Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Caiyi Fei"'
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
In the past decade, the substantial achievements of therapeutic cancer vaccines have shed a new light on cancer immunotherapy. The major challenge for designing potent therapeutic cancer vaccines is to identify neoantigens capable of inducing suffici
Externí odkaz:
https://doaj.org/article/9e3bc5a6bd3a4fd799f32518c2186214
SummaryGenetic modifications that cause pivotal protein inactivation or abnormal activation may lead to cell signaling pathway change or even dysfunction, resulting in cancer and other diseases. In turn, dysfunction will further produce “novel prot
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::94b93d501d4fb3301cd7f68e4b4591dc
https://doi.org/10.1101/2023.03.06.531407
https://doi.org/10.1101/2023.03.06.531407
Publikováno v:
SSRN Electronic Journal.
Autor:
Ruikai Du, Jing Liu, Wen Wan, Siyi Hu, Xiaolian Gao, Xiaochuan Zhou, Jiong Hong, Haiyan Liu, Man Xu, Bo Ding, Caiyi Fei, Dongmei Hu
Publikováno v:
Journal of Biotechnology. 194:27-36
We report a rational strategy to design and construct multiple small perturbation mutagenesis (SPM) libraries using massively parallel synthesis of oligonucleotides on a microchip for affinity maturation of an engineered anti-ErbB2 antibody chA21. On