Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Caitlyn Mahony"'
Autor:
Erin Buchanan, Caitlyn Mahony, Sophia Bam, Mohamed Jaffer, Sarah Macleod, Asandile Mangali, Mignon van der Watt, Sholto de Wet, Rensu Theart, Caron Jacobs, Ben Loos, Colleen O’Ryan
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-13 (2023)
Abstract Propionic acid (PPA) is used to study the role of mitochondrial dysfunction in neurodevelopmental conditions like autism spectrum disorders. PPA is known to disrupt mitochondrial biogenesis, metabolism, and turnover. However, the effect of P
Externí odkaz:
https://doaj.org/article/ea405245f5cb4ff49942b613f24a7e03
Publikováno v:
IBRO Neuroscience Reports, Vol 15, Iss , Pp S147- (2023)
Externí odkaz:
https://doaj.org/article/93f81b7b3ce94a0e8241dcb29e6f09a4
Autor:
Caitlyn Mahony, Colleen O'Ryan
Publikováno v:
Frontiers in Psychiatry, Vol 13 (2022)
Molecular autism research is evolving toward a biopsychosocial framework that is more informed by autistic experiences. In this context, research aims are moving away from correcting external autistic behaviors and toward alleviating internal distres
Externí odkaz:
https://doaj.org/article/9da373e8bc5e49b9a12feee90a18b516
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 9 (2021)
Autism spectrum disorder (ASD) is a complex disorder that is underpinned by numerous dysregulated biological pathways, including pathways that affect mitochondrial function. Epigenetic mechanisms contribute to this dysregulation and DNA methylation i
Externí odkaz:
https://doaj.org/article/9b8ff11c7dbf4400a076f8549b26f12c
Autor:
Erin Buchanan, Caitlyn Mahony, Sophia Bam, Mohamed Jaffer, Sarah Macleod, Mignon Van Der Watt, Caron Jacobs, Colleen O'Ryan
Mitochondrial dysregulation is implicated in numerous neurological disorders. Mitochondrial dynamics, including biogenesis, fusion and fission, are essential components of mitostasis which is modulated by complex regulatory mechanisms. Although expre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a8f55601231908d0f20409268198348c
The increased awareness of autism spectrum disorders (ASD) is accompanied by burgeoning ASD research, and concerted research efforts are trying to elucidate the molecular ASD aetiology. However, much of this research is concentrated in the Global Nor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d77c71d94ba8808c7be8fc0066de0dc0
https://doi.org/10.1101/2022.11.11.516128
https://doi.org/10.1101/2022.11.11.516128
Publikováno v:
European Neuropsychopharmacology. 63:e246-e247
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::09961ec0dbb60eacc671a7436c7a0b47
https://doi.org/10.1016/j.euroneuro.2022.07.441
https://doi.org/10.1016/j.euroneuro.2022.07.441
Autor:
Caitlyn Mahony, Colleen O'Ryan
Publikováno v:
International Journal of Molecular Sciences
International Journal of Molecular Sciences, Vol 22, Iss 10757, p 10757 (2021)
International Journal of Molecular Sciences, Vol 22, Iss 10757, p 10757 (2021)
Autism Spectrum Disorder (ASD) is a complex neurodevelopmental disorder with extensive genetic and aetiological heterogeneity. While the underlying molecular mechanisms involved remain unclear, significant progress has been facilitated by recent adva
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::64b919d722f314bc2aaf70e4105bf475
https://pubmed.ncbi.nlm.nih.gov/34639097
https://pubmed.ncbi.nlm.nih.gov/34639097
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 9 (2021)
Frontiers in Cell and Developmental Biology
Frontiers in Cell and Developmental Biology
Autism spectrum disorder (ASD) is a complex disorder that is underpinned by numerous dysregulated biological pathways, including pathways that affect mitochondrial function. Epigenetic mechanisms contribute to this dysregulation and DNA methylation i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::29fc2aca0cae98282b0eb35ac13c7dcf
https://www.frontiersin.org/articles/10.3389/fcell.2021.696428/full
https://www.frontiersin.org/articles/10.3389/fcell.2021.696428/full
Autor:
Zander Lindeque, Renaud Gaujoux, Caitlyn Mahony, Rachelle Van Der Colff, Sofia Stathopoulos, Colleen O'Ryan, Francois H. van der Westhuizen
Publikováno v:
Autism Research
Autism spectrum disorder (ASD) is characterized by phenotypic heterogeneity and a complex genetic architecture which includes distinctive epigenetic patterns. We report differential DNA methylation patterns associated with ASD in South African childr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::265ff72ab14896b2930ecbdaae83c251
https://hdl.handle.net/10394/34755
https://hdl.handle.net/10394/34755