Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Caitriona Dennis"'
Autor:
Caitriona Dennis, Nancy Davies
Publikováno v:
Medical Teacher. 43:1255-1260
When students attend clinical attachments in diverse locations, a key challenge is in ensuring consistently good teaching over all areas. To meet this challenge, a faculty development intervention called TiMEtoTeach was created with the aim of reachi
Autor:
Simon E. V. Phillips, S.W. Lane, Caitriona Dennis, Peter G. Stockley, C.L. Lane, Pierre J. Rizkallah, Chi H. Trinh
Publikováno v:
Journal of Molecular Biology. 413:41-50
A codon-optimised gene has been expressed in Escherichia coli to produce the coat protein (CP) of the Satellite Tobacco Necrosis Virus. This protein assembles in vivo into capsids closely resembling those of the T = 1 wild-type virus. These virus-lik
Autor:
Chi H. Trinh, Alan Berry, Arwen R. Pearson, Adam Nelson, Thomas Harman, Amanda H. Bolt, Ivan Campeotto, Simon E. V. Phillips, Caitriona Dennis
Publikováno v:
Journal of Molecular Biology
The substrate specificity of Escherichia coli N-acetylneuraminic acid lyase was previously switched from the natural condensation of pyruvate with N-acetylmannosamine, yielding N-acetylneuraminic acid, to the aldol condensation generating N-alkylcarb
Autor:
Caitriona Dennis, Mark Harris, Andrew J. Baron, Joachim Jaeger, Sabine Mazaleyrat, J. Günter Grossmann
Publikováno v:
Proteins: Structure, Function, and Bioinformatics. 60:658-669
We have studied the solution properties of Nef, a 24-kDa cotranslationally myristoylated protein produced by HIV-1 and other primate lentiviruses. Nef is found in the cytosol and also in association with cytoplasmic membranes, the latter, mediated in
Publikováno v:
Acta Crystallographica Section D Biological Crystallography. 58:421-430
In the Gram-positive bacterium Bacillus subtilis the concentration of the amino acid L-arginine is controlled by the transcriptional regulator AhrC. The hexameric AhrC protein binds in an L-arginine-dependent manner to pseudo-palindromic operators wi
Publikováno v:
Cell and Tissue Research
The cell surface hydrolase tissue non-specific alkaline phosphatase (TNAP) (also known as MSCA-1) is used to identify a sub-population of bone marrow stromal cells (BMSCs) with high mineralising potential and is found on subsets of cells within the d
Autor:
Dean J. Derbyshire, Siân Rowsell, Garib N. Murshudov, Richard A. Pauptit, Alexander L. Breeze, Caitriona Dennis, Simon A. Weston
Publikováno v:
Acta Crystallographica Section D Biological Crystallography. 57:1397-1404
Two cases of successful molecular replacement using NMR trial models are presented. One is the crystal structure of the Escherichia coli colicin immunity protein Im7; the other is a heretofore unreported crystal structure of a specific PDGF receptor-
Autor:
Timothy R. Dafforn, Airlie J. McCoy, Irmgard Sinning, Philip A.S Lowden, Tanja Kortemme, M.A. Convery, Ora Schueler-Furman, Jon D. Stewart, Richard Newman, Gianfranco Gilardi, Andreas K. Engel, Alex Watters, Caitriona Dennis, Richard R. Copley, Siân Rowsell, Sabine L. Flitsch, Martin E.M. Noble, Gary N. Parkinson, Andras Fiser
Publikováno v:
Current Opinion in Structural Biology. 11:501-510
Autor:
Andreas K. Engel, Philip A.S Lowden, Richard R. Copley, Richard Newman, Martin E.M. Noble, Gianfranco Gilardi, Siân Rowsell, M.A. Convery, Andras Fiser, Gary N. Parkinson, Alex Watters, Irmgard Sinning, Sehat Nauli, Sabine L. Flitsch, Tanja Kortemme, Jon D. Stewart, Caitriona Dennis, Steve Matthews
Publikováno v:
Current Opinion in Structural Biology. 11:263-270
Publikováno v:
Chembiochem
The early work of Edsall[1] illustrated the effect of nonpolar groups in raising the apparent heat capacities of solutes in aqueous solution. Subsequently, the hydrophobic effect has been well established as the result of the formation of structured