Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Caixue Wang"'
Autor:
Xiaoxue Zhang, Jichen Shao, Caixue Wang, Chao Liu, Han Hao, Xinmeng Li, Yating An, Jinsha He, Weixin Zhao, Yiwen Zhao, Youzhen Kong, Zhanfeng Jia, Shaopo Wan, Yi Yuan, Huiran Zhang, Hailin Zhang, Xiaona Du
Publikováno v:
Cell Reports, Vol 43, Iss 4, Pp 114014- (2024)
Summary: The transmembrane channel-like (TMC) protein family comprises eight members, with TMC1 and TMC2 being extensively studied. This study demonstrates substantial co-expression of TMC7 with the mechanosensitive channel Piezo2 in somatosensory ne
Externí odkaz:
https://doaj.org/article/b52465c7f7294c2c9e9772f03b065690
Autor:
Yating An, Jingyi Hu, Han Hao, Weixin Zhao, Xiaoxue Zhang, Jicheng Shao, Caixue Wang, Xinmeng Li, Chao Liu, Jinsha He, Yiwen Zhao, Hailin Zhang, Xiaona Du
Publikováno v:
Frontiers in Pharmacology, Vol 15 (2024)
Introduction: The transmembrane channel-like (TMC) protein family contains eight members, TMC1–TMC8. Among these members, only TMC1 and TMC2 have been intensively studied. They are expressed in cochlear hair cells and are crucial for auditory sensa
Externí odkaz:
https://doaj.org/article/4b46dc61205b4c78b8f3d0461fa1c5a6
Autor:
Han Hao, Rosmaliza Ramli, Caixue Wang, Chao Liu, Shihab Shah, Pierce Mullen, Varinder Lall, Frederick Jones, Jicheng Shao, Hailin Zhang, David B Jaffe, Nikita Gamper, Xiaona Du
Publikováno v:
PLoS Biology, Vol 21, Iss 1, p e3001958 (2023)
Accumulating observations suggest that peripheral somatosensory ganglia may regulate nociceptive transmission, yet direct evidence is sparse. Here, in experiments on rats and mice, we show that the peripheral afferent nociceptive information undergoe
Externí odkaz:
https://doaj.org/article/c537901d0434420a87a4bcff108dbe55
Autor:
Caixue Wang, Han Hao, Kaitong He, Yating An, Zeyao Pu, Nikita Gamper, Hailin Zhang, Xiaona Du
Publikováno v:
Frontiers in Pharmacology, Vol 12 (2021)
GABA is a major inhibitory neurotransmitter in the mammalian central nervous system (CNS). Inhibitory GABAA channel circuits in the dorsal spinal cord are the gatekeepers of the nociceptive input from the periphery to the CNS. Weakening of these spin
Externí odkaz:
https://doaj.org/article/6616cc7a84fa467f8ebe0c9ac012381f
Autor:
Han Hao, Rosmaliza Ramli, Caixue Wang, Chao Liu, Shihab Shah, Pierce Mullen, Varinder Lall, Frederick Jones, Jicheng Shao, Hailin Zhang, David B. Jaffe, Nikita Gamper, Xiaona Du
Publikováno v:
PLoS biology. 21(1)
Accumulating observations suggest that peripheral somatosensory ganglia may regulate nociceptive transmission, yet direct evidence is sparse. Here, in experiments on rats and mice, we show that the peripheral afferent nociceptive information undergoe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ece162d47c8dbeb4e6d7f1d3acd4acad
https://pubmed.ncbi.nlm.nih.gov/36603052
https://pubmed.ncbi.nlm.nih.gov/36603052
Autor:
Nikita Gamper, Xiaona Du, Hailin Zhang, Han Hao, Caixue Wang, Sylvain Gigout, Yuehui Yang, Dongyang Huang, Li Li, David B. Jaffe, Danielle Sundt
Publikováno v:
Pain
Summary We identified major ion channels influencing the resting membrane potential of nociceptive sensory neurons and demonstrated that changes of somatic/perisomatic membrane potential of these neurons can strongly influence peripheral nociceptive
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d46130443bdf544a85c4bebf90526e7e
http://europepmc.org/articles/PMC4247381
http://europepmc.org/articles/PMC4247381
Autor:
Chris Peers, Jason L. Scragg, Haixia Gao, Hailin Zhang, Nikita Gamper, Pingping Chen, Caixue Wang, Sha Huang, Jinlong Qi, Dongyang Huang, Yani Liu, Xiaona Du, Alexander Vakurov
Publikováno v:
Antioxidants & Redox Signaling
Aims: Neuropeptide substance P (SP) is produced and released by a subset of peripheral sensory neurons that respond to tissue damage (nociceptors). SP exerts excitatory effects in the central nervous system, but peripheral SP actions are still poorly
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cf2e259762455b89a0f5562e045d5649
https://pubmed.ncbi.nlm.nih.gov/27306612
https://pubmed.ncbi.nlm.nih.gov/27306612
Autor:
Li Li, Caixue Wang, Nikita Gamper, Sylvain Gigout, Hailin Zhang, Xiaona Du, Han Hao, Yuehui Yang, Dongyang Huang, Jinlong Qi
Publikováno v:
Biophysical Journal. 106:763a-764a
Purpose: Dorsal root ganglia (DRG) contain somata of peripheral nerve fibres. Somatic excitation is one of the main sources of ectopic firing, which underlies many types of chronic pain. Control of resting membrane potential (Em) of a neuron is a key
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::60ef2fc7a730cbd854f2a1aec88eb47c
https://doi.org/10.1016/j.bpj.2013.11.4199
https://doi.org/10.1016/j.bpj.2013.11.4199
Autor:
Xiaona Du1, Han Hao1, Yuehui Yang1, Sha Huang1, Caixue Wang1, Gigout, Sylvain2, Ramli, Rosmaliza2,3, Xinmeng Li1, Jaworska, Ewa2, Edwards, Ian2, Deuchars, Jim2, Yuchio Yanagawa4, Jinlong Qi1, Bingcai Guan1, Jaffe, David B.5, Hailin Zhang1, Gamper, Nikita1,2, Du, Xiaona (AUTHOR), Hao, Han (AUTHOR), Yang, Yuehui (AUTHOR)
Publikováno v:
Journal of Clinical Investigation. May2017, Vol. 127 Issue 5, p1741-1756. 16p. 3 Diagrams, 6 Graphs.