agard
Understanding molecular mechanisms of cellular pathways requires knowledge of the identities of participating proteins, their cellular localization and their 3D structures. Contemporary workflows typically require multiple techniques to identify targ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::82a5617082321f0ac705b50fdead3225
https://doi.org/10.1101/2022.09.28.510016
https://doi.org/10.1101/2022.09.28.510016
Autor:
Zhen Chen, Garrett A. Greenan, Momoko Shiozaki, Yanxin Liu, Will M. Skinner, Xiaowei Zhao, Shumei Zhao, Rui Yan, Caiying Guo, Zhiheng Yu, Polina V. Lishko, David A. Agard, Ronald D. Vale
The flagella of mammalian sperm display non-planar, asymmetric beating, in contrast to the planar, symmetric beating of flagella from sea urchin sperm and unicellular organisms. The molecular basis of this difference is unclear. Here, we perform in s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1440bb572e4e401c1bf35a109279b7c0
https://doi.org/10.1101/2022.05.15.492011
https://doi.org/10.1101/2022.05.15.492011