Zobrazeno 1 - 10
of 31
pro vyhledávání: '"Caiwei, Guo"'
Autor:
Timothy Wu, Jennifer M Deger, Hui Ye, Caiwei Guo, Justin Dhindsa, Brandon T Pekarek, Rami Al-Ouran, Zhandong Liu, Ismael Al-Ramahi, Juan Botas, Joshua M Shulman
Publikováno v:
eLife, Vol 12 (2023)
Aging is a major risk factor for Alzheimer’s disease (AD), and cell-type vulnerability underlies its characteristic clinical manifestations. We have performed longitudinal, single-cell RNA-sequencing in Drosophila with pan-neuronal expression of hu
Externí odkaz:
https://doaj.org/article/38917c6a7164451fa76d94b52a50b80c
Autor:
Carl Grant Mangleburg, Timothy Wu, Hari K. Yalamanchili, Caiwei Guo, Yi-Chen Hsieh, Duc M. Duong, Eric B. Dammer, Philip L. De Jager, Nicholas T. Seyfried, Zhandong Liu, Joshua M. Shulman
Publikováno v:
Molecular Neurodegeneration, Vol 15, Iss 1, Pp 1-17 (2020)
Abstract Background Tau neurofibrillary tangle pathology characterizes Alzheimer’s disease and other neurodegenerative tauopathies. Brain gene expression profiles can reveal mechanisms; however, few studies have systematically examined both the tra
Externí odkaz:
https://doaj.org/article/110a287c3f324a6eb0a20036440b10b1
Autor:
Caiwei Guo, Aaron D. Gitler
Publikováno v:
Molecular Cell. 82:4194-4196
In this issue of Molecular Cell, Gropp et al. identify how the cellular background affects whether or not the Huntington's disease protein will form toxic pathological aggregates, providing insight into selective neuronal vulnerability in neurodegene
Autor:
Yi-Chen Hsieh, Caiwei Guo, Hari K. Yalamanchili, Measho Abreha, Rami Al-Ouran, Yarong Li, Eric B. Dammer, James J. Lah, Allan I. Levey, David A. Bennett, Philip L. De Jager, Nicholas T. Seyfried, Zhandong Liu, Joshua M. Shulman
Publikováno v:
Cell Reports, Vol 29, Iss 2, Pp 301-316.e10 (2019)
Summary: In Alzheimer’s disease (AD), spliceosomal proteins with critical roles in RNA processing aberrantly aggregate and mislocalize to Tau neurofibrillary tangles. We test the hypothesis that Tau-spliceosome interactions disrupt pre-mRNA splicin
Externí odkaz:
https://doaj.org/article/f861f0027d6049188b93ab234a7736d1
Autor:
X. Rosa Ma, Mercedes Prudencio, Yuka Koike, Sarat C. Vatsavayai, Garam Kim, Fred Harbinski, Adam Briner, Caitlin M. Rodriguez, Caiwei Guo, Tetsuya Akiyama, H. Broder Schmidt, Beryl B. Cummings, David W. Wyatt, Katherine Kurylo, Georgiana Miller, Shila Mekhoubad, Nathan Sallee, Gemechu Mekonnen, Laura Ganser, Jack D. Rubien, Karen Jansen-West, Casey N. Cook, Sarah Pickles, Björn Oskarsson, Neill R. Graff-Radford, Bradley F. Boeve, David S. Knopman, Ronald C. Petersen, Dennis W. Dickson, James Shorter, Sua Myong, Eric M. Green, William W. Seeley, Leonard Petrucelli, Aaron D. Gitler
Publikováno v:
Nature. 603:124-130
A hallmark pathological feature of the neurodegenerative diseases amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD) is the depletion of RNA-binding protein TDP-43 from the nucleus of neurons in the brain and spinal cord1. A major
Autor:
Caiwei Guo, Yuxiang Cai, Wen Ji, Qimin Xiao, Shulin Wu, Weitao Zheng, Wei Zhou, Taining Huang, Jianxiong Huang
Publikováno v:
2022 IEEE Conference on Telecommunications, Optics and Computer Science (TOCS).
Autor:
Timothy Wu, Caiwei Guo, Jennifer Marie Deger, Justin Dhindsa, Rami Al‐Ouran, Joshua M Shulman
Publikováno v:
Alzheimer's & Dementia. 18
Autor:
Timothy Wu, Jennifer M Deger, Hui Ye, Caiwei Guo, Justin Dhindsa, Brandon T Pekarek, Rami Al-Ouran, Zhandong Liu, Ismael Al-Ramahi, Juan Botas, Joshua M Shulman
SummaryAging is a major risk factor for Alzheimer’s disease (AD), and cell-type vulnerability underlies its characteristic clinical manifestations. We have performed longitudinal, single-cell RNA-sequencing inDrosophilawith pan-neuronal expression
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2beee62f970544c70d28560784800188
https://doi.org/10.1101/2022.11.14.516410
https://doi.org/10.1101/2022.11.14.516410
Autor:
Wu, Timothy, Deger, Jennifer M., Hui Ye, Caiwei Guo, Dhindsa, Justin, Pekarek, Brandon T., Al-Ouran, Rami, Zhandong Liu, Al-Ramahi, Ismael, Botas, Juan, Shulman, Joshua M.
Publikováno v:
eLife; 6/9/2023, p1-31, 31p
Autor:
X Rosa, Ma, Mercedes, Prudencio, Yuka, Koike, Sarat C, Vatsavayai, Garam, Kim, Fred, Harbinski, Adam, Briner, Caitlin M, Rodriguez, Caiwei, Guo, Tetsuya, Akiyama, H Broder, Schmidt, Beryl B, Cummings, David W, Wyatt, Katherine, Kurylo, Georgiana, Miller, Shila, Mekhoubad, Nathan, Sallee, Gemechu, Mekonnen, Laura, Ganser, Jack D, Rubien, Karen, Jansen-West, Casey N, Cook, Sarah, Pickles, Björn, Oskarsson, Neill R, Graff-Radford, Bradley F, Boeve, David S, Knopman, Ronald C, Petersen, Dennis W, Dickson, James, Shorter, Sua, Myong, Eric M, Green, William W, Seeley, Leonard, Petrucelli, Aaron D, Gitler
Publikováno v:
Nature, vol 603, iss 7899
A hallmark pathological feature of the neurodegenerative diseases amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD) is the depletion of RNA-binding protein TDP-43 from the nucleus of neurons in the brain and spinal cord1. A major
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::821110b3bc35110fc73e4b0933142d1d
https://escholarship.org/uc/item/1062r1nd
https://escholarship.org/uc/item/1062r1nd