Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Caitlyn L McCafferty"'
Autor:
Caitlyn L McCafferty, Ophelia Papoulas, Mareike A Jordan, Gabriel Hoogerbrugge, Candice Nichols, Gaia Pigino, David W Taylor, John B Wallingford, Edward M Marcotte
Publikováno v:
eLife, Vol 11 (2022)
Intraflagellar transport (IFT) is a conserved process of cargo transport in cilia that is essential for development and homeostasis in organisms ranging from algae to vertebrates. In humans, variants in genes encoding subunits of the cargo-adapting I
Externí odkaz:
https://doaj.org/article/5936f1f2344a45909019f9e1c8895338
Autor:
Caitlyn L McCafferty, Yuri V Sergeev
Publikováno v:
PLoS ONE, Vol 13, Iss 1, p e0191881 (2018)
[This corrects the article DOI: 10.1371/journal.pone.0189064.].
Externí odkaz:
https://doaj.org/article/1108402056cb4c3698468cfc1c82cb4f
Autor:
Caitlyn L McCafferty, Yuri V Sergeev
Publikováno v:
PLoS ONE, Vol 12, Iss 12, p e0189064 (2017)
A protein's amino acid sequence dictates the folds and final structure the macromolecule will form. We propose that by identifying critical residues in a protein's atomic structure, we can select a critical stability framework within the protein stru
Externí odkaz:
https://doaj.org/article/5e75e42dad08453185db6d4209d6dad4
Autor:
Evan A. Schwartz, Jack P. K. Bravo, Mohd Ahsan, Luis A. Macias, Caitlyn L. McCafferty, Tyler L. Dangerfield, Jada N. Walker, Jennifer S. Brodbelt, Giulia Palermo, Peter C. Fineran, Robert D. Fagerlund, David W. Taylor
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-14 (2024)
Abstract CRISPR-Cas are adaptive immune systems in bacteria and archaea that utilize CRISPR RNA-guided surveillance complexes to target complementary RNA or DNA for destruction1–5. Target RNA cleavage at regular intervals is characteristic of type
Externí odkaz:
https://doaj.org/article/df1f8e1485e54ad7bc5ecc11d0bc3d0e
Autor:
Avrin Ghanaeian, Sumita Majhi, Caitlyn L. McCafferty, Babak Nami, Corbin S. Black, Shun Kai Yang, Thibault Legal, Ophelia Papoulas, Martyna Janowska, Melissa Valente-Paterno, Edward M. Marcotte, Dorota Wloga, Khanh Huy Bui
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-15 (2023)
Abstract Cilia are hairlike protrusions that project from the surface of eukaryotic cells and play key roles in cell signaling and motility. Ciliary motility is regulated by the conserved nexin-dynein regulatory complex (N-DRC), which links adjacent
Externí odkaz:
https://doaj.org/article/0caf9d6c54f2470f93614bf623443134
Autor:
Shintaroh Kubo, Corbin S. Black, Ewa Joachimiak, Shun Kai Yang, Thibault Legal, Katya Peri, Ahmad Abdelzaher Zaki Khalifa, Avrin Ghanaeian, Caitlyn L. McCafferty, Melissa Valente-Paterno, Chelsea De Bellis, Phuong M. Huynh, Zhe Fan, Edward M. Marcotte, Dorota Wloga, Khanh Huy Bui
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-16 (2023)
Abstract Cilia are ubiquitous eukaryotic organelles responsible for cellular motility and sensory functions. The ciliary axoneme is a microtubule-based cytoskeleton consisting of two central singlets and nine outer doublet microtubules. Cryo-electron
Externí odkaz:
https://doaj.org/article/3b866ad18ed6419bafadde4fb6563a61
Autor:
Caitlyn L. McCafferty, Erin L. Pennington, Ophelia Papoulas, David W. Taylor, Edward M. Marcotte
Publikováno v:
Communications Biology, Vol 6, Iss 1, Pp 1-10 (2023)
Abstract A major goal in structural biology is to understand protein assemblies in their biologically relevant states. Here, we investigate whether AlphaFold2 structure predictions match native protein conformations. We chemically cross-linked protei
Externí odkaz:
https://doaj.org/article/52df4cef827346098d028bcb11deb9a7
Autor:
Caitlyn L. McCafferty, Ophelia Papoulas, Chanjae Lee, Khanh Huy Bui, David W. Taylor, Edward M. Marcotte, John B. Wallingford
This data includes XL/MS and structural models for the Tetrahymena motile cilia interactome.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::19839541f802db47ca4d245a8863cce9
Autor:
Caitlyn L McCafferty, Ophelia Papoulas, Mareike A Jordan, Gabriel Hoogerbrugge, Candice Nichols, Gaia Pigino, David W Taylor, John B Wallingford, Edward M Marcotte
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8693d9b7662730c84a8748dfd15b4197
https://doi.org/10.7554/elife.81977.sa2
https://doi.org/10.7554/elife.81977.sa2
Autor:
Caitlyn L. McCafferty, Erin L. Pennington, Ophelia Papoulas, David W. Taylor, Edward M. Marcotte
A major goal in structural biology is to understand protein assemblies in their biologically relevant states. Here, we investigate whether AlphaFold2 structure predictions match native protein conformations. We chemically cross-linked proteins in sit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::57b6c000409ff7e0c566d5ecdbd56a6a
https://doi.org/10.1101/2022.08.25.505345
https://doi.org/10.1101/2022.08.25.505345