Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Caixia Suo"'
Autor:
Rui Chen, Zhiyuan Lin, Shengqi Shen, Chuxu Zhu, Kai Yan, Caixia Suo, Rui Liu, Haoran Wei, Li Gao, Kaixiang Fan, Huafeng Zhang, Linchong Sun, Ping Gao
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-15 (2024)
Abstract Citrullination plays an essential role in various physiological or pathological processes, however, whether citrullination is involved in regulating tumour progression and the potential therapeutic significance have not been well explored. H
Externí odkaz:
https://doaj.org/article/ac9e0f6663ed400eb3bfc5fc056796b9
Autor:
Xuemei Gu, Haoran Wei, Caixia Suo, Shengqi Shen, Chuxu Zhu, Liang Chen, Kai Yan, Zhikun Li, Zhenhua Bian, Pinggen Zhang, Mengqiu Yuan, Yingxuan Yu, Jinzhi Du, Huafeng Zhang, Linchong Sun, Ping Gao
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-15 (2023)
Abstract Itaconate is a well-known immunomodulatory metabolite; however, its role in hepatocellular carcinoma (HCC) remains unclear. Here, we find that macrophage-derived itaconate promotes HCC by epigenetic induction of Eomesodermin (EOMES)-mediated
Externí odkaz:
https://doaj.org/article/4163011c71344526b7413ca7b235ea75
Autor:
Yinghui Wang, Hui Lu, Linchong Sun, Xin Chen, Haoran Wei, Caixia Suo, Junru Feng, Mengqiu Yuan, Shengqi Shen, Weidong Jia, Ying Wang, Huafeng Zhang, Zijun Li, Xiuying Zhong, Ping Gao
Publikováno v:
Cell Death and Disease, Vol 12, Iss 10, Pp 1-13 (2021)
Abstract Metformin, the first-line drug for type II diabetes, has recently been considered an anticancer agent. However, the molecular target and underlying mechanism of metformin’s anti-cancer effects remain largely unclear. Herein, we report that
Externí odkaz:
https://doaj.org/article/29cf7987af48434eb91907903f7993ca
Autor:
Shiwei Liang, Chuxu Zhu, Caixia Suo, Haoran Wei, Yingxuan Yu, Xuemei Gu, Liang Chen, Mengqiu Yuan, Shengqi Shen, Shiting Li, Linchong Sun, Ping Gao
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
Staphylococcal nuclease domain-containing protein 1 (SND1) is an evolutionarily conserved multifunctional protein that functions mainly in the nucleus and cytoplasm. However, whether SND1 regulates cellular activity through mitochondrial-related func
Externí odkaz:
https://doaj.org/article/b1974f6d0b114e53a764c360acd65efc
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-13 (2017)
Abstract Perfluorooctane sulfonate (PFOS) is an environmental contaminant that has been manufactured to be used as surfactants and repellents in industry. Due to long half-life for clearance and degradation, PFOS is accumulative in human body and has
Externí odkaz:
https://doaj.org/article/9a0b6495da0c4a4a8105a707fda58a78
Autor:
Jiadong Cheng, Lan Hu, Zheng Yang, Caixia Suo, Yueyang Jack Wang, Ping Gao, Chengbin Cui, Linchong Sun
Publikováno v:
Cells, Vol 8, Iss 5, p 439 (2019)
HIF-1 serves as an important regulator in cell response to hypoxia. Due to its key role in promoting tumor survival and progression under hypoxia, HIF-1 has become a promising target of cancer therapy. Thus far, several HIF-1 inhibitors have been ide
Externí odkaz:
https://doaj.org/article/1687fff9b2484b59aac140a9d67a31a2
Autor:
Huafeng Zhang, Ping Gao, Gregg L. Semenza, Wei-Dong Jia, Yijie Hao, Caixia Suo, Shi-Ting Li, Wenhao Ma, Gongwei Wu, Nana Wang, Tong Zhang, Shengqi Shen, Yongping Cai, Linchong Sun, Zhaoji Liu
Metastasis is responsible for the majority of breast cancer–related deaths, however, the mechanisms underlying metastasis in this disease remain largely elusive. Here we report that under hypoxic conditions, alternative splicing of MBD2 is suppress
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::96a2e49f1bcdcf8cbba97a51d2a1fc33
https://doi.org/10.1158/0008-5472.c.6512746.v1
https://doi.org/10.1158/0008-5472.c.6512746.v1
Autor:
Huafeng Zhang, Ping Gao, Gregg L. Semenza, Wei-Dong Jia, Yijie Hao, Caixia Suo, Shi-Ting Li, Wenhao Ma, Gongwei Wu, Nana Wang, Tong Zhang, Shengqi Shen, Yongping Cai, Linchong Sun, Zhaoji Liu
Supplementary Figures: Figure S1. MBD2a and MBD2c exert opposing roles in BrCa cell migration. Figure S2. Hypoxia inhibits SRSF2-mediated MBD2 splicing. Figure S3. MBD2a and MBD2c inversely regulate EMT markers. Figure S4. DNA methylation controls MB
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::79bd198e5eb10bf5b4ee7a3923319f9d
https://doi.org/10.1158/0008-5472.22427584
https://doi.org/10.1158/0008-5472.22427584
Autor:
Tong Zhang, Linchong Sun, Yijie Hao, Caixia Suo, Shengqi Shen, Haoran Wei, Wenhao Ma, Pinggen Zhang, Ting Wang, Xuemei Gu, Shi-Ting Li, Zhaolin Chen, Ronghui Yan, Yi Zhang, Yongping Cai, Rongbin Zhou, Weidong Jia, Fang Huang, Ping Gao, Huafeng Zhang
Publikováno v:
Nature Cancer. 3:75-89
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::774224020ed2997a99473e617817f82e
https://doi.org/10.1038/s43018-021-00299-1
https://doi.org/10.1038/s43018-021-00299-1
Publikováno v:
Cell Mol Immunol
OX40L is one of the co-stimulatory molecules that can be expressed by splenic lymphoid tissue inducer (Lti) cells, a subset of group 3 innate lymphoid cells (ILC3s). OX40L expression in subsets of intestinal ILC3s and the molecular regulation of OX40
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::17f2f63f2d3557ea6ff368674bb42484
https://doi.org/10.1038/s41423-019-0200-x
https://doi.org/10.1038/s41423-019-0200-x