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Akademický článek

Baicalin improves the energy levels in the prefrontal cortex of mice exposed to chronic unpredictable mild stress

Autor: Shuaifei Lu, Caiyin Li, Xiaohui Jin, Leilei Zhu, Jiduo Shen, Ming Bai, Yucheng Li, Erping Xu

Publikováno v: Heliyon, Vol 8, Iss 12, Pp e12083- (2022)

Depression is gradually becoming a primary mental disease threatening human health. Therefore, there is an urgent need to clarify the pathogenesis of depression and identify new effective natural antidepressants. This study aimed to investigate the a

Externí odkaz: https://doaj.org/article/e29c3e019d054ab4a24657e313d35689

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Study on the hepatotoxicity and potential mechanism of gefitinib based on CYP450 in mice and AML12 cells

Autor: Xiaoting Yin, Suzhen Ma, Mengyuan Li, Shuaifei Lu, Changjing Zhang, Hui Liu, Caiyin Li, Pan Su, Ming Bai, Yucheng Li

Publikováno v: Journal of Pharmacy and Pharmacology. 75:407-414

Objectives Gefitinib is mainly used for the treatment of non-small-cell lung cancer. Hepatotoxicity is one of the main side effects of gefitinib, and seriously affects the treatment process of the disease. However, the hepatotoxicity mechanism of gef

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::d6f8d1ce3733cafa91fe311175acd2c7
https://doi.org/10.1093/jpp/rgac091

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Baicalin ameliorates CUMS-induced depression-like behaviors through activating AMPK/PGC-1α pathway and enhancing NIX-mediated mitophagy in mice

Autor: Xiaohui Jin, Leilei Zhu, Shuaifei Lu, Caiyin Li, Ming Bai, Erping Xu, Jiduo Shen, Yucheng Li

Publikováno v: European journal of pharmacology. 938

Mitochondrial dysfunction has been reported to be involved in the pathogenesis of depression, and mitophagy is a key pathway for mitochondrial quality control. This study aimed to investigate the effect of baicalin on mitophagy in the hippocampus of

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::34b1c682cf9b2c5cd6431dd8b4929a35
https://pubmed.ncbi.nlm.nih.gov/36463946

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Electrospark deposition interlayers for dissimilar resistance welding of steel to aluminum

Autor: Norman Y. Zhou, Stephen Peterkin, Caiyin Li, C. DiGiovanni, Pablo D. Enrique

Publikováno v: Manufacturing Letters. 24:123-126

The transportation industry is facing increasing pressure to lightweight vehicles and improve fuel economy. One option is the use of low-density aluminum alloys rather than steels. However, adoption of aluminum alloys is hampered by challenges during

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::3bf092e74a79bed08e794114898702ab
https://doi.org/10.1016/j.mfglet.2020.04.009

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