Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Caitlyn Meinzer"'
Autor:
Guangyi Gao, Byron J. Gajewski, Jo Wick, Jonathan Beall, Jeffrey L. Saver, Caitlyn Meinzer, the STEP-STONE Executive Committee
Publikováno v:
Trials, Vol 23, Iss 1, Pp 1-15 (2022)
Abstract Background Platform trials are well-known for their ability to investigate multiple arms on heterogeneous patient populations and their flexibility to add/drop treatment arms due to efficacy/lack of efficacy. Because of their complexity, it
Externí odkaz:
https://doaj.org/article/f9c6cbad423f4729be43844fc66eb060
Autor:
Na Jin Seo, Derek G. Kamper, Viswanathan Ramakrishnan, Jillian B. Harvey, Christian Finetto, Christian Schranz, Gabrielle Scronce, Kristen Coupland, Keith Howard, Jenna Blaschke, Adam Baker, Caitlyn Meinzer, Craig A. Velozo, Robert J. Adams
Publikováno v:
Trials, Vol 23, Iss 1, Pp 1-14 (2022)
Abstract Background Functional task performance requires proper control of both movement and force generation in three-dimensional space, especially for the hand. Control of force in three dimensions, however, is not explicitly treated in current phy
Externí odkaz:
https://doaj.org/article/018bb0f1f192442bbbc8105138e0c696
Autor:
Na Jin Seo, Viswanathan Ramakrishnan, Michelle L. Woodbury, Leonardo Bonilha, Christian Finetto, Christian Schranz, Gabrielle Scronce, Kristen Coupland, Jenna Blaschke, Adam Baker, Keith Howard, Caitlyn Meinzer, Craig A. Velozo, Robert J. Adams
Publikováno v:
Trials, Vol 23, Iss 1, Pp 1-15 (2022)
Abstract Background Post-stroke hand impairment is prevalent and persistent even after a full course of rehabilitation. Hand diminishes stroke survivors’ abilities for activities of daily living and independence. One way to improve treatment effica
Externí odkaz:
https://doaj.org/article/dfead78af418413ebd40e5ae9b374c53
Publikováno v:
BMC Medical Research Methodology, Vol 20, Iss 1, Pp 1-17 (2020)
Abstract Background Monitoring and reporting of drug safety during a clinical trial is essential to its success. More recent attention to drug safety has encouraged statistical methods development for monitoring and detecting potential safety signals
Externí odkaz:
https://doaj.org/article/f60ac27b22924783a7c658d7cacb2d4f
Bayesian dose selection design for a binary outcome using restricted response adaptive randomization
Publikováno v:
Trials, Vol 18, Iss 1, Pp 1-11 (2017)
Abstract Background In phase II trials, the most efficacious dose is usually not known. Moreover, given limited resources, it is difficult to robustly identify a dose while also testing for a signal of efficacy that would support a phase III trial. R
Externí odkaz:
https://doaj.org/article/c94dff75341b472aa18b4fdf1980e6ac
Publikováno v:
BMC Medical Research Methodology, Vol 20, Iss 1, Pp 1-1 (2020)
An amendment to this paper has been published and can be accessed via the original article.
Externí odkaz:
https://doaj.org/article/144c6f86623b43a1af7e4a4b7eea7447
Autor:
Daniel Ganger, Jody C. Olson, R. Todd Stravitz, Iris Liou, Robert J. Fontana, Brendan M. McGuire, Ton Lisman, Jody Rule, Bilal Hamid, Kristin Clasen, Michael W. Cripps, David G. Koch, Constantine J. Karvellas, Valerie Durkalski-Mauldin, Adrian Reuben, William M. Lee, Michael L. Schilsky, Caitlyn Meinzer, A. James Hanje
Publikováno v:
Hepatology, 74(2), 937-949. Wiley
Background and Aims: Patients with acute liver injury or failure (ALI/ALF) experience bleeding complications uncommonly despite an abnormal hemostatic profile. Rotational thromboelastometry (ROTEM), which assesses clot formation in whole blood, was u
Autor:
Rachael Schutz, Richard Kronmal, Susan R Heckbert, Caitlyn Meinzer, David L Tirschwell, Hooman Kamel, Mitchell Elkind, W T Longstreth
Publikováno v:
Stroke. 53
Introduction: Elevated N-terminal pro-brain natriuretic peptide (NT-proBNP) and prolonged P-wave terminal force in V1 (PTFV1) on 12-lead ECG are associated with increased risk of atrial fibrillation and stroke. Age is positively associated with NT-pr
Autor:
Chinwe Ibeh, Caitlyn Meinzer, Mitchell S Elkind, Hooman Kamel, W T Longstreth, David L Tirschwell, Rebeca Aragon Garcia, Pam Plummer, Joe Broderick, Marco Di Tullio
Publikováno v:
Stroke. 53
Background: Recent data suggest biomarkers of atrial cardiopathy (ACP) can potentially identify a subset of patients with cryptogenic stroke who may benefit from anticoagulation. However, the specificity of these markers for atrial disease and their
Publikováno v:
Dig Dis Sci
Psychiatric co-morbidities are thought to deter listing of patients with acetaminophen-induced acute liver failure (APAP-ALF) for liver transplantation (LT). We examined the listing process and short-term outcomes via a cohort study of APAP-ALF patie